Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,086 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04845828Recruiting
Sentinel node biopsy versus full node removal in early uterine cancer
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
SeoulAges 20–80 - NCT05257434Recruiting
Body composition test after liver, bile duct, or pancreas cancer surgery
This study looks at how well people do after surgery for liver, bile duct, or pancreas cancer, using a body composition test (the “inBody” test). It may help doctors understand which body changes after surgery are linked to better or worse recovery.
KochiAges 18–90 - NCT04787354RecruitingPhase 3
Choosing the best length of oxaliplatin after stomach surgery
This trial tests whether giving oxaliplatin for a shorter or longer time works best after curative surgery for stage II–III stomach (or stomach–esophagus junction) cancer. It aims to improve outcomes while balancing side effects from chemotherapy.
Gyeonggi-doAges 19 years+ - NCT04480203Recruiting
Digital coping tools after new breast cancer diagnosis
This trial tests two online programs designed to help people cope after being diagnosed with breast cancer. It may help you manage stress and emotions during treatment or recovery.
OsloAges 20–69 - NCT05201430RecruitingPhase 3
FOLFOXIRI vs CapeOX before surgery for locally advanced rectal cancer
This trial compares two chemotherapy plans given before rectal cancer surgery to see which helps more people and works better for disease control. If you have locally advanced rectal cancer and have not had treatment yet, this study may be an option.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04991948RecruitingPhase 1
Testing pembrolizumab after CYAD-101 plus FOLFOX in colon cancer
This early-phase study tests whether adding pembrolizumab after CYAD-101 and FOLFOX chemotherapy can help treat metastatic colon or rectal cancer. It is mainly looking for safety and signs of how well the treatment works in people whose cancer has not responded to prior therapy.
Jacksonville, FloridaAges 18 years+ - NCT05240950RecruitingPhase 1
CAR-T cell therapy for colorectal cancer in the liver
This Phase 1 study tests an anti-CEA CAR-T cell treatment for people whose colorectal cancer spread to the liver but has been surgically removed with no visible remaining tumor. It aims to see if the treatment can better prevent the cancer from coming back, especially when early warning tests suggest leftover cancer cells.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT03676348Recruiting
Quality of life study around thyroid surgery
This study looks at how thyroid cancer—or thyroid tumors that may be cancer—affect your quality of life before and after surgery. It may help doctors understand what patients experience and how treatment planning could be better.
OsloAges 18 years+ - NCT04976296Recruiting
Monitoring minimal residual disease after lung cancer surgery
This study checks whether a special blood/tissue test called MRD (minimal residual disease, meaning tiny leftover cancer signals) can help monitor lung cancer after surgery. It may help doctors spot relapse earlier after your tumor has been fully removed.
Guangzhou, GuangdongAges 18 years+ - NCT05292742RecruitingPhase 2
Continue targeted breast cancer therapy or switch to a new combo
This Phase 2 study compares two treatment plans after breast surgery when cancer did not fully disappear before surgery. It tests whether adding trastuzumab, pyrotinib, and capecitabine works better than continuing the original targeted therapy.
Fuzhou, FujianAges 18–75 - NCT05291728Recruiting
Screening for early stomach cancer in Shaanxi
This trial is a community screening program to look for early stomach cancer in adults in Shaanxi. It may help doctors find cancer earlier, when treatment can be more effective.
Xi'an, ShaanxiAges 20 years+ - NCT04037956Recruiting
No-tube surgery versus usual laparoscopy for rectosigmoid cancer
This trial compares two surgical approaches to remove rectosigmoid cancer: a “tubeless” method versus standard laparoscopic surgery. It aims to see which approach works better and is easier or safer for recovery.
Guangzhou, GuangdongAges 18–75 - NCT05314803Recruiting
Yoga program for young adults affected by cancer
This study tests whether yoga can help young adults living with cancer feel better and function more comfortably. You may join even if you’re currently getting treatment or have finished treatment, as long as it’s safe for you to do yoga.
Calgary, AlbertaAges 18 years+ - NCT04894188Recruiting
Hormone plus radiation before prostate surgery for high-risk cancer
This trial studies giving hormone treatment and radiation before prostate surgery to treat high-risk, locally advanced prostate cancer. It aims to improve cancer control by shrinking or controlling the tumor before removing it.
Douliu City/Huwei Township, Yunlin CountyAges 20–75 - NCT05326295Recruiting
Breast cancer study using tumor cells in blood
This trial checks whether a blood test that looks at tumor cells can help guide treatment for people with breast cancer. If you join, your care team will follow your responses over time to see if this “phenotype surveillance” approach is useful.
Changsha, HunanAges 18–75 - NCT04938986Recruiting
Testing a tumor marker to predict colon cancer relapse risk
This study looks at whether a lab test on your tumor can better predict the chance that non-metastatic colon cancer will come back after surgery. Researchers will compare relapse risk using the Immunoscore® test to help guide follow-up and treatment decisions.
MarseilleAges 18–80 - NCT05314114Recruiting
Skipping underarm surgery for some breast cancers after chemotherapy
This trial studies whether it’s safe to skip removing underarm lymph nodes (axillary surgery) for people with certain breast cancers after they respond to “NACT,” a type of chemotherapy. It also uses planned breast-conserving surgery and whole-breast radiation to see if outcomes stay similar while reducing surgery-related side effects.
Beijing, Beijing MunicipalityAges 18–70 - NCT03753243RecruitingPhase 2
Pembrolizumab and hormone blocker before prostate surgery
This Phase 2 trial studies whether pembrolizumab plus a hormone “androgen axis” blocker taken before prostate surgery can improve outcomes for people with high-risk, non-metastatic prostate cancer. It’s designed for patients who are planning prostate removal with an extended lymph node dissection.
Portland, OregonAges 18 years+ - NCT05334459Recruiting
Radiation and medicines after surgery for new metastatic breast cancer
This trial looks at giving radiation and anti-cancer medicines after surgery to treat newly diagnosed (de novo) metastatic breast cancer. It may help patients by improving local control of the breast area while also treating cancer throughout the body.
AnkaraAges 18–80 - NCT05367206RecruitingPhase 3
Tested chemotherapy before chemoradiation for advanced cervical cancer
This trial compares two treatment plans for stage IIIC cervical cancer: giving chemotherapy first, then chemoradiation, versus going straight to chemoradiation. It may help doctors see which approach works better for shrinking the cancer before and during radiation.
Guangzhou, GuangdoneAges 18–70 - NCT05378919RecruitingPhase 2
Testing new pre-surgery treatment for locally advanced rectal cancer
This Phase 2 trial compares a pre-surgery (neoadjuvant) treatment plan versus the standard plan for people with stage II–III rectal cancer. The goal is to see which approach works better and is safe before surgery.
KaunasAges 18 years+ - NCT05420454RecruitingPhase 4
Neoadjuvant treatment for breast cancer before surgery
This trial tests a treatment given before breast surgery to shrink breast cancer and improve outcomes based on your tumor type. Your eligibility depends on tumor size/stage, hormone and HER2 markers, and overall health checks.
Hangzhou, ZhejiangAges 18 years+ - NCT04079049RecruitingPhase 3
Local treatment for breast cancer spread to the liver
This study tests a local (targeted) approach for breast cancer that has spread to the liver. It looks at whether treating liver metastases with planned liver surgery, along with standard cancer treatment before and after, can improve outcomes.
UmeåAges 18 years+ - NCT05395962RecruitingPhase 2
Electrotherapy plus two drugs vs drug alone for vulvar cancer
This Phase 2 study compares adding electrotherapy to give carboplatin plus bleomycin directly to the tumor versus giving bleomycin alone. It may help shrink recurrent vulvar cancer when standard options aren’t suitable and your health is limited.
Bologna, BoAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,086 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.