Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,324 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06015880RecruitingPhase 1
Combination drug therapy for relapsed or resistant large B-cell lymphoma
This trial tests a combination of three drugs (mosunetuzumab, polatuzumab vedotin, and lenalidomide) for people with diffuse large B-cell lymphoma (a type of blood cancer) that has come back or not responded to previous treatment. The goal is to see if this combination is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT06016387RecruitingPhase 2
Drug combo with radiation for HER2+ breast cancer spread to spinal lining
This trial tests a combination of three targeted drugs (tucatinib, trastuzumab, and capecitabine) along with radiation to the brain or spine for people whose HER2-positive breast cancer has spread to the lining of the brain or spinal cord. The goal is to see if this treatment is safe and effective.
Ottawa, OntarioAges 18 years+ - NCT06017284RecruitingPhase 3
Thalidomide for nausea in pancreatic cancer patients
This trial tests whether adding thalidomide to standard chemotherapy can help reduce nausea and vomiting in people with advanced pancreatic cancer. It is for patients who have not yet received any cancer treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06018714RecruitingPhase 2
Modified fruquintinib for colorectal cancer with liver metastases
This trial tests a modified version of the drug fruquintinib for people with colorectal cancer that has spread to the liver. It is for those who have had successful liver-directed treatment (surgery, ablation, or radiation) and have no signs of cancer left, then finished chemotherapy without the cancer growing back.
Guangzhou, GuangdongAges 18–75 - NCT06019130RecruitingPhase 2
Nivolumab for newly diagnosed nasopharyngeal cancer
This trial tests whether the immunotherapy drug nivolumab (Opdivo) can help treat nasopharyngeal cancer in both children and adults. It is for people who have just been diagnosed and have not yet received any cancer treatment.
AachenAges 3 years+ - NCT06019923Recruiting
Metabolic biomarkers study in newly diagnosed ovarian cancer
This study looks at certain substances in the body (called metabolic biomarkers) and how they relate to how well patients do after treatment. It is for women who have just been diagnosed with high-grade serous ovarian cancer and have not yet had any treatment.
Hangzhou, ZhejiangAges 18–75 - NCT06020430Recruiting
Skipping routine radiation for advanced lung cancer after immunotherapy and chemo
This trial tests whether it is safe to skip routine radiation to the tumor bed in patients with stage III lung cancer that has responded well to immunotherapy and chemotherapy. It aims to reduce side effects while still controlling the cancer.
Wuhan, HubeiAges 18–75 - NCT06024837Recruiting
Testing spectral CT for colorectal cancer spread to liver or belly
This study tests a new type of CT scan (spectral CT) to see how well it detects colorectal cancer that has spread to the liver or belly lining. It may help doctors better plan surgery to remove all the cancer.
Saint-EtienneAges Any age - NCT06027242Recruiting
Glutamine supplement after stomach cancer surgery
This trial tests if taking glutamine (a nutrient) as an oral supplement helps patients recover after surgery to remove stomach cancer. It aims to see if it improves healing and quality of life.
TaipeiAges 20 years+ - NCT06027892Recruiting
Comparing two shorter radiation treatments for prostate cancer
This trial tests if a two-session radiation treatment works as well as a five-session one for men with low-risk or favorable intermediate-risk prostate cancer. It aims to reduce the number of visits while maintaining effectiveness.
Petah Tikva, IsraelAges 18 years+ - NCT06029036RecruitingPhase 2
Darolutamide and ADT before prostate surgery
This trial tests a combination of darolutamide (a hormone-blocking pill) and standard hormone therapy (ADT) given before prostate surgery. It is for men with high-risk prostate cancer that has not spread to distant parts of the body, to see if the treatment can improve outcomes.
BeijingAges 18–75 - NCT06029504Recruiting
Optical-guided sentinel node biopsy for vulvar cancer staging
This trial tests a new optical method using a dye to find and remove the first lymph node (sentinel node) that cancer might spread to, to stage vulvar cancer more accurately. It's for patients with a smaller tumor (under 4 cm) that hasn't been treated in the groin area before.
CopenhagenAges 18 years+ - NCT06029270RecruitingPhase 2
Adding relatlimab to standard immunotherapy for nasopharyngeal cancer
This trial tests whether adding a new drug called relatlimab to the usual immunotherapy (nivolumab) helps people with nasopharyngeal cancer that has returned or spread. You will get standard chemotherapy plus nivolumab first, then if it works, you may be randomly assigned to get nivolumab alone or with relatlimab.
Dublin, CaliforniaAges 18 years+ - NCT06030011Recruiting
Using a digital tool for head and neck cancer patients
This trial uses a digital assessment tool to track symptoms and side effects in patients with head and neck cancer who are getting radiation therapy (with or without chemotherapy). The goal is to see if it helps improve care in both rural and urban areas.
Kansas City, KansasAges 18 years+ - NCT06033287Recruiting
Real-world study of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well CDK4/6 inhibitors combined with hormone therapy work in real-world settings for people with a certain type of advanced breast cancer (HR+/HER2-). It aims to understand the best treatment path and what happens next.
Changsha, HunanAges 18 years+ - NCT06035250Recruiting
AI predicts stomach cancer response to chemo before surgery
This study tests whether an AI tool can predict how well stomach cancer responds to chemotherapy before surgery. It uses CT scans and biopsy images taken before treatment starts to see if the AI can help guide future care.
BeijingAges 18 years+ - NCT06036745RecruitingPhase 2
Palizumab and SOX chemo after gastric cancer surgery
This trial tests adding palizumab (an immunotherapy) to standard SOX chemotherapy after surgery for stage IIIB-IIIC gastric or GEJ cancer. It's for people whose tumors have certain markers (MSI-H, TMB-H, or high PD-L1) that may make immunotherapy more effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06037681Recruiting
Study on cannabis use and pain outcomes in Black and white patients with cancer
This study looks at how cannabis affects pain and daily life in Black and white patients with solid tumors. It compares people who use cannabis at least once a week to those who don't use it at all.
Buffalo, New YorkAges 21–99 - NCT06037980RecruitingPhase 2/Phase 3
Chemotherapy before surgery for high-risk bile duct cancer
This trial tests whether receiving chemotherapy (cisplatin, gemcitabine, and nab-paclitaxel) before surgery can improve outcomes for people with high-risk bile duct or gallbladder cancer. It compares this approach to going straight to surgery.
AnconaAges 18–75 - NCT06037902Recruiting
CPAP during radiation for esophageal cancer
This study tests whether using a CPAP mask (which gently pushes air into your airways) during radiation therapy makes treatment safer and more effective for esophageal cancer. It is for adults who are planning radiation and can tolerate wearing the mask.
Ramat GanAges 18 years+ - NCT06038032Recruiting
Healthy lifestyle after endometrial cancer
This trial tests a program to help endometrial cancer survivors improve their diet, physical activity, and weight. It aims to see if these changes can reduce the risk of the cancer coming back and improve overall health.
Edmonton, AlbertaAges 18 years+ - NCT06038227Recruiting
Robotic vs. VATS surgery for early lung cancer
This study compares two types of minimally invasive surgery—robotic-assisted (da Vinci) and VATS—for people with early-stage non-small cell lung cancer. The goal is to see which approach might work better and help patients recover faster.
CopenhagenAges 18 years+ - NCT06038318Recruiting
Building resilience for teens and young adults after cancer treatment
This study tests a program called PRISM to help adolescents and young adults feel stronger and cope better after finishing cancer treatment. The program includes talking sessions and surveys to see if it supports resilience.
Boston, MassachusettsAges 12–25 - NCT06038578RecruitingPhase 2
TRK-950 with standard chemo for advanced stomach cancer
This trial tests a new drug, TRK-950, added to standard chemotherapy (ramucirumab and paclitaxel) for people with advanced stomach or gastroesophageal junction cancer that has worsened after previous treatment. The goal is to see if this combination can help shrink tumors or slow disease progression.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,324 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.