Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07699328RecruitingPhase 1/Phase 2
Study of VRN110755 for EGFR-mutant lung cancer
This trial tests a new oral targeted therapy (VRN110755) for people with EGFR-mutant lung cancer. It is for those whose cancer has advanced or spread, and who either have not been treated yet or who stopped responding to previous EGFR pills.
Bedford Park, South AustraliaAges 18 years+ - NCT06976944RecruitingPhase 2
Pembrolizumab, Paclitaxel, and Bevacizumab for Triple-Negative Breast Cancer
This trial tests a combination of the immunotherapy drug pembrolizumab, the chemotherapy paclitaxel, and possibly the targeted drug bevacizumab for people with triple-negative breast cancer that has returned after treatment. It aims to see if adding bevacizumab improves outcomes for patients whose tumors are PD-L1 positive.
Nagoya, Aichi-kenAges 18 years+ - NCT07699705Recruiting
Proton Beam Therapy for Localized Prostate Cancer
This study tests a very short course (ultrahypofractionated) of proton beam radiation for localized prostate cancer. It aims to see if it's safe and effective with fewer treatment visits.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06703476RecruitingPhase 3
Surgery techniques study for bladder cancer
This trial compares two different surgical approaches during bladder removal surgery: using a stent or not, and using a drug called alvimopan or not. Alvimopan helps the bowels work normally after surgery.
Basking Ridge, New JerseyAges 21 years+ - NCT06732388RecruitingPhase 2
Itraconazole with ablation to prevent esophageal cancer in Barrett's esophagus
This trial tests if adding the antifungal drug itraconazole to standard ablation therapy can help prevent esophageal cancer in people with high-risk Barrett's esophagus. You must have a confirmed diagnosis of Barrett's esophagus with low- or high-grade dysplasia or early-stage cancer, and be planning to have ablation treatment.
Kansas City, KansasAges 18 years+ - NCT06792695RecruitingPhase 2
Study of new treatments for colorectal cancer
This trial tests new treatment combinations for colorectal cancer that has spread (metastatic). It is for people whose cancer is mismatch repair proficient (pMMR) or microsatellite stable (MSS) and who have not had previous treatment for metastatic disease.
Scottsdale, ArizonaAges 18–130 - NCT07672236RecruitingPhase 3
Comparing two mouth pain treatments for head and neck cancer patients
This trial tests a new mouthwash (BupiZenge) against a standard numbing medicine (lidocaine) for pain caused by mouth sores from radiation therapy. It may help you if you are about to start radiation for certain head and neck cancers.
CopenhagenAges 18–80 - NCT07091968Recruiting
Text-message support for depression in cancer survivors
This study is testing a text-message program to help cancer survivors who feel depressed get connected to mental health support. The goal is to see if this simple, phone-based approach makes it easier to follow up on a referral for depression care.
Charleston, South CarolinaAges 18 years+ - NCT06517719Recruiting
Real-world study of Pluvicto for advanced prostate cancer
This study looks at how men with advanced prostate cancer (mCRPC) do when they receive a treatment called Pluvicto (lutetium vipivotide tetraxetan) in real-world settings. It aims to collect information on treatment effectiveness and quality of life without adding any extra procedures or medications.
Konstanz, Baden-WurttembergAges 18–99 - NCT07697170Enrolling by invitation
How often to care for PICC lines in colon or pancreas cancer
This study looks at how often to replace the dressing on a PICC line (a small tube used for chemotherapy) in colon or pancreatic cancer patients to prevent skin damage. If you need a PICC line and receive one of certain chemotherapy regimens, this trial may help find the best care approach.
Badalona, BarcelonaAges 18 years+ - NCT07624617Recruiting
Fasting and Breast Cancer Treatment Study
This study looks at whether periods of fasting (eating for shorter time windows) might help improve how well a breast cancer medication called capivasertib works. You'll wear a glucose monitor, track your food, and follow fasting schedules while continuing your regular cancer treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT07238894Recruiting
Freezing and heating breast cancer without surgery
This study tests a combination of freezing and heating (cryoablation and thermal ablation) to treat breast cancer in patients who cannot have surgery. It may help shrink or control tumors while avoiding general anesthesia.
BeijingAges 18–80 - NCT04934982Recruiting
Surgery trial for early-stage cervical cancer with lymph vessel invasion
This trial studies whether a specific type of surgery (done through the abdomen or with keyhole surgery) is the right treatment for certain early cervical cancers. It aims to see how well these surgeries work when cancer hasn’t spread to lymph nodes.
ShanghaiAges 21–70 - NCT04935853Recruiting
Study of markers that predict bile duct cancer treatment response
This study looks at lab markers (including genetic tests) to predict how people with bile duct cancer respond to treatment. Your answers and samples may help doctors personalize care for bile duct cancer in the future.
AmiensAges 18 years+ - NCT04936581Recruiting
Quality of life after rectal cancer surgery
This study looks at patient-reported outcomes—how you feel and function—after surgery for rectal cancer. It may help doctors better understand recovery and well-being after different surgical approaches and treatments.
MadridAges 18–100 - NCT04938804Recruiting
One-time lung cancer screening with a low-dose chest CT
This study tests whether a one-time, low-dose chest CT scan can help find lung cancer early in certain people. You may be invited because of your age and location, and because you have not had recent related testing or symptoms.
Guangzhou, GuangdongAges 40–74 - NCT04939831Recruiting
Surgery study for certain stages of cervical cancer
This trial looks at two surgical approaches to remove the cervix in people with specific early-to-mid stage cervical cancer. It aims to see which approach is safer and/or works better for cancer control based on your cancer stage and scan results.
Shanghai, Shanghai MunicipalityAges 21–70 - NCT04943484Recruiting
ICG camera dye test during surgery for advanced stomach cancer
This trial tests whether an “ICG” dye and special camera can help surgeons see cancer more clearly during surgery for advanced stomach cancer. It may help improve how safely and accurately surgeons remove the tumor and nearby lymph nodes.
Milan, ItaliaAges 18 years+ - NCT04947059RecruitingPhase 3
Stop bladder cancer coming back with medicine after bladder surgery
This trial tests whether putting chemotherapy medicine directly into the bladder right after surgery helps prevent bladder cancer from coming back. It compares gemcitabine versus epirubicin given as an immediate bladder “wash-in.”
Larissa, Larissa/ThessalyAges 18–100 - NCT04947189RecruitingPhase 1/Phase 2
Seviteronel plus chemo for advanced triple-negative breast cancer
This trial tests seviteronel together with standard chemotherapy to treat certain types of advanced breast cancer that has spread. It’s looking to see how well the combination works and how safe it is, especially for cancers that are androgen-receptor positive.
Darlinghurst, New South WalesAges 18 years+ - NCT04947280RecruitingPhase 1/Phase 2
Radiation split into small doses for breast cancer bone spread
This trial studies a type of focused radiation given in smaller parts to treat bone metastases from breast cancer. It may help shrink tumors and improve control of pain or growth when standard treatments haven’t worked or surgery isn’t possible.
Shanghai, Shanghai MunicipalityAges Any age - NCT04951635RecruitingPhase 3
Almonertinib after chemoradiation for stage III lung cancer
This Phase 3 trial tests whether almonertinib given after standard chemoradiation can help people with stage III, non-surgical lung cancer live longer and/or control the cancer. It is for tumors with specific EGFR mutations linked to sensitivity to EGFR-targeted medicines.
Ji'nan, ShandongAges 18 years+ - NCT04951947RecruitingPhase 2
Study drug plus lenvatinib for advanced small-cell lung cancer
This Phase 2 trial tests JS-201 combined with lenvatinib in people with extensive-stage small-cell lung cancer whose first-line treatment didn’t work. It may help by trying a new combination approach after prior therapy failure.
Changsha, HunanAges 18–75 - NCT04957511Recruiting
Testing gut bacteria in gynecologic cancer patients on immunotherapy
This study looks at how gut bacteria may relate to how well immunotherapy works in people with advanced or returning gynecologic cancer. You may be asked to give stool samples several times so researchers can measure changes in your gut microbiome.
Orlando, FloridaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.