Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04518501RecruitingPhase 1/Phase 2
Testing fuzuloparib with arsenic and platinum for ovarian cancer
This early-phase study tests a combination of three medicines to treat ovarian, fallopian tube, or primary peritoneal cancer that has come back after platinum chemotherapy, especially when tumors have a BRCA1 or BRCA2 mutation. The goal is to see if this treatment can help control cancer that is hard to treat.
Zhejiang, HangzhouAges 18–70 - NCT07478289RecruitingPhase 2
Radiation boost for painful spinal metastases
This trial tests a higher dose of radiation (a boost) to painful spots in the spine where cancer has spread. The goal is to see if it can better relieve pain and improve function.
Toronto, OntarioAges 18 years+ - NCT06463262Recruiting
Personalized markers for chordoma before surgery and radiation
This trial tests whether analyzing blood and tumor samples before and after radiation and surgery can help find personalized markers for chordoma. It is for patients with chordoma of the skull base, spine, or sacrum who will receive radiation before surgery.
Baltimore, MarylandAges 18 years+ - NCT06959108RecruitingPhase 2
Comparing two treatments for head and neck cancer before chemoradiation
This trial tests two different drug combos—one using an EGFR-targeted therapy alone, the other adding an immunotherapy—before standard chemoradiation for locally advanced head and neck cancer. The goal is to see which approach works better without prior treatment.
VillejuifAges 18–75 - NCT06668584RecruitingPhase 2
Olutasidenib to prevent cancer return after stem cell transplant
This study tests if a daily pill called olutasidenib can help keep your cancer from coming back after a stem cell transplant. It's for people with a specific IDH1 gene change and myeloid cancers like AML or MDS.
Houston, TexasAges 18–75 - NCT06644716Recruiting
FAPI PET-CT scan to find unknown primary cancer
This study tests a new type of PET-CT scan using a tracer called FAPI to find the original source of cancer when standard tests have not been able to. It may help identify the primary tumor in people with cancer that has spread from an unknown location.
AmsterdamAges 18–99 - NCT07456904Recruiting
Transition to adult care for cancer risk patients
This study looks at how young adults with a genetic risk for cancer (cancer predisposition syndrome) transition from St. Jude children's care to adult healthcare. It aims to understand their health outcomes and help improve future care.
Memphis, TennesseeAges 18 years+ - NCT05257993RecruitingPhase 1/Phase 2
Pancreatic cancer trial testing JPI-547 with standard chemo
This study tests whether adding JPI-547 to standard chemotherapy (modified FOLFIRINOX or gemcitabine with nab-paclitaxel) is safe and tolerable in people with advanced pancreatic cancer. If it works, it may improve treatment options for cancers that have spread or cannot be removed with surgery.
Gyeonggi-doAges 19–79 - NCT06454955RecruitingEarly Phase 1
PET scan imaging study for solid tumors using a new probe
This trial tests a new imaging agent that targets a protein called B7-H3 found on many solid tumors. It uses PET/CT to help doctors see and stage tumors more clearly.
Beijing, Beijing MunicipalityAges 18–75 - NCT07691619RecruitingPhase 2
Shorter radiation after surgery for thymus cancer
This trial tests a shorter course of radiation therapy (hypofractionated) after surgery for people with Stage II or III thymoma or thymic cancer. The goal is to prevent the tumor from coming back.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06612645RecruitingPhase 1
CAR T cell therapy for children with solid tumors that returned
This trial tests a new type of immune therapy called CAR T cells designed to find and attack a protein called B7-H3 on solid tumor cells. It's for children and young adults whose cancer came back or didn't respond to standard treatment.
Bangkok, PathumwanAges 1–25 - NCT07453342Recruiting
Safety of immunotherapy side effects and restarting treatment
This study looks at patients who had side effects from cancer immunotherapy (checkpoint inhibitors). The goal is to understand those side effects and whether it is safe to restart immunotherapy after they resolve.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07449208Recruiting
Esophagectomy leak risk registry study
This study follows people having surgery to remove part of the esophagus (esophagectomy) who are at higher risk for a leak where the esophagus is reconnected. The goal is to learn more about who develops leaks and how to prevent them.
Basking Ridge, New JerseyAges 18 years+ - NCT07443397RecruitingPhase 3
Anlotinib plus whole-brain radiation for SCLC brain metastases
This trial tests whether combining Anlotinib (a targeted drug that blocks tumor blood vessel growth) with whole-brain radiation can better control brain metastases in small cell lung cancer patients. It is for people with up to 10 brain tumors who have not had brain radiation before.
Beijing, Beijing MunicipalityAges 18–80 - NCT07428278Recruiting
Resilience-building for advance care planning in cancer
This trial tests a program to help people with advanced cancer and their family caregivers build resilience while planning future medical care. It aims to improve communication and preparedness.
Chicago, IllinoisAges 18–80 - NCT06447727Recruiting
Y-90 beads plus chemo for liver-only colorectal cancer
This trial tests whether adding radioactive Y-90 microspheres (tiny beads that deliver radiation directly to liver tumors) to standard chemo (FOLFIRI and bevacizumab) can help people with advanced colorectal cancer that has spread only to one lobe of the liver, when the first treatment stopped working. The goal is to slow down tumor growth.
Nanjing, JiangsuAges 18–75 - NCT05209620RecruitingPhase 2
Orelabrutinib plus pemetrexed for lymphoma in the brain
This Phase 2 trial tests a combination medicine (orelabrutinib with pemetrexed) to treat lymphoma that has returned or is not responding, specifically in the brain or spinal fluid. If you qualify, the goal is to shrink measurable tumors and improve control of central nervous system lymphoma.
Zhengzhou, HenanAges 18–75 - NCT07093866RecruitingPhase 2
Targeted drug combo for advanced prostate cancer
This trial tests a combination of two drugs—disitamab vedotin (a targeted antibody-drug that attacks HER2-positive cancer cells) and abiraterone (a hormone therapy)—to see if they can slow or shrink prostate cancer that has spread and become resistant to standard treatments.
Nanjing, JiangsuAges 18–75 - NCT05197881Recruiting
Daily adaptive radiation for newly diagnosed cervical cancer
This study tests a radiation plan that is adjusted day by day to better match your cervix and surrounding tissues during treatment. It’s for newly diagnosed, advanced cervical cancer patients who will receive standard pelvic radiation and chemotherapy.
Burmingham, AlabamaAges 18 years+ - NCT07444268RecruitingPhase 1
Study of how DSP-5336 is processed in the body in advanced blood cancer patients
This trial looks at how your body absorbs, breaks down, and gets rid of the study drug DSP-5336 after a single dose. It is for people with advanced blood cancers that have come back or not responded to other treatments.
Chapel Hill, North CarolinaAges 18 years+ - NCT06636123RecruitingPhase 1
Testing GZ17-6.02 for advanced prostate cancer after hormone therapy
This trial tests a new drug combination (GZ17-6.02) for men with advanced prostate cancer that has stopped responding to standard hormone therapies. The goal is to see if the drug can help slow down the cancer.
Richmond, VirginiaAges 18 years+ - NCT06587490RecruitingPhase 3
Radiation therapy for limited metastatic cancers
This trial tests whether adding focused, high-dose radiation (SABR) to standard drug therapy can better control cancer that has spread to a few spots in the body. It is for people starting or resuming cancer medicines for newly found or growing metastases.
La Jolla, CaliforniaAges 18 years+ - NCT07420101Recruiting
Reducing scan anxiety in caregivers with meditation
This study tests if meditation programs can help ease the anxiety caregivers feel when a loved one with cancer has a routine scan. You will be asked to follow a meditation program and possibly eat a raisin as part of a mindfulness exercise.
Hartford, ConnecticutAges 18 years+ - NCT07416513Recruiting
Digital tools for better cancer care
This study explores how digital tools (apps or websites) can help people affected by cancer, including patients, caregivers, and healthcare workers. If you are a current or past cancer patient, a caregiver, or an oncology professional, you may be able to join.
CaenAges 12 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.