Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,069 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07635641Recruiting
Proton Therapy for Recurring Head and Neck Cancer
This study tracks how well proton therapy (a precise radiation treatment) works when head and neck cancer comes back after previous treatment. Proton therapy uses high-energy particles instead of traditional X-rays, which may reduce side effects.
Rozzano, MilanoAges 18 years+ - NCT07636824RecruitingPhase 2
Chemotherapy plus radiation after bile duct cancer surgery
This study tests whether combining chemotherapy and radiation therapy after surgery improves outcomes for patients with bile duct or gallbladder cancer. It's designed for patients whose surgery showed signs the cancer might come back.
BeijingAges 18–80 - NCT07632339RecruitingPhase 2
New drug combination for recurrent head and neck cancer
This trial tests two drugs—becotatug vedotin and pucotenlimab—given before surgery to treat head and neck cancer that has come back in the same area. The goal is to shrink the tumor and help your body's immune system fight the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07633236RecruitingPhase 3
Olanzapine to prevent appetite and weight loss during cancer chemotherapy
This study tests whether olanzapine, a medication that can increase appetite, helps prevent severe appetite loss and muscle wasting in patients with ovarian or stomach cancer who are receiving chemotherapy before surgery. The goal is to help patients maintain nutrition and strength during treatment.
MoscowAges Any age - NCT07637630Recruiting
HPV Vaccine Education for Vietnamese American Parents
This study helps parents in the Vietnamese American community learn about the HPV vaccine, which prevents certain cancers. Researchers will work with you to understand what information helps families decide about vaccinating their children.
Chicago, IllinoisAges 18 years+ - NCT07633756RecruitingPhase 1
Testing RB1-negative Leiomyosarcoma Treatment with REC-617
This study tests a new drug called REC-617 in patients with a rare muscle cancer (leiomyosarcoma) that has spread or cannot be surgically removed. The drug targets cancer cells that lack a specific protein called RB1, and you must have already tried at least one other cancer treatment before joining.
Houston, TexasAges 18 years+ - NCT07632664Recruiting
New treatment model for older lung cancer surgery patients
This study tests a new approach to help older adults (65+) with early-stage lung cancer who are candidates for surgery. The goal is to improve outcomes by using a special assessment to understand each patient's overall health before and after the operation.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07633626Recruiting
Vortioxetine for thinking problems from ALK lung cancer treatment
This trial tests whether a medication called vortioxetine can help improve memory, focus, and thinking problems caused by lorlatinib, a drug used to treat ALK-positive lung cancer. You would take vortioxetine alongside your current cancer treatment to see if it helps your brain function.
BogotáAges 18 years+ - NCT07635420RecruitingPhase 4
Testing a Dye to Check Blood Flow in Neck Reconstruction Surgery
This study compares a special imaging dye (indocyanine green) that helps surgeons see blood flow in reconstructed tissue during head and neck surgery. The goal is to see if using this dye helps surgeons make better decisions about whether the reconstructed tissue will survive and heal properly.
MalmöAges 18 years+ - NCT06160206RecruitingPhase 2
Study of retifanlimab, bevacizumab, and radiation for recurrent glioblastoma
This trial tests a combination of immunotherapy (retifanlimab), a targeted drug (bevacizumab), and low-dose radiation for people whose glioblastoma has come back. The goal is to see if this treatment can help shrink or slow the tumor.
Scottsdale, ArizonaAges 18 years+ - NCT06222957Recruiting
How HER2 affects brown fat in breast cancer patients
This study looks at how a protein called HER2 affects brown fat activity in women with breast cancer. Brown fat helps burn calories and may influence treatment outcomes. You will be assigned to one of two groups based on your cancer's HER2 status, and the study will measure how your brown fat responds to cold.
CopenhagenAges 18 years+ - NCT06252662RecruitingPhase 4
Comparing two numbing medicines for mastectomy nerve blocks
This study compares two types of numbing medicine given through a nerve block before a mastectomy. One is a long-acting version (liposomal bupivacaine) and the other is a standard numbing medicine combined with a sedative (bupivacaine with dexmedetomidine). The goal is to see which provides better pain relief after surgery.
Portsmouth, VirginiaAges 18 years+ - NCT06301399RecruitingPhase 2
Rituximab with prior therapy for advanced liver cancer
This trial tests if adding rituximab to previous cancer treatments can help people with advanced hepatocellular carcinoma (a type of liver cancer) that has stopped responding or caused side effects. It aims to see if this combination is safe and effective.
Tianjin, Tianjin MunicipalityAges 17–79 - NCT06631443Recruiting
Asian Watch-and-Wait Study for Rectal Cancer
This study is for people with rectal cancer who have had treatment like radiation or chemo and their tumor has disappeared or nearly disappeared. Instead of surgery right away, doctors will closely monitor the cancer with regular check-ups to make sure it stays gone.
Mumbai, MaharashtraAges 18 years+ - NCT06610799RecruitingPhase 1
Study of IBI363 for first-line advanced gastric cancer
This trial tests a new drug called IBI363 in patients with advanced gastric or gastroesophageal junction cancer who have not yet received any treatment. The goal is to see if the drug can help shrink tumors or slow the cancer's growth.
Hangzhou, ZhejiangAges 18–75 - NCT07621471RecruitingEarly Phase 1
NK Cell Therapy Enhanced with IL-15 for Advanced Solid Tumors
This early-stage trial tests a new type of immune cell therapy (NK cells boosted with a protein called IL-15) to treat solid cancers that have spread or come back after standard treatment. The goal is to see if this approach can help shrink tumors and improve survival.
ChongqingAges 18–70 - NCT07624318Recruiting
TROP2 Lung Cancer Tissue Study
This research study analyzes lung cancer tissue samples to understand a protein called TROP2 and how it might help guide treatment decisions. You may qualify if you have non-squamous lung cancer and haven't received prior systemic chemotherapy or immunotherapy for advanced disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06692725Recruiting
Lighter chemo with immunotherapy for triple-negative breast cancer
This trial tests whether using less chemotherapy combined with immunotherapy before surgery works well for people with stage II or III triple-negative breast cancer. The goal is to reduce side effects while still being effective.
Beijing, Beijing MunicipalityAges Any age - NCT07627906RecruitingPhase 3
Comparing Two Sedatives to Prevent Confusion After Cancer Surgery
This study tests two different sedative medications (ketofol and ketodex) to see which one better prevents postoperative delirium—a type of confusion that can happen after surgery—in older adults undergoing cancer surgery. The goal is to find the safest, most effective option for elderly patients.
Cairo, Cairo GovernorateAges 60 years+ - NCT07624513RecruitingPhase 3
Drug combination with planned stem cell transplant for newly diagnosed myeloma
This trial tests a combination of study drugs as the first treatment for newly diagnosed multiple myeloma, followed by maintenance based on your risk and response. It aims to improve outcomes while allowing some patients to postpone or avoid a stem cell transplant.
Boston, MassachusettsAges 18–75 - NCT07623941Recruiting
Focal Therapy Registry for Localized Prostate Cancer
This registry tracks men with early-stage prostate cancer who choose focal therapy—a targeted treatment that destroys only the cancer area while preserving healthy prostate tissue. The study helps doctors understand how well this approach works and its safety.
New York, New YorkAges 40–85 - NCT07623265Recruiting
Understanding Immunotherapy Response in Liver Cancer
This study collects tumor samples and medical information from patients with liver cancer to understand why some patients respond better to immunotherapy (immune-boosting drugs) than others. The goal is to improve treatment selection and outcomes for future patients.
AntwerpAges 18 years+ - NCT07622836Recruiting
Chemotherapy plus QL1706 for high-risk triple-negative breast cancer
This study tests whether adding a new immunotherapy drug called QL1706 to standard chemotherapy after surgery can help patients with aggressive triple-negative breast cancer that has spread to lymph nodes. The goal is to see if this combination prevents cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT07623473Recruiting
Blood test to help identify lung nodules as cancer or benign
This study tests whether a simple blood test can accurately identify whether a lung nodule (small spot) found on imaging is cancer or harmless. If it works, it could help doctors avoid unnecessary procedures and speed up diagnosis.
Gentofte MunicipalityAges Any age
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,069 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.