Clinical trials
Cancer Prevention clinical trials
Below are recruiting cancer prevention clinical trials, each written for real people, not researchers. We’re tracking 290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06337695RecruitingPhase 2/Phase 3
Preventing immunotherapy-related diarrhea in advanced cancer
This study tests whether vedolizumab, a drug that reduces gut inflammation, can prevent diarrhea caused by immunotherapy (a type of cancer treatment). It is for adults with advanced melanoma, lung, or kidney cancer who have a stool marker of inflammation early in treatment.
Calgary, AlbertaAges 18 years+ - NCT05910294Recruiting
Preventing and improving sexual health in early breast cancer
This study looks at ways to prevent and treat sexual discomfort in people with hormone-receptor positive breast cancer. It targets women who are not having current vaginal dryness or pain related to lower estrogen, and may help protect sexual comfort during cancer-related hormone treatment.
Basking Ridge, New JerseyAges 18 years+ - NCT07498517RecruitingPhase 2
Single dose of gruticibart to prevent blood clot complications
This trial tests if a single dose of a drug called gruticibart can help prevent blood clots caused by a central line (a special IV tube) inserted for cancer treatment. It may be an option for adults starting therapy that requires this type of IV access.
Portland, OregonAges 18 years+ - NCT06354712RecruitingPhase 2
Can N-acetylcysteine prevent mouth sores during radiation?
This study tests whether a medicine called N-acetylcysteine (NAC) can prevent mouth sores caused by radiation therapy for head and neck cancer. If you are starting radiation, this trial may help protect your mouth from painful side effects.
Al MansurahAges 18–80 - NCT06904235RecruitingPhase 2
A trial testing IV NEPA to prevent nausea and vomiting in kids getting strong chemo
This trial tests a medicine called IV NEPA (fosnetupitant/palonosetron) to prevent nausea and vomiting in children who are receiving strong chemotherapy. Patients will receive at least one cycle of chemotherapy that is highly likely to cause these side effects.
AthensAges birth–18 years - NCT06823440Recruiting
Preventing nerve damage from chemo with compressive therapy
This trial tests if wearing compressive therapy (like special sleeves or stockings) during weekly paclitaxel chemotherapy can prevent nerve damage (peripheral neuropathy) in breast cancer patients. It is for people who have not yet had nerve issues or diabetes.
BrnoAges 18–70 - NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Birmingham, AlabamaAges Up to 39 years - NCT06492070RecruitingPhase 2
Cooling therapy with or without cilostazol to prevent nerve damage from paclitaxel
This study tests whether cooling your hands and feet during chemotherapy, with or without the medicine cilostazol, can help prevent nerve damage (numbness, tingling, or pain) caused by the drug paclitaxel. It is for people with gynecologic cancers who are about to start or have just finished paclitaxel treatment.
Atlanta, GeorgiaAges 18 years+ - NCT05216328RecruitingPhase 4
Preventing opioid-related constipation in advanced cancer
This trial tests whether starting a laxative right away can prevent constipation caused by pain medications called opioids. It's for people with advanced cancer who are beginning opioid pain treatment and aims to improve comfort and quality of life.
Almere Stad, FlevolandAges 18 years+ - NCT03010150Recruiting
Blood tests and swallowing exercise check-ins for head and neck cancer
This study looks at whether giving swallowing exercises and checking in with questionnaires can help people with metastatic (spreading to neck lymph nodes) head and neck cancers do the exercises correctly. It also uses blood tests to better understand adherence and progress over time.
Houston, TexasAges 18 years+ - NCT06265558Recruiting
Vacuum dressing to prevent wound problems after breast cancer surgery
This study tests a special vacuum dressing (negative pressure therapy) to prevent wound problems after complex breast cancer surgery. It's for women who have risk factors for poor healing and are having a mastectomy with immediate reconstruction or a certain breast-conserving surgery.
Dijon, Côte d'OrAges 18 years+ - NCT06639178Recruiting
Cream to prevent hand-foot syndrome from capecitabine in breast cancer
This trial tests whether a special cream containing N-acetylcysteine and urea can prevent the painful hand-foot syndrome often caused by the chemotherapy drug capecitabine. If you have breast cancer and are about to start capecitabine, this study may help reduce side effects.
Aviano, PordenoneAges 18 years+ - NCT07295457Recruiting
Exercise to prevent pain from hormone therapy in breast cancer
This trial tests whether starting a gentle exercise program early can help prevent or reduce joint and muscle pain caused by aromatase inhibitors (a common breast cancer medicine). It is for women with hormone-sensitive breast cancer who are not yet experiencing severe pain from their treatment.
LyonAges 18–75 - NCT04997096Recruiting
Exercise during chemo to prevent weakness from low movement
This study tests whether a structured exercise program during chemotherapy can help prevent physical decline (“immobility,” like getting weaker or moving less) in people with certain ovarian or endometrial cancers. If you’re eligible, you may be guided to exercise while receiving standard chemo, and you’ll have blood tests to track changes.
Boston, MassachusettsAges 18 years+ - NCT04067830RecruitingPhase 2
Breathing muscle training before lung surgery to prevent complications
This trial tests whether training your breathing muscles before lung surgery can reduce lung problems after surgery in people with stage I to IIIb lung cancer. It may help improve breathing and lower the chance of post-surgery lung complications.
Buffalo, New YorkAges 18 years+ - NCT06847555RecruitingPhase 1/Phase 2
Taurine cream to prevent skin burns from radiation in breast cancer
This trial tests if a taurine cream applied to the skin can prevent or reduce the painful skin reactions caused by radiation therapy for breast cancer. It may offer a simple way to protect your skin during treatment.
Jinan, ShandongAges 18 years+ - NCT07694726Recruiting
Vein repair during neck surgery to prevent lymphedema
This study tests whether repairing veins during head and neck cancer surgery helps prevent lymphedema (painful swelling) after treatment. It may help patients who are having lymph node removal and will receive radiation afterward.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07559877RecruitingPhase 3
Chlorhexidine spray to prevent radiation skin damage in throat cancer
This study tests whether a chlorhexidine spray (an antiseptic liquid) can prevent or reduce skin damage caused by radiation therapy in people being treated for nasopharyngeal cancer (cancer in the back of the nose/throat). Radiation dermatitis—painful redness and irritation of the skin—is a common side effect, and this spray may help protect your skin during treatment.
Nanchang, JiangxiAges 18–75 - NCT07024433Recruiting
No-breathing-tube surgery for early lung cancer
This study tests a special 'tubeless' anesthesia technique — avoiding breathing tubes during surgery — for people with early-stage lung cancer. The goal is to see if it reduces lung problems after the operation.
Fuzhou, FujianAges 18–70 - NCT07380646RecruitingPhase 2
Leucogen to prevent low white blood cells from ribociclib in early breast cancer
This trial tests if Leucogen can prevent neutropenia (low white blood cells) caused by ribociclib, a targeted therapy for hormone receptor-positive, HER2-negative early breast cancer. It may help you stay on treatment without delays or dose reductions.
Hangzhou, ZhejiangAges 18 years+ - NCT07447050RecruitingPhase 2
Riluzole to Prevent Chemo-Related Cognitive Problems
This pilot study tests whether the drug riluzole can help prevent the thinking and memory problems (often called 'chemobrain') that some people experience during chemotherapy. If you are about to start a chemo regimen containing an anthracycline or platinum drug, you may be able to join.
Orange, CaliforniaAges 18 years+ - NCT07774520RecruitingPhase 2
Lower dose of lazertinib plus magnesium to prevent nerve damage in advanced lung cancer
This trial tests a lower starting dose of the targeted therapy drug lazertinib combined with magnesium supplements to prevent a common side effect (peripheral neuropathy) in people with advanced lung cancer caused by certain EGFR mutations. The goal is to see if this approach keeps the drug effective while reducing nerve damage symptoms like numbness or tingling.
Seoul, Gang-nam GuAges 19 years+ - NCT06023212RecruitingPhase 1/Phase 2
Tranexamic acid to prevent bleeding in spine surgery for lung cancer
This trial tests if a medicine called tranexamic acid can help reduce bleeding during surgery for lung cancer that has spread to the spine. It may be an option if you have a single tumor in your spine and are having separation surgery.
Hangzhou, ZhejiangAges 10–80 - NCT07300735Recruiting
Can citrus compounds or allergy meds prevent G-CSF bone pain?
This study tests whether taking a combination of two natural compounds (diosmin and hesperidin) similar to those from citrus fruits, or the allergy medicine loratadine, can prevent or reduce bone pain caused by G-CSF injections—a common treatment to boost white blood cells in people with blood cancers.
AlexandriaAges 18–65
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Common questions
- Are there clinical trials for cancer prevention?
- Yes. Clin2 currently lists 290 recruiting cancer prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.