Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,069 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07625423RecruitingPhase 1
Gene therapy injection for advanced head and neck cancer
This trial tests a new treatment where a specially designed virus carrying an anti-cancer gene is injected directly into tumors in the head and neck area. It's for patients whose cancer has come back or spread after prior chemotherapy and who cannot have surgery or radiation.
Chengdu, ChinaAges 18–65 - NCT07622836Recruiting
Chemotherapy plus QL1706 for high-risk triple-negative breast cancer
This study tests whether adding a new immunotherapy drug called QL1706 to standard chemotherapy after surgery can help patients with aggressive triple-negative breast cancer that has spread to lymph nodes. The goal is to see if this combination prevents cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT07623265Recruiting
Understanding Immunotherapy Response in Liver Cancer
This study collects tumor samples and medical information from patients with liver cancer to understand why some patients respond better to immunotherapy (immune-boosting drugs) than others. The goal is to improve treatment selection and outcomes for future patients.
AntwerpAges 18 years+ - NCT07627906RecruitingPhase 3
Comparing Two Sedatives to Prevent Confusion After Cancer Surgery
This study tests two different sedative medications (ketofol and ketodex) to see which one better prevents postoperative delirium—a type of confusion that can happen after surgery—in older adults undergoing cancer surgery. The goal is to find the safest, most effective option for elderly patients.
Cairo, Cairo GovernorateAges 60 years+ - NCT07624513RecruitingPhase 3
Drug combination with planned stem cell transplant for newly diagnosed myeloma
This trial tests a combination of study drugs as the first treatment for newly diagnosed multiple myeloma, followed by maintenance based on your risk and response. It aims to improve outcomes while allowing some patients to postpone or avoid a stem cell transplant.
Boston, MassachusettsAges 18–75 - NCT06697665RecruitingEarly Phase 1
LM103 vaccine with PD-1 for advanced solid tumors
This trial tests a new personalized cancer vaccine (LM103) combined with an immunotherapy drug (PD-1) for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if this combination is safe and can help shrink tumors.
China, Tianjin MunicipalityAges 18–75 - NCT06696742RecruitingPhase 2
PD-1 inhibitor plus probiotic for bladder cancer
This trial tests a combination of a PD-1 inhibitor (which helps your immune system fight cancer) and a probiotic called Clostridium butyricum for people with bladder cancer. It is for those who either have invasive bladder cancer before surgery, or have high-risk features after surgery, and haven't had previous immunotherapy or chemotherapy.
Nanjing, JiangsuAges 18 years+ - NCT05738434RecruitingPhase 2
Testing immunotherapy plus targeted drug with short chemo for esophagus cancer
This Phase 2 study tests whether combining camrelizumab (immunotherapy) and apatinib (a targeted drug) with short-course chemotherapy can control advanced esophageal squamous cell carcinoma. It may help by improving cancer response and slowing disease growth if you’re eligible and haven’t had prior whole-body (systemic) anti-cancer treatment.
Zhengzhou, HenanAges 18–75 - NCT06033183Recruiting
Study of radiation sensitivity in children with cancer
This study looks at how children's bodies respond to radiation therapy for certain cancers. By analyzing blood samples, researchers hope to learn why some children experience more side effects, which could help personalize future treatments.
CaenAges 3–18 - NCT05894369Recruiting
Testing how the tumor environment affects pre-op chemo plus immunotherapy
This study looks at people with esophageal squamous cell carcinoma to see how changes in the “tumor neighborhood” may affect how well treatment works before surgery. If you’re eligible, you would receive chemotherapy plus immunotherapy as neoadjuvant (before-surgery) treatment.
Wuhan, HubeiAges 18–80 - NCT05512286Recruiting
Radiation experience after breast surgery with belly flap
This trial looks at how people feel (patient-reported outcomes) and how safe treatment is when radiotherapy is given after a mastectomy with a DIEP belly skin-flap reconstruction. It may help doctors understand which experiences to expect and how to improve care.
Nanning, GuangxiAges 18 years+ - NCT06702826RecruitingPhase 2
Cadonilimab plus radiation for lung cancer brain mets
This trial tests a combination of a targeted immunotherapy drug (cadonilimab) with a precise type of radiation to treat brain tumors that have grown after initial lung cancer treatment. The goal is to see if this approach can safely shrink brain metastases and improve outcomes.
Changsha, HunanAges 18–75 - NCT06700369Recruiting
Lowering chemo with targeted therapy for HER2+ breast cancer
This study looks at whether using targeted therapy can reduce the amount of chemotherapy needed before surgery for HER2-positive breast cancer. It aims to find a safer, equally effective treatment plan.
Beijing, Beijing MunicipalityAges Any age - NCT07615049RecruitingPhase 3
Shorter versus standard radiation for soft tissue sarcoma
This trial compares a shorter course of radiation therapy with the standard longer course for people with soft tissue sarcoma in an arm or leg. The goal is to see if the shorter course works just as well and may be more convenient.
Birmingham, AlabamaAges 18 years+ - NCT06702566Recruiting
Study of Ferritin in Immune-Related Side Effects
This study looks at how a blood marker called ferritin relates to side effects from immunotherapy or other cancer treatments. It may help doctors predict and manage those side effects better.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06700382Recruiting
Capecitabine for TNBC after incomplete response
This trial looks at different ways to use the chemotherapy drug capecitabine for people with triple-negative breast cancer who still have cancer cells after initial treatment and surgery. It aims to find the best approach to improve outcomes.
Beijing, Beijing MunicipalityAges Any age - NCT06211114RecruitingPhase 2
Immunotherapy and targeted drug for advanced collecting duct kidney cancer
This trial tests a combination of immunotherapy and a targeted drug (axitinib) for people with advanced collecting duct carcinoma, a rare type of kidney cancer. The goal is to see if this treatment can shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18–80 - NCT05967143Recruiting
Registry study for first-time SIR-Spheres in liver tumors
This is an observational (real-world) study that follows people with certain unresectable liver tumors who are getting SIR-Spheres for the first time. It helps doctors understand how this treatment is used in routine care and what outcomes patients experience.
Clichy, CedexAges 18 years+ - NCT06704555RecruitingPhase 2
Radiation plus drug combo for untreated bulky follicular lymphoma
This trial tests a combination of radiation, an immunotherapy drug (tislelizumab), and chemotherapy (RCHOP) for people with previously untreated bulky follicular lymphoma. It aims to see if giving radiation first followed by the drug combo can improve outcomes for larger tumors.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07618624Enrolling by invitationPhase 2
Drug combination before surgery for recurrent head and neck cancer
This trial tests three drugs (finotonlimab, cetuximab, and docetaxel) given before surgery to remove recurrent head and neck cancer in patients whose cancer stopped responding to previous immunotherapy. The goal is to shrink the tumor and improve surgical outcomes.
Foshan, GuangdongAges 18–75 - NCT07616245Recruiting
Special feeding to prevent fluid leaks after esophageal surgery
This study tests whether a special type of nutritional feeding through a tube placed in your small intestine can reduce complications (fluid leaks) after surgery to remove your esophagus for cancer. Researchers hope this approach may help you recover faster and spend less time in the hospital.
Beaumont, DublinAges 18 years+ - NCT07618078Recruiting
Personalized Cancer Risk Assessment for Nasopharyngeal Cancer
This study helps doctors predict which patients with nasopharyngeal cancer (a cancer of the upper throat) will benefit most from additional chemotherapy after radiation treatment. It uses a special blood test and imaging to create a personalized risk score for each patient.
Beijing, Beijing MunicipalityAges 18–75 - NCT07614594Recruiting
Urine Test to Detect Bladder and Kidney Cancer
This study tests whether a simple urine test can accurately identify cancer in the bladder, ureters (tubes between kidneys and bladder), or renal pelvis (part of the kidney). You would provide urine samples before your planned surgery, and researchers will compare the urine test results to your actual tissue diagnosis after surgery.
Zhengzhou, HenanAges 18 years+ - NCT07619417Enrolling by invitation
Electric pulse ablation for pancreatic growths
This trial uses a special endoscopic tool to deliver electric pulses to abnormal growths in the pancreas. It may help people who cannot have surgery for these growths.
Columbus, OhioAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,069 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.