Clinical trials
Calcification clinical trials
Below are recruiting calcification clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT06688448Recruiting
New biologic aortic valve replacement study
This study is testing a new generation of biologic (tissue) replacement valves for the aortic valve in adults aged 18 to 65. It aims to see how well these newer devices work compared to standard options.
São Paulo, São PauloAges 18–65 - NCT07001800RecruitingPhase 2/Phase 3
Slowing aortic valve disease with ataciguat
This trial tests a new pill, ataciguat, to slow down the progression of moderate calcific aortic valve stenosis (a condition where your aortic valve stiffens). If you have moderate valve narrowing and meet the other criteria, participation could help find a way to delay needing surgery.
Birmingham, AlabamaAges 50 years+ - NCT06722066Recruiting
TAVR and heart valve calcium study
This study looks at how calcium buildup in the aortic valve affects long-term results after a TAVR procedure (a minimally invasive heart valve replacement). It may help doctors understand which patients do better over time.
SeoulAges 19 years+ - NCT06736665Recruiting
Comparing two ways to treat hardened calcium in heart arteries
This trial compares two techniques (orbital atherectomy and intravascular lithotripsy) to break up tough calcium deposits in the heart's arteries that can block blood flow. If you have a calcified nodule and are having a non-emergency procedure to open a blocked artery, this study may help guide which method works best.
Alicante, AlicanteAges 18 years+ - NCT06853340Recruiting
Calcium and blood vessel hardening in sepsis shock
This study looks at how calcium buildup in blood vessels and a specific receptor on immune cells might affect recovery from septic shock. It aims to understand if these factors impact how well patients respond to treatment.
AmiensAges 18 years+ - NCT07000045Recruiting
Shock wave vs drill for hard calcium in heart arteries
This study tests a new way to break up hard calcium deposits in heart arteries using shock waves (lithotripsy), with or without a special drill (rotational atherectomy), before placing a stent. It may help people with severely calcified blockages that are hard to treat with standard methods.
New York, New YorkAges 18 years+ - NCT07069673Recruiting
Abbott Cephea mitral valve disease registry
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
Birmingham, AlabamaAges 18 years+ - NCT07201649Recruiting
Liver disease and artery calcification study
This study looks at how liver function and scarring affect calcium buildup in arteries. It may help people waiting for a liver transplant understand these changes.
Nice, Alpes-maritimesAges 18 years+ - NCT01886950Recruiting
Bone and blood-vessel changes around kidney transplant
This study looks at how bone structure and blood-vessel calcification change before and after a kidney transplant. It may help doctors better understand what to monitor for long-term health after transplantation.
Leuven, Vlaams-BrabantAges 18 years+ - NCT02813642Recruiting
Study of heart risk in people starting dialysis
This study looks at heart (cardiovascular) risk factors in people who are just starting dialysis for chronic kidney failure. It may help doctors better understand what heart-related issues to watch for early during dialysis.
Castelnau-le-LezAges 18–90 - NCT02808572Recruiting
Blood and urine tests to study heart risk in kidney disease
This study looks for new markers in blood or urine that may help explain heart (cardiovascular) risk in people with chronic kidney disease. It may help doctors better predict risk, especially in those not yet on dialysis.
MontpellierAges 18–95 - NCT03032835Recruiting
Research study for calciphylaxis skin lesions
This study collects and stores information from people with calciphylaxis, a serious condition that causes painful skin lesions. It may help researchers learn more about the disease and improve future care.
Boston, MassachusettsAges 18 years+ - NCT05851209Recruiting
Study biomarkers in people with moderate aortic valve narrowing
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
BonnAges 18 years+ - NCT07511283Recruiting
Calciphylaxis study in kidney disease patients
This study looks at a rare condition called calciphylaxis (hardening of small blood vessels) that can happen in people with chronic kidney disease. It aims to learn more about what causes it and how to help those affected.
OdenseAges 18 years+ - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT06507449Enrolling by invitation
Treating Heavily Calcified Heart Blockages to Improve Microcirculation
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
KatowiceAges 18 years+ - NCT04115826Enrolling by invitation
Stones treatment comparison for chronic pancreas pain
This trial compares two ways to break and remove pancreatic duct stones in people with long-term pancreas pain caused by calcified stones. It looks to see which approach helps reduce pain more effectively and safely.
Aurora, ColoradoAges 18–89
Hear when a new Calcification trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for calcification?
- Yes. Clin2 currently lists 66 recruiting calcification studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a calcification trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a calcification trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.