Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,086 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05843877RecruitingPhase 3
Surgery choice and insulin islet transplant to prevent leaks
This Phase 3 trial studies a pancreatic surgery approach (pylorus-preserving Whipple or similar) and, in some cases, moving your insulin-making cells into your body to help prevent a dangerous post-surgery leak from the pancreas. It may help people who are considered high risk for this complication based on pancreas texture and duct size.
DresdenAges 18 years+ - NCT05845450RecruitingPhase 2
Pre-surgery targeted drugs for selected colorectal cancer tumors
This trial tests targeted cancer drugs given before planned colon or rectal surgery. It may help by trying to shrink the tumor and treat specific tumor “targets” found in your stored pathology sample, depending on your tumor’s genetics and marker tests.
Milan, Lombardia/MIAges 18 years+ - NCT05831397Recruiting
Study tests tiny blood “packages” during breast cancer chemotherapy
This trial studies small particles in the blood (called extracellular vesicles) in people receiving chemotherapy before surgery for breast cancer. It may help doctors learn more about what those particles can tell them during neoadjuvant treatment.
Pavia, LombardyAges 18–80 - NCT05831878Recruiting
Drug RC48 for HER2-low or HER2-ultralow breast cancer
This trial tests RC48, an antibody-drug treatment, for people with advanced breast cancer that cannot be cured or removed, specifically HER2-low (or HER2-ultralow) tumors. It may help by targeting cancer cells with this “HER2-low” trait while limiting spread in the body.
ShanghaiAges 18 years+ - NCT05837039Recruiting
Comparing caregiver and nurse views of discomfort in advanced cancer
This study compares how healthcare providers and family caregivers judge discomfort in people with advanced cancer who are very hard to rouse and may be actively dying. It aims to understand whether caregiver and staff perceptions match, which could improve comfort care for patients near the end of life.
Houston, TexasAges 18 years+ - NCT05842902Recruiting
Mobile app program to build resilience for young cancer patients
This trial tests a phone-based (mobile) resilience program for teens and young adults who were recently diagnosed with cancer. It aims to help you cope with cancer using interactive activities, interviews, and short surveys.
Seattle, WashingtonAges 12–25 - NCT05832086RecruitingPhase 2
Fasting-mimicking diet to improve prostate cancer and metabolism
This trial tests whether an intermittent, fasting-like diet can help control metastatic prostate cancer and improve metabolic health in men on hormone therapy. Participants follow a specific diet plan and are monitored by the study team.
Duarte, CaliforniaAges Any age - NCT05838521RecruitingPhase 2
IMMU-132 for cervical cancer that returned or did not go away
This trial studies IMMU-132 (sacituzumab govitecan) in people whose cervical cancer keeps coming back or stays after prior treatment. It aims to shrink tumors and improve outcomes after at least one chemotherapy has already been tried.
New Haven, ConnecticutAges 18 years+ - NCT05829070Recruiting
Helps young adult cancer survivors understand health insurance
This study tests a program to improve health insurance know-how for young people who have finished cancer treatment. It may help you navigate coverage, costs, and benefits more confidently after cancer.
Murray, UtahAges 26–45 - NCT05825950Recruiting
AI tool for predicting outcomes in bladder cancer
This trial tests an artificial-intelligence (AI) tool that uses your bladder cancer details to help predict outcomes. It may help doctors better choose the next treatment after bladder cancer is found early (non-muscle invasive).
Dallas, TexasAges 18–99 - NCT05812287Recruiting
Testing differences between two types of stomach cancer using lab data
This study compares two kinds of stomach cancer (near the upper stomach/“cardia” vs non-cardia) using special lab and genetic tests (“multiomics”). It may help doctors understand differences between these cancers and improve how they are diagnosed and treated.
Jinan, ShandongAges 18–75 - NCT05568212RecruitingPhase 2
Trial of immune combination versus standard care for NSCLC relapse
This Phase 2 trial studies an immune-based drug combination compared with standard care for lung cancer that has come back after chemoradiation and durvalumab. It aims to improve control of the cancer after durvalumab is no longer working.
Roma, RMAges 18 years+ - NCT05805631RecruitingPhase 2
Pemetrexed into spinal fluid for EGFR-mutant lung cancer spread to brain lining
This Phase 2 trial tests giving pemetrexed directly into the spinal fluid to treat cancer that has spread to the brain’s and spinal cord’s lining (leptomeningeal metastasis). It is for people with EGFR-mutant non-squamous lung cancer whose disease progressed after osimertinib, and who may benefit from a targeted treatment delivered to the area affected in the brain lining.
Taipei, TaiwanAges 20 years+ - NCT04063501Recruiting
Study of gut microbes during immunotherapy for lung cancer
This trial studies how gut bacteria (the microbiome) and the body’s immune signs change over time while you receive PD-1–based immunotherapy for advanced, unresectable non–small cell lung cancer. The goal is to learn which immune and microbial patterns might relate to how well treatment works and how patients respond.
New York, New YorkAges 18–100 - NCT05805371RecruitingPhase 1
PSCA CAR-T cells with or without radiation for prostate cancer
This Phase 1 study tests a prostate cancer treatment made of PSCA-targeted CAR-T cells, with or without radiation, to help control advanced prostate cancer. It aims to find a safe treatment approach and see how well it works in people whose cancer has PSCA.
Duarte, CaliforniaAges 18 years+ - NCT05788744Recruiting
Testing DNA-based blood tests in early pancreatic cancer
This study looks at DNA signals from blood tests (so-called “ctDNA” and another type of DNA test) in people with early-stage pancreatic cancer. It aims to see whether these tests can help track cancer after surgery and check for signs of return.
AalborgAges Any age - NCT05805722Recruiting
Tobacco quit program for cancer patients and recent quitters
This study offers a structured tobacco-cessation program for people with a history of cancer who currently use tobacco or quit recently. It tests approaches to help you stop using tobacco and stay quit while you’re getting care or recovering.
Richmond, VirginiaAges 18 years+ - NCT05811936Recruiting
SNAP support tool for head and neck cancer survivors and caregivers
This trial tests a “SNAP” support tool designed for people who have head and neck cancer and the caregiver who helps them. It aims to improve support and coping during and after cancer treatment by involving both the survivor and their main support person.
Charleston, South CarolinaAges 18 years+ - NCT05780814Recruiting
Treating insomnia to improve weight loss after breast cancer
This study looks at whether improving insomnia (trouble falling asleep or staying asleep) can help survivors of breast cancer lose weight more successfully through a structured behavioral weight loss program. It may help if sleep problems are making it harder to change eating and activity habits.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05790213RecruitingPhase 2
Hormone therapy plus targeted prostate treatment for intermediate cancer
This Phase 2 study tests whether combining hormone treatment (androgen deprivation therapy) with focal ablation (targeted destruction of prostate tissue) controls intermediate-risk prostate cancer. It may help some men avoid or reduce more aggressive treatment, while still aiming for cancer control.
Chicago, IllinoisAges 18 years+ - NCT05786716RecruitingPhase 2/Phase 3
Trastuzumab plus pertuzumab for HER2-mutated cancers
This trial tests whether combining trastuzumab and pertuzumab can treat cancers that have HER2 amplification or an activating HER2 mutation. It looks at people ages 12 and older, and may include both children/teens and adults, using the study drug based on their HER2 test results.
BelfastAges 12 years+ - NCT05806060RecruitingPhase 3
Targeted first treatment for a rare TNBC subtype with spread
This Phase 3 trial tests a more precise treatment strategy for a specific rare type of triple-negative breast cancer (TNBC) called the BLIS subtype. It’s for people whose cancer has spread or cannot be fully removed and who have not had chemo or targeted therapy for metastatic TNBC yet.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05810467Recruiting
Active surveillance study for men at higher risk prostate cancer
This trial studies how well “active surveillance” works for men with prostate cancer who are considered higher risk because of family history or genetics. It aims to safely monitor the cancer and decide the best timing for treatment if needed, while tracking side effects and follow-up success.
Sutton, SurreyAges 18 years+ - NCT05798338Recruiting
Study blood samples and tiny cell particles in breast cancer
This study looks at tiny particles released by cells (called extracellular vesicles) in people with breast cancer. It may help researchers better understand breast cancer and how it behaves, which could improve future testing or treatments.
Pavia, LombardyAges 18–90
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,086 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.