Clinical trials
Calcification clinical trials
Below are recruiting calcification clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04889053Recruiting
CT heart scan study in adults with type 2 diabetes
This trial uses a low-dose CT scan of the heart’s arteries to measure coronary artery calcification in people with type 2 diabetes. It aims to better understand heart calcium buildup and may help improve risk assessment for people with diabetes.
HengyangAges 18 years+ - NCT07756307Recruiting
Shock wave therapy for calcium deposits in the shoulder
This trial tests whether a non-invasive treatment called shock wave therapy can reduce pain and improve function in people with calcium deposits in the shoulder tendon. It uses sound waves to break up the deposits, which may relieve pain and help you move better.
Taipei, TaipeiAges 20–70 - NCT05662111RecruitingPhase 2
Etidronate treatment for brain calcifications in Fahr disease
This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.
Utrecht, UtrechtAges 18 years+ - NCT04010201Recruiting
Study of brain calcium deposits on CT scans
This study looks at people who have extra calcium deposits in the brain seen on a CT scan (and also includes some relatives and healthy volunteers). It aims to better understand who has brain calcification and what it may mean, using research visits and scan-based measurements.
Fuzhou, FujianAges Any age - NCT07277114Recruiting
Drug balloon vs stent for hardened arteries after special preparation
This trial compares two treatments for severely calcified coronary arteries: a drug-coated balloon (DCB) and a drug-eluting stent (DES). It is for people who have already had a procedure to crack or soften the calcium (like rotational atherectomy), and whose blood flow looks good afterward.
ShanghaiAges 18 years+ - NCT07703033Recruiting
Heart Impact Study for Breast Cancer Radiotherapy
This study looks at how information about the heart may affect treatment decisions for people receiving radiation therapy for breast cancer. It aims to help reduce heart-related side effects from treatment.
CopenhagenAges 35 years+ - NCT05346068Recruiting
Compare two balloon types for calcium-heavy blocked heart arteries
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
LucerneAges 18 years+ - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT06414551Recruiting
Calcium on CT scan and heart blockage procedure outcomes
This study looks at whether calcium buildup seen on a heart CT scan affects the success of opening a completely blocked artery. It may help guide future treatment for people with similar blockages.
Birmingham, West MidlandsAges 18 years+ - NCT06418698Recruiting
Brain artery calcium and clot removal outcomes
This study looks at whether calcium buildup in brain arteries affects how well clot removal (mechanical thrombectomy) works for stroke patients. You may be able to join if you have a large artery blockage, a CT scan was done, and you are having the clot removal procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT07033507Recruiting
Scoring method for breast lesions seen on MRI
This study tests if adding a special MRI measurement (diffusion coefficient) and micro-calcifications to a standard scoring system (Kaiser score) can better tell which breast lesions are cancerous. It could help avoid unnecessary biopsies.
Al MansurahAges Any age - NCT07409818Recruiting
Shoulder calcific tendinitis treatment study
This trial tests a new way to classify calcium deposits in the shoulder tendon using MRI, which may help doctors choose the best treatment. It is for people who are having surgery for this condition.
Istanbul, ZeytinburnuAges Any age - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT06194526Enrolling by invitation
Blood test to measure heart artery plaque
This study is testing whether a new blood test can detect the amount of plaque buildup in your heart arteries compared to what a CT scan shows. It may help people with known or suspected coronary artery disease get a simpler, faster way to check their heart health.
Ciudad Autónoma de Buenos Aire, Buenos Aires F.D.Ages 18–75 - NCT07510438Recruiting
Pulse IVL treatment for hardened arteries in the heart
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries, making them easier to open. It may help people with coronary artery disease who have not had prior stents or recent heart attacks.
Sydney, New South WalesAges 18 years+ - NCT05145478Recruiting
Real-world outcomes after Shockwave treatment for blocked leg artery
This study follows what happens in real life after using Shockwave’s device (intravascular lithotripsy) to treat a hard, calcified blockage in the common femoral artery, then completing standard treatment. It may help doctors understand which patients benefit and what results to expect.
New Haven, ConnecticutAges 18 years+ - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT06577038Enrolling by invitation
Registry for a new heart artery treatment
This study tracks how well a new treatment called intravascular lithotripsy works for opening up hardened heart arteries. If you're having this procedure, joining the registry helps doctors learn more about its benefits.
BrusselsAges 18 years+ - NCT05551780Recruiting
Study for treating calcium blockages in leg artery disease
This trial tests a treatment approach for certain long-lasting, calcium-heavy blockages in the leg arteries that have no normal blood flow past the blockage. If you have these “total occlusions” and symptoms like walking pain or critical limb symptoms, this study may offer a new way to open the artery and restore blood flow.
Fort Lauderdale, FloridaAges 19 years+ - NCT07400406Recruiting
A new MRI test to see calcified heart arteries
This trial tests a special MRI using a contrast agent called ferumoxytol to better see calcium buildup in heart arteries. It may help people who need a coronary angiogram and have some calcium visible on a prior CT scan.
Nanjing, JiangsuAges 18–75
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Common questions
- Are there clinical trials for calcification?
- Yes. Clin2 currently lists 66 recruiting calcification studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a calcification trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a calcification trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.