Clinical trials
Cancer-related Pain clinical trials
Below are recruiting cancer-related pain clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06749964Recruiting
Personalized internet CBT for cancer-related pain
This trial tests a personalized internet-based cognitive behavioral therapy (CBT) program designed to help people with cancer-related chronic pain. It aims to improve how you cope with pain and daily life challenges.
LundAges 18 years+ - NCT06830018Recruiting
New megestrol for advanced stomach or colon cancer with fatigue
This study tests a new form of megestrol (a medicine that can boost appetite and energy) for people with advanced stomach or colorectal cancer who also have fatigue and poor appetite. It is given as a first treatment, meaning you haven't had chemotherapy yet for your advanced cancer.
Shenyang, LiaoningAges 18–75 - NCT06287515RecruitingPhase 1
Radiation to the pituitary gland for cancer pain
This study tests a focused radiation treatment on a small gland in the brain to see if it can relieve cancer-related pain that hasn't been controlled by standard treatments like painkillers or other therapies. It may help patients whose pain limits their daily life.
Houston, TexasAges 18 years+ - NCT07636382Recruiting
Radiation to relieve cancer-related belly pain from celiac plexus involvement
This trial tests a focused radiation treatment called stereotactic body radiotherapy (SBRT) to target pain from cancer affecting the celiac plexus—a bundle of nerves in the upper abdomen. The goal is to relieve severe, persistent pain without surgery.
Toronto, OntarioAges 18 years+ - NCT07711626Recruiting
Foot massage and ear stimulation for head and neck cancer symptoms
This study tests whether foot massage (reflexology) and a mild nerve-stimulation device on the ear can help reduce side effects during chemotherapy and radiation for head and neck cancer.
Hualien CityAges 30–75 - NCT05440227RecruitingPhase 2
PG2 shots to reduce moderate to severe breast cancer fatigue
This Phase 2 trial tests whether PG2 injections can safely reduce moderate to severe fatigue in people receiving chemotherapy for locally advanced, recurrent, or metastatic breast cancer. If you qualify, you may be asked to complete questionnaires and follow study plans for about 8 weeks.
TaipeiAges 20 years+ - NCT06200181RecruitingPhase 3
Olanzapine for opioid misuse in cancer pain
This study tests if a medication called olanzapine can help reduce cravings and misuse of opioid pain medicines in people with cancer pain. You would take olanzapine or a placebo daily for a few weeks while continuing your usual care.
Houston, TexasAges 18 years+ - NCT06498037RecruitingPhase 4
Better fentanyl dosing for cancer pain
This trial is testing a new way to give fentanyl under the skin for cancer-related pain. The goal is to find the right dose quickly and safely to make sure you get enough pain relief.
Rotterdam, South HollandAges 18–120 - NCT07408193RecruitingEarly Phase 1
Lidocaine and ketamine for severe cancer pain not helped by opioids
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
Athens, AtticaAges 18 years+ - NCT07003763Recruiting
Electroacupuncture for depression in cancer patients
This trial tests whether electroacupuncture can help treat depression caused by cancer or its treatments. It may be a safe option for people who have not tried acupuncture before and are not currently receiving active cancer treatments.
ShanghaiAges 18–75 - NCT07038434Recruiting
Using artificial intelligence to measure pain in chronic pain patients
This study uses artificial intelligence to better understand and measure pain in people with chronic pain. The goal is to develop smarter ways to assess pain automatically, which could lead to better treatment.
Salerno, ItalyAges 18 years+ - NCT07117032RecruitingPhase 1
Radiation therapy for cancer-related stomach pain
This trial tests a type of radiation therapy (SBRT) to treat severe stomach pain caused by cancer pressing on nerves near the stomach. It aims to provide pain relief without the need for a standard nerve block procedure.
Cleveland, OhioAges 18 years+ - NCT07262632Recruiting
Cancer pain and AI assessment study
This study builds a database of videos and voice recordings from people with cancer, both with and without pain. The goal is to train artificial intelligence (AI) to automatically recognize pain, which could help doctors better manage it in the future.
Rotterdam, South HollandAges 18 years+ - NCT07326137Recruiting
Pain relief and first-line treatment for advanced bile duct or pancreatic cancer
This study tests combining standard first-line cancer therapy with a nerve block to reduce pain in people with advanced bile duct or pancreatic cancer. It aims to see if this combination can improve pain control and quality of life.
Wuhan, HubeiAges Any age - NCT07402577Recruiting
Pain and opioid use in young sarcoma survivors
This study looks at pain and opioid use in adolescents and young adults who have had sarcoma. It uses a smartphone app to track symptoms over 3 months to better understand cancer-related pain.
Buffalo, New YorkAges 12–70 - NCT07669519RecruitingPhase 3
Supplement for fatigue in stage IV colon cancer
This study tests an oral supplement (Nuvastatic) to see if it helps reduce fatigue in people with stage IV colon cancer who are starting chemotherapy for the first time. If you are 18–65 and have fatigue that is affecting you, this trial might offer a way to feel better.
Srikakulam, Andhra PradeshAges 18–65 - NCT05869682RecruitingPhase 2
Bright light therapy for fatigue and depression in prostate cancer
This Phase 2 study tests whether a “bright white light” intervention can reduce cancer-related fatigue and depression in people with advanced prostate cancer receiving hormone-based treatment. If it works, it could improve day-to-day well-being while you’re on standard cancer therapies.
Duarte, CaliforniaAges 60 years+ - NCT07616648Recruiting
How Opioid Pain Drugs Affect Sleep and Mood in Cancer Patients
This study examines how opioid medications (strong pain relievers) impact sleep quality and emotional well-being in cancer patients with moderate to severe pain. Researchers will track your sleep patterns and mood to better understand these side effects.
HangzhouAges 18–75 - NCT07308951Recruiting
Electrical acupoint stimulation for chronic cancer pain relief
This trial tests if a small, patient-controlled device that sends mild electrical pulses to acupoints (like acupuncture without needles) can improve quality of life for people with ongoing cancer pain. It may offer a drug-free way to manage pain at home.
Zhejiang, HangzhouAges 18–80 - NCT07265557Recruiting
Comparing two pain plans after orthopedic surgery
This trial compares two different pain medication plans after major orthopedic surgery. It aims to find which plan helps you recover with less pain and fewer side effects.
Boston, MassachusettsAges 18 years+ - NCT06008899Recruiting
Ultrasound-guided pulsed radiofrequency for cancer anal pain
This trial tests a treatment called pulsed radiofrequency applied through a small needle near the tailbone (caudal epidural) to see if it can help relieve cancer-related anal or perineal pain. It may be an option if you have this type of pain and are in reasonably good health aside from your cancer.
AsyutAges 18–60 - NCT05585788Recruiting
Opioid pain device test for cancer surgery patients
This study tests a device that helps you safely use opioid (strong pain) medicine after major cancer surgery. It may help improve post-surgery pain control while tracking how people use the medicine.
New York, New YorkAges 18–99 - NCT06395441RecruitingPhase 3
Wisconsin ginseng for cancer-related fatigue
This trial tests whether Wisconsin ginseng can help reduce fatigue in people who have had or are getting treatment for a solid tumor cancer. It aims to improve energy levels and quality of life.
Albert Lea, MinnesotaAges 18 years+ - NCT04721041Recruiting
Fecal microbiota transplant for gut side effects after cancer treatment
This trial tests a treatment called “washed microbiota transplant,” which transfers healthy gut bacteria to help relieve intestinal problems that started after cancer therapy. You might benefit if you’re an adult with certain ongoing stomach or bowel symptoms after standard cancer treatment, and your body is stable enough for the procedure.
Nanjing, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for cancer-related pain?
- Yes. Clin2 currently lists 27 recruiting cancer-related pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer-related pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer-related pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.