Clinical trials
Calcification clinical trials
Below are recruiting calcification clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04889053Recruiting
CT heart scan study in adults with type 2 diabetes
This trial uses a low-dose CT scan of the heart’s arteries to measure coronary artery calcification in people with type 2 diabetes. It aims to better understand heart calcium buildup and may help improve risk assessment for people with diabetes.
HengyangAges 18 years+ - NCT04010201Recruiting
Study of brain calcium deposits on CT scans
This study looks at people who have extra calcium deposits in the brain seen on a CT scan (and also includes some relatives and healthy volunteers). It aims to better understand who has brain calcification and what it may mean, using research visits and scan-based measurements.
Fuzhou, FujianAges Any age - NCT05346068Recruiting
Compare two balloon types for calcium-heavy blocked heart arteries
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
LucerneAges 18 years+ - NCT07756307Recruiting
Shock wave therapy for calcium deposits in the shoulder
This trial tests whether a non-invasive treatment called shock wave therapy can reduce pain and improve function in people with calcium deposits in the shoulder tendon. It uses sound waves to break up the deposits, which may relieve pain and help you move better.
Taipei, TaipeiAges 20–70 - NCT07715279RecruitingPhase 2
Vericiguat for slowing aortic valve calcium buildup
This trial tests if the drug vericiguat can slow down the buildup of calcium in the aortic valve, which causes it to narrow and stiffen. If you have mild-to-moderate aortic valve stenosis and meet the other criteria, this study may help protect your valve from getting worse.
Chengdu, SichuanAges 35–80 - NCT07703033Recruiting
Heart Impact Study for Breast Cancer Radiotherapy
This study looks at how information about the heart may affect treatment decisions for people receiving radiation therapy for breast cancer. It aims to help reduce heart-related side effects from treatment.
CopenhagenAges 35 years+ - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07409818Recruiting
Shoulder calcific tendinitis treatment study
This trial tests a new way to classify calcium deposits in the shoulder tendon using MRI, which may help doctors choose the best treatment. It is for people who are having surgery for this condition.
Istanbul, ZeytinburnuAges Any age - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT07277114Recruiting
Drug balloon vs stent for hardened arteries after special preparation
This trial compares two treatments for severely calcified coronary arteries: a drug-coated balloon (DCB) and a drug-eluting stent (DES). It is for people who have already had a procedure to crack or soften the calcium (like rotational atherectomy), and whose blood flow looks good afterward.
ShanghaiAges 18 years+ - NCT07033507Recruiting
Scoring method for breast lesions seen on MRI
This study tests if adding a special MRI measurement (diffusion coefficient) and micro-calcifications to a standard scoring system (Kaiser score) can better tell which breast lesions are cancerous. It could help avoid unnecessary biopsies.
Al MansurahAges Any age - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT06418698Recruiting
Brain artery calcium and clot removal outcomes
This study looks at whether calcium buildup in brain arteries affects how well clot removal (mechanical thrombectomy) works for stroke patients. You may be able to join if you have a large artery blockage, a CT scan was done, and you are having the clot removal procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT06194526Enrolling by invitation
Blood test to measure heart artery plaque
This study is testing whether a new blood test can detect the amount of plaque buildup in your heart arteries compared to what a CT scan shows. It may help people with known or suspected coronary artery disease get a simpler, faster way to check their heart health.
Ciudad Autónoma de Buenos Aire, Buenos Aires F.D.Ages 18–75 - NCT05662111RecruitingPhase 2
Etidronate treatment for brain calcifications in Fahr disease
This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.
Utrecht, UtrechtAges 18 years+ - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT02808572Recruiting
Blood and urine tests to study heart risk in kidney disease
This study looks for new markers in blood or urine that may help explain heart (cardiovascular) risk in people with chronic kidney disease. It may help doctors better predict risk, especially in those not yet on dialysis.
MontpellierAges 18–95 - NCT02813642Recruiting
Study of heart risk in people starting dialysis
This study looks at heart (cardiovascular) risk factors in people who are just starting dialysis for chronic kidney failure. It may help doctors better understand what heart-related issues to watch for early during dialysis.
Castelnau-le-LezAges 18–90 - NCT05275088Recruiting
Transcatheter valve replacement for badly calcified heart valves
This trial tests Prizvalve, a catheter-based procedure to replace a severely damaged “atrioventricular” valve in people at high risk from open-heart surgery. It may help reduce symptoms caused by valve narrowing or leaking when traditional surgery is not a good option.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06153407Recruiting
Genetic test for early valve disease in bicuspid aortic valve
This study looks at how genes may affect the risk of calcium buildup in the aortic valve in people with a bicuspid aortic valve. By joining, you help researchers find better ways to predict and manage this heart condition.
SeoulAges 19–80 - NCT07865936Recruiting
Heart health check for fatty liver disease patients
This study looks at heart health in people with fatty liver disease (MASLD) by measuring calcium in the heart's arteries with a special scan, to see if they are at risk for heart problems.
Bangkok, BangkoknoiAges 35–75
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Common questions
- Are there clinical trials for calcification?
- Yes. Clin2 currently lists 65 recruiting calcification studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a calcification trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a calcification trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.