Clinical trials
Coronary Calcification clinical trials
Below are recruiting coronary calcification clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05346068Recruiting
Compare two balloon types for calcium-heavy blocked heart arteries
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
LucerneAges 18 years+ - NCT06194526Enrolling by invitation
Blood test to measure heart artery plaque
This study is testing whether a new blood test can detect the amount of plaque buildup in your heart arteries compared to what a CT scan shows. It may help people with known or suspected coronary artery disease get a simpler, faster way to check their heart health.
Ciudad Autónoma de Buenos Aire, Buenos Aires F.D.Ages 18–75 - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT07703033Recruiting
Heart Impact Study for Breast Cancer Radiotherapy
This study looks at how information about the heart may affect treatment decisions for people receiving radiation therapy for breast cancer. It aims to help reduce heart-related side effects from treatment.
CopenhagenAges 35 years+ - NCT07277114Recruiting
Drug balloon vs stent for hardened arteries after special preparation
This trial compares two treatments for severely calcified coronary arteries: a drug-coated balloon (DCB) and a drug-eluting stent (DES). It is for people who have already had a procedure to crack or soften the calcium (like rotational atherectomy), and whose blood flow looks good afterward.
ShanghaiAges 18 years+ - NCT04889053Recruiting
CT heart scan study in adults with type 2 diabetes
This trial uses a low-dose CT scan of the heart’s arteries to measure coronary artery calcification in people with type 2 diabetes. It aims to better understand heart calcium buildup and may help improve risk assessment for people with diabetes.
HengyangAges 18 years+ - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06736665Recruiting
Comparing two ways to treat hardened calcium in heart arteries
This trial compares two techniques (orbital atherectomy and intravascular lithotripsy) to break up tough calcium deposits in the heart's arteries that can block blood flow. If you have a calcified nodule and are having a non-emergency procedure to open a blocked artery, this study may help guide which method works best.
Alicante, AlicanteAges 18 years+ - NCT06075602Recruiting
Complex and calcified coronary artery disease: a registry study
This study watches how people with complex or calcified heart artery disease are treated (with stents or bypass surgery) and how they do over time. It aims to learn which treatments work best for tough blockages.
Lucerne, Canton of LucerneAges 18 years+ - NCT04988685Recruiting
Heart artery balloon treatment registry study for adults
This study follows adults with blocked heart arteries who are treated using a special type of balloon (drug-coated balloon) during a procedure. It aims to track real-world outcomes to better understand how well this treatment works for people with new blockages or previously treated vessel narrowing.
Lucerne, Canton of LucerneAges 18 years+ - NCT05800002Recruiting
IVUS-guided stent placement for badly calcified heart arteries
This trial studies a heart procedure that uses a special camera to guide where to place a drug-coated stent in an artery with heavy calcium. It may help improve how well the stent fits and works for people with certain types of coronary artery blockages.
Nanjing, JiangsuAges 18 years+ - NCT06507449Enrolling by invitation
Treating Heavily Calcified Heart Blockages to Improve Microcirculation
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
KatowiceAges 18 years+ - NCT07000045Recruiting
Shock wave vs drill for hard calcium in heart arteries
This study tests a new way to break up hard calcium deposits in heart arteries using shock waves (lithotripsy), with or without a special drill (rotational atherectomy), before placing a stent. It may help people with severely calcified blockages that are hard to treat with standard methods.
New York, New YorkAges 18 years+ - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT07400406Recruiting
A new MRI test to see calcified heart arteries
This trial tests a special MRI using a contrast agent called ferumoxytol to better see calcium buildup in heart arteries. It may help people who need a coronary angiogram and have some calcium visible on a prior CT scan.
Nanjing, JiangsuAges 18–75 - NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT06577038Enrolling by invitation
Registry for a new heart artery treatment
This study tracks how well a new treatment called intravascular lithotripsy works for opening up hardened heart arteries. If you're having this procedure, joining the registry helps doctors learn more about its benefits.
BrusselsAges 18 years+ - NCT06235112Recruiting
AI Screening for Heart Calcium from Chest CT Scans
This research study uses an artificial intelligence program to screen old chest CT scans for calcium buildup in the heart arteries. If you are between 40 and 75 and have had a chest CT in the last 3 years, this may help identify if you are at risk for heart disease so you can take steps to prevent it.
Boston, MassachusettsAges 40–75 - NCT06414551Recruiting
Calcium on CT scan and heart blockage procedure outcomes
This study looks at whether calcium buildup seen on a heart CT scan affects the success of opening a completely blocked artery. It may help guide future treatment for people with similar blockages.
Birmingham, West MidlandsAges 18 years+ - NCT06631755Recruiting
How calcium affects stent healing: an imaging study
This study looks at how calcium buildup in artery walls affects how well a stent heals. Doctors will use special imaging (OCT) right after stent placement and again a month later to check the healing of the tiny metal struts.
BarcelonaAges 18 years+ - NCT07510438Recruiting
Pulse IVL treatment for hardened arteries in the heart
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries, making them easier to open. It may help people with coronary artery disease who have not had prior stents or recent heart attacks.
Sydney, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for coronary calcification?
- Yes. Clin2 currently lists 23 recruiting coronary calcification studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary calcification trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary calcification trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.