Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,627 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT05955170RecruitingPhase 2
Tucatinib plus oral chemo and trastuzumab for metastatic HER2+ breast cancer
This Phase 2 trial studies tucatinib combined with oral etoposide and trastuzumab in people with metastatic HER2-positive breast cancer, aiming to slow cancer growth. You may be eligible if you previously had progression on a similar HER2-targeted treatment or cannot take capecitabine for medical reasons.
Clermont-Ferrand, Clermont FerrandAges 18 years+ - NCT07258108RecruitingPhase 2
Sac-TMT and KL-A167 for HR+/HER2- Breast Cancer
This trial is testing a combination of two drugs, Sac-TMT and KL-A167, in people with a certain type of advanced breast cancer (HR+/HER2-) that is PD-L1 positive. It's for those whose cancer has gotten worse after treatment with a CDK4/6 inhibitor and hormone therapy.
Guangzhou, GuangdongAges 18–75 - NCT07252726RecruitingPhase 4
Morning vs. evening dosing for metastatic breast or prostate cancer
This trial tests whether taking your hormone therapy and targeted pills in the morning or evening affects how well they work and how you feel. It is for people with metastatic breast or prostate cancer starting a specific hormone-based treatment combination.
Kitchener, OntarioAges 18 years+ - NCT07257484RecruitingPhase 4
Tirzepatide study for breast cancer survivors with obesity
This trial tests if tirzepatide, a weight-loss medication, can help postmenopausal women with hormone-positive breast cancer who have obesity. It aims to improve health outcomes after completing cancer treatment.
New York, New YorkAges 18 years+ - NCT06811870RecruitingPhase 1/Phase 2
Hyperbaric oxygen before surgery for breast cancer
This trial tests adding hyperbaric oxygen (breathing pure oxygen in a pressurized chamber) before standard chemotherapy for breast cancer. The goal is to see if it helps shrink the tumor more effectively before surgery.
Guangzhou, GuangdongAges 18–60 - NCT07242118Recruiting
Radiation therapy for older women with breast cancer
This trial tests a precise, high-dose radiation treatment (called SABR) for older women with early-stage breast cancer who choose not to have surgery. It aims to control the tumor with fewer side effects and may be an option if you have a small, ER+, HER2- tumor that hasn't spread to lymph nodes.
Kansas City, KansasAges 65 years+ - NCT07242352RecruitingPhase 3
Comparing elacestrant to standard hormone therapy for high-risk early breast cancer
This trial tests a new hormone therapy drug called elacestrant against standard hormone treatments for people with a specific type of early breast cancer (ER+/HER2-) that has a high chance of coming back. The goal is to see if elacestrant works better at keeping the cancer from returning.
Mannheim, Baden-WurttembergAges 18 years+ - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+ - NCT07244094Recruiting
AI predicts breast cancer spread risk from tissue scans
This trial uses artificial intelligence to analyze images of your tumor tissue to predict if breast cancer might spread to other parts of the body. It may help doctors better understand your individual risk and guide treatment decisions.
Changchun, JilinAges 18–95 - NCT06797258Recruiting
FlexHD for Breast Reconstruction After Mastectomy
This study tests a special type of tissue support (FlexHD Pliable) used during breast reconstruction right after a mastectomy. It may help women who want implants placed above the chest muscle.
Fort Worth, TexasAges 22 years+ - NCT07236658Recruiting
Using AI to detect arm problems after breast cancer surgery
This trial uses artificial intelligence (a computer program) to help predict arm and shoulder problems that can happen after breast cancer surgery. It aims to find these issues early so they can be treated better.
AnkaraAges 18 years+ - NCT07235176RecruitingPhase 1/Phase 2
QLS1304 plus hormone therapy for ER+ breast cancer
This trial tests a new drug called QLS1304 combined with hormone therapy for people with ER-positive, HER2-negative breast cancer that has spread or come back and no longer responds to hormone therapy alone. The goal is to see if this combination can help shrink tumors or slow the disease.
ShanghaiAges 18 years+ - NCT07238894Recruiting
Freezing and heating breast cancer without surgery
This study tests a combination of freezing and heating (cryoablation and thermal ablation) to treat breast cancer in patients who cannot have surgery. It may help shrink or control tumors while avoiding general anesthesia.
BeijingAges 18–80 - NCT07237256RecruitingPhase 3
Testing less chemo for HR+ HER2- breast cancer with ribociclib
This trial tests whether some people with hormone receptor-positive, HER2-negative early breast cancer can safely receive less chemotherapy when also taking the targeted drug ribociclib after surgery. You may qualify if you have a specific stage of breast cancer and are planning to take hormone therapy for at least 5 years.
AmiensAges 18 years+ - NCT07233499RecruitingPhase 2
Nebivolol for heart protection during breast cancer treatment
This trial tests if the drug nebivolol can protect the heart from damage caused by trastuzumab (Herceptin) in women with HER2-positive breast cancer. If effective, it may help prevent heart problems while still allowing cancer treatment.
CairoAges 18–65 - NCT07231159Recruiting
Cancer screening help at community spots
This trial tests a program to help people get screened for lung, breast, or prostate cancer at community resource spots. If you are at risk and screen positive, you may be able to join.
Orlando, FloridaAges 18 years+ - NCT07227233RecruitingPhase 2
AI-guided retrial of CDK4/6 inhibitors for advanced breast cancer
This trial tests whether an artificial intelligence (AI) tool can help doctors decide if it is safe and effective to give you a second course of a CDK4/6 inhibitor drug (like palbociclib, ribociclib, or abemaciclib) plus hormone therapy for advanced (unresectable or metastatic) HR+/HER2- breast cancer. The goal is to only treat people whose cancer is likely to respond based on a special AI analysis of their tumor tissue.
La Jolla, CaliforniaAges 18 years+ - NCT07228000Recruiting
Cancer screening and genetic services navigation for Black and Hispanic women
This study helps Black and Hispanic women ages 45-74 get both breast and colorectal cancer screenings and genetic services. It provides a navigator to guide you through the process.
Newark, DelawareAges 45–74 - NCT06911528Recruiting
New cell-probing technology for early breast cancer surgery
This trial tests a new technology that helps doctors examine cells during surgery for early-stage breast cancer. It may help make the sentinel lymph node biopsy more accurate.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06505577Recruiting
Comparing Tumor Size Before and After Breast Cancer Surgery
This study compares the size of a breast tumor measured before surgery (using imaging tests like mammogram or ultrasound) with the actual size found after the tumor is removed. It helps understand how accurate preoperative measurements are for patients having breast cancer surgery.
IncheonAges 19 years+ - NCT05406635Recruiting
Imaging vs blood tests to guide heart-safe HER2 treatment
This trial compares whether special heart imaging or blood tests better helps monitor heart safety while you receive HER2-targeted therapy (like trastuzumab, with or without pertuzumab) plus chemotherapy. It may help doctors catch early heart stress and choose the safest treatment plan for you.
AalborgAges 18–90 - NCT05013255RecruitingPhase 2
Pioglitazone to treat fatigue in hormone-positive breast cancer
This Phase 2 study tests whether pioglitazone can reduce fatigue in people with certain types of breast cancer. You may be eligible if your cancer is estrogen- and progesterone-positive (ER+/PR+) and you plan surgery soon.
Morgantown, West VirginiaAges 18 years+ - NCT07219277Recruiting
Blood test to detect breast cancer early in women
This study tests a new blood test that aims to find breast cancer early in women who are at higher risk or are going for routine screening. If you are a woman aged 30–75 and are scheduled for a mammogram, MRI, or breast ultrasound, you may be able to help validate this test.
Phoenix, ArizonaAges 30–75
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,627 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.