Clinical trials
Cancer Risk clinical trials
Below are recruiting cancer risk clinical trials, each written for real people, not researchers. We’re tracking 721 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07114653Recruiting
Study of POLE mutation in high-risk endometrial cancer
This trial looks at a specific genetic change called POLE mutation in women with endometrial cancer that has a high risk of coming back. It may help doctors understand who could benefit from different treatments.
Banqiao District, New TaipeiAges Any age - NCT06773871Recruiting
Exercise study for low-risk myeloid cancers and precursor conditions
This trial tests whether exercise is safe and feasible for people with low-risk myeloid cancers or certain bone marrow conditions. It aims to see if a supervised exercise program can be done without problems.
Copenhagen, DenmarkAges 18 years+ - NCT06499870RecruitingPhase 2
Study of two drugs with radiation for high-risk prostate cancer
This trial tests whether combining two hormone therapy drugs, relugolix and enzalutamide, with radiation therapy can help treat very high-risk prostate cancer. The goal is to see if this combination is safe and effective for men whose cancer has a high chance of coming back.
Chicago, IllinoisAges 18 years+ - NCT06482073Recruiting
Genetic testing for suspected lung cancer
This study looks at genetic changes in people with suspected or high-risk lung cancer. It aims to use those results to guide more personalized treatment decisions.
Rochester, MinnesotaAges 18 years+ - NCT06432985Recruiting
Smoking cessation coaching for veterans with cancer
This study tests a counseling program to help veterans who smoke quit smoking, especially those undergoing cancer treatment or lung cancer screening. It may improve health outcomes during cancer care.
San Francisco, CaliforniaAges 18 years+ - NCT06237179RecruitingPhase 1/Phase 2
Exercise program to reduce heart risk in prostate cancer
This study tests whether a supervised exercise program can help reduce heart disease risk in men with prostate cancer who are on hormone therapy. Participants will exercise at home or in a group and be monitored for heart health changes.
Richmond, VirginiaAges 40–85 - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT04290663RecruitingPhase 3
Radioiodine decision after thyroid surgery for intermediate-risk cancer
This study compares two approaches after thyroid surgery: giving radioactive iodine right away versus deciding based on follow-up test results. It aims to see which approach better helps people with intermediate-risk differentiated thyroid cancer.
Pointe à Pitre, GuadeloupeAges 18 years+ - NCT07468851RecruitingPhase 1/Phase 2
Study of HS-10566 for high-risk bladder cancer that hasn't spread into muscle
This study tests a new treatment called HS-10566 for people with a type of bladder cancer that has not reached the muscle layer and is considered high-risk, where the usual treatments have not worked or were not an option. It aims to control the cancer and avoid the need for removing the bladder.
BeijingAges 18 years+ - NCT05843877RecruitingPhase 3
Surgery choice and insulin islet transplant to prevent leaks
This Phase 3 trial studies a pancreatic surgery approach (pylorus-preserving Whipple or similar) and, in some cases, moving your insulin-making cells into your body to help prevent a dangerous post-surgery leak from the pancreas. It may help people who are considered high risk for this complication based on pancreas texture and duct size.
DresdenAges 18 years+ - NCT04333706RecruitingPhase 1/Phase 2
Sarilumab plus capecitabine for certain breast cancers
This trial studies whether adding sarilumab to capecitabine can shrink or control metastatic or high-risk breast cancer that lacks HER2 and is either triple-negative or hormone-resistant. It aims to find a safe dose first, then look at how well the treatment works compared with historical results.
Los Angeles, CaliforniaAges 18–99 - NCT06734156Recruiting
Gut microbiome study in colorectal cancer patients
This study looks at how bacteria and other microbes in your gut are linked to colorectal cancer risk and outcomes. By collecting stool samples from people newly diagnosed with colorectal cancer, researchers hope to find patterns that could improve understanding and future treatments.
Lisbon, Lisbon DistrictAges 40–74 - NCT06945172Recruiting
Comparing quality of life after prostate removal vs. focal HIFU for prostate cancer
This study compares how two treatments—total prostate removal or focal HIFU (a targeted ultrasound therapy)—affect quality of life in men with favorable intermediate-risk prostate cancer who are sexually active. It aims to help patients choose the best option for their lifestyle.
Quint-FonsegrivesAges 40–75 - NCT06310564Recruiting
SBRT for limited metastatic colorectal cancer
This trial tests whether focused radiation (SBRT) can treat 1 to 3 metastases in people with colorectal cancer that has spread but is still low or intermediate risk. It may be an option if you are starting first or second line systemic therapy and your primary tumor is under control.
Negrar, VeronaAges 18 years+ - NCT06629896Recruiting
Comparing contrast mammogram vs MRI for high-risk breast cancer surveillance
This trial compares two advanced imaging methods—contrast-enhanced mammography and MRI—to see which is better for detecting breast cancer early in women at high risk. If you are at high risk and have not had breast cancer before, this study could help guide your future screening.
Reggio Emilia, Italy/Reggio EmiliaAges 35–60 - NCT06408220Recruiting
Stomach cancer risk check for minority groups
This study checks if you are at high risk for stomach cancer. You will give blood samples and have a stomach exam (endoscopy) to look for early signs.
Duarte, CaliforniaAges 40–80 - NCT04700332RecruitingPhase 2
Test of PyL PET/CT for high-risk or returning prostate cancer
This Phase 2 study checks how well a scan called PyL PET/CT can help find prostate cancer that is high-risk or has come back by blood test. The goal is to improve how doctors detect spread and guide the next treatment steps.
Irvine, CaliforniaAges 18 years+ - NCT06385717Recruiting
ESD plus chemoradiotherapy for early esophageal cancer
This study tests whether combining radiation and chemotherapy after endoscopic removal of early-stage esophageal cancer can effectively treat the cancer without needing surgery. It may be an option for people whose cancer was removed with ESD but who want to avoid additional surgery.
Hangzhou, ZhejiangAges 18–75 - NCT07838207Recruiting
Molecular markers and outcomes in early-stage endometrial cancer
This study looks at women with certain high-risk types of endometrial cancer that have not spread into the muscle wall of the uterus. It aims to understand how these cancers behave and whether lymph node testing is needed, which could help guide treatment decisions.
Barcelona, BarcelonaAges 18 years+ - NCT07231627Recruiting
Using AI to improve prostate cancer detection from MRI
This trial tests whether an artificial intelligence (AI) program can help doctors decide when a prostate biopsy is needed. It is for men who have had a prostate MRI that shows either a low-risk (PIRADS 1-2) or uncertain (PIRADS 3) spot, along with a higher-than-normal PSA level. You may qualify if you have certain risk factors like a high PSA density, suspicious digital rectal exam, or family history of prostate cancer.
Little Rock, ArkansasAges 40 years+ - NCT06220435Recruiting
Radiation therapy for very high-risk localized prostate cancer
This trial tests radiation therapy for men with very high-risk prostate cancer that hasn't spread. It aims to see if targeting the tumor with radiation can help control the cancer in this highest risk group.
LundAges 18 years+ - NCT04938804Recruiting
One-time lung cancer screening with a low-dose chest CT
This study tests whether a one-time, low-dose chest CT scan can help find lung cancer early in certain people. You may be invited because of your age and location, and because you have not had recent related testing or symptoms.
Guangzhou, GuangdongAges 40–74 - NCT07398690Recruiting
MRI-guided approach for prostate cancer diagnosis
This trial tests if using MRI and a blood test called PHI can help decide who needs a prostate biopsy. It aims to avoid unnecessary biopsies while still catching cancer early.
SeoulAges 20 years+ - NCT02775461Recruiting
Registry for people at high risk for pancreatic cancer
This study is a registry (a way to track health over time) for people with a strong family history or certain inherited genetic risks for pancreatic cancer. It may help doctors learn how best to monitor and protect high-risk people, and to see who benefits most from follow-up.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for cancer risk?
- Yes. Clin2 currently lists 721 recruiting cancer risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.