Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,117 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06568562RecruitingPhase 2
XL092 for advanced prostate cancer after PSMA therapy
This trial tests a new oral drug, XL092, for men with metastatic castration-resistant prostate cancer that has progressed after PSMA-targeted radiation therapy (Lu-177 PSMA-617). It aims to see if the drug can slow down the cancer.
Salt Lake City, UtahAges 18 years+ - NCT06572735Recruiting
PARP Inhibitor Dosing in Older Ovarian Cancer Patients
This trial studies how well older adults (70+) with advanced ovarian cancer tolerate PARP inhibitors in real-world care. It aims to see if the standard dose works for this age group.
AmiensAges 70 years+ - NCT06574880RecruitingPhase 1/Phase 2
Radiation and Lutetium PSMA for locally advanced prostate cancer
This study tests a combination of focused radiation (SBRT) and a targeted radioactive drug (Lutetium PSMA) for men with prostate cancer that has spread to nearby lymph nodes or has high-risk features but has not yet reached distant organs. The goal is to see if this approach is safe and effective.
Cleveland, OhioAges 18 years+ - NCT05130606Recruiting
Story-based program to improve genetic cancer counseling for Latina women
This study tests a Spanish/English narrative (story-based) program designed to help improve genetic counseling and genetic testing for hereditary breast and ovarian cancer risk. It may help you better understand your options and feel more prepared to get the right type of genetic care.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05576480RecruitingPhase 2
Immunotherapy plus chemotherapy before surgery for rectal cancer without mismatch repair
This Phase 2 study tests penpulimab (an immunotherapy medicine) given with CAPEOX chemotherapy before surgery for rectal cancer that is “MSS” (not the mismatch-repair type). It aims to shrink the tumor and improve outcomes by treating before the operation.
Shanghai, None SelectedAges 18–75 - NCT06331013Recruiting
CyberKnife Radiation for Prostate Cancer
This trial tests a high-precision radiation treatment (CyberKnife SBRT) for prostate cancer that is still within the prostate. It aims to see if a very short course of radiation works well with fewer side effects.
MilanAges 18–80 - NCT06490536RecruitingPhase 3
Testing a new treatment for high-risk colon cancer after surgery
This trial tests a new treatment approach for people with certain high-risk colon cancers (stage II or III in the upper colon) after surgery. It aims to see if adding a study drug can help prevent the cancer from coming back.
BerlinAges 18 years+ - NCT06564324RecruitingPhase 3
Comparing taletrectinib to standard therapy for ROS1-positive lung cancer
This study compares a new targeted therapy pill (taletrectinib) to standard treatments for people with advanced ROS1-positive lung cancer. The goal is to see if taletrectinib works better at shrinking tumors and delaying cancer growth.
Hefei, AnhuiAges 18 years+ - NCT06549465RecruitingPhase 2
Ac-225 rosopatamab for PSMA-positive castration-resistant prostate cancer
This trial tests a radioactive drug (Ac-225 rosopatamab tetraxetan) that targets a protein called PSMA on prostate cancer cells. It is for patients whose cancer has stopped responding to hormone therapy and has spread to other parts of the body.
San Diego, CaliforniaAges 18 years+ - NCT06562543RecruitingPhase 4
Fruquintinib for advanced colorectal cancer in minority populations
This trial tests a medication called fruquintinib (an oral pill) for people with advanced colorectal cancer that has not responded to prior treatments. It is specifically looking for participants who identify as Black or African American and/or Hispanic or Latino to help understand how the drug works in these groups.
Birmingham, AlabamaAges 18 years+ - NCT06549725Recruiting
Lipidica software for pancreatic cancer screening
This trial tests a software that analyzes fats (lipids) in your blood to find pancreatic cancer early. You may join if you have pancreatic cancer that can be removed with surgery, or if you are at very high risk due to family history or certain gene mutations.
Prague, CzechiaAges 18 years+ - NCT06562647Recruiting
Testing SY001 for advanced ovarian or pancreatic cancer with mesothelin
This trial tests a new drug called SY001, which targets a protein called mesothelin found on some cancer cells. It is designed for people with advanced ovarian or pancreatic cancer who have already tried other treatments and whose tumor tissue has mesothelin.
Hangzhou, ZhejiangAges 18–75 - NCT06559371Recruiting
PET scan to check lymph nodes after breast cancer treatment
This study uses a special PET scan (68Ga FAPI) to check if lymph nodes under the arm still have cancer after you finish pre-surgery treatment. It helps doctors see how well the treatment worked before you have surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06563479RecruitingPhase 3
Personalized vs. standard radiation for HPV-positive throat cancer
This trial compares a personalized, shorter course of radiation therapy to the standard longer course for people with HPV-positive throat cancer. The goal is to see if personalized treatment is just as effective while reducing side effects.
Hartford, ConnecticutAges 18 years+ - NCT06549855Recruiting
PD-1 inhibitor plus progesterone for fertility preservation in MMRd endometrial cancer
This trial tests a combination of an immunotherapy drug (PD-1 inhibitor) and progesterone hormone therapy to treat early-stage, MMR-deficient endometrial cancer while preserving fertility. It may help young women who want to keep the option to have children in the future.
Beijing, Beijing MunicipalityAges 18–45 - NCT06559540RecruitingPhase 2
Compare short radiation courses for node-positive breast cancer
This study compares two shorter courses of radiation therapy for women with node-positive breast cancer. It aims to see if an ultra-short course is as safe and effective as the slightly longer short course.
St Louis, MissouriAges 18 years+ - NCT06551220Recruiting
T-DXd for advanced breast cancer with various HER2 levels
This study looks at how well the drug T-DXd (Enhertu) works against breast cancer that has spread or can't be removed with surgery. It includes patients with any level of HER2 protein, so it might be an option even if your cancer has low HER2.
New Haven, ConnecticutAges 18–80 - NCT06552598RecruitingPhase 1
KD01 for advanced gynecologic cancers
This trial tests a new drug called KD01 for women with advanced gynecologic cancers (like cervical or endometrial cancer) that haven't responded to other treatments. It also has a separate part for younger women who want to preserve their fertility.
Wuhan, HubeiAges 18 years+ - NCT06561308RecruitingPhase 2
Immunotherapy plus chemo for advanced endometrial cancer
This trial tests a combination of a PD-1 inhibitor (a type of immunotherapy) with chemotherapy given before surgery for advanced endometrial cancer. The goal is to see if this approach helps shrink the tumor and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT06560398Recruiting
Better outreach to connect people with cancer trials
This study tests new ways to connect people in Florida communities with cancer care and research opportunities. It focuses on making it easier for patients, doctors, and community members to learn about and join clinical trials.
Tampa, FloridaAges 18 years+ - NCT06562166RecruitingPhase 2
Online adaptive radiotherapy for cervical cancer
This trial tests a type of radiation that adapts to your body changes during treatment for cervical cancer. It aims to improve accuracy and reduce side effects.
BeijingAges 18–80 - NCT06562777Recruiting
How symptoms differ between men and women during immunotherapy
This study looks at how symptoms during immunotherapy (a cancer treatment that boosts your immune system) may differ between men and women. Researchers will follow people with cancer who are starting immunotherapy to see if men and women report different side effects.
Portland, OregonAges 18 years+ - NCT06554158Recruiting
Lowering radiation for low-risk HPV throat cancer patients
This trial tests whether giving less radiation after surgery is safe and effective for people with early-stage HPV-related throat cancer. It aims to reduce side effects while still controlling the cancer.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06553885RecruitingPhase 2
Study of enfortumab vedotin for advanced colorectal or liver cancer
This trial tests a drug called enfortumab vedotin for people whose colorectal or liver cancer has spread or cannot be removed and has stopped responding to or is intolerant to standard treatments. The drug is given through a vein and works by targeting cancer cells.
Tampa, FloridaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,117 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.