Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,232 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06768463Recruiting
Stomach cancer surgery after chemo for limited spread
This trial tests if surgery to remove the stomach and some tumors, after a few months of chemo, helps people whose stomach cancer has spread to only a few nearby spots (like the lining of the belly, liver, or lymph nodes) live longer compared to chemo alone.
Ho Chi Minh City, Ho Chi MinhAges 18–75 - NCT06891651Recruiting
21-gene testing for older breast cancer patients with lymph node spread
This trial looks at using a 21-gene test to guide treatment decisions for women aged 65 or older who have breast cancer that has spread to lymph nodes. It aims to see if this test can help avoid unnecessary chemotherapy in this group.
Jinan, ShandongAges 65 years+ - NCT06941857RecruitingPhase 2
Immunotherapy plus chemotherapy for advanced pancreatic cancer
This trial tests a new combination of drugs (NC410 plus chemotherapy and nivolumab, with or without ipilimumab) for people with metastatic pancreatic cancer who haven't had treatment yet. The goal is to see if adding these immunotherapy agents can help shrink or control the tumor.
Baltimore, MarylandAges 18 years+ - NCT07025785Recruiting
Testing for tumor DNA in blood after early-stage breast cancer surgery
This study looks for tiny bits of tumor DNA in your blood after surgery to see if it can help guide future treatment. It's for people who had surgery first (not chemotherapy before surgery) and have not seen the cancer spread.
Chapel Hill, North CarolinaAges 18 years+ - NCT07038304RecruitingPhase 2
Radiation for cancer growth in prostate cancer that stopped responding to hormones
This trial tests whether giving precise radiation to a few spots of cancer growth can help control prostate cancer that has stopped responding to hormone therapy. It is for people with up to 3 growing or new spots of cancer on a special scan.
GroningenAges 18 years+ - NCT07044362Recruiting
Histotripsy plus chemo vs. chemo alone for advanced liver-only colorectal cancer
This trial tests whether adding histotripsy—a non-invasive ultrasound treatment that destroys liver tumors—to standard chemotherapy improves outcomes for people with advanced colorectal cancer that has spread to the liver. It may be an option if your cancer is mainly in the liver and you are starting or have recently had chemotherapy.
Cleveland, OhioAges 18 years+ - NCT07112599Recruiting
AI predicts lymph node spread in high-risk prostate cancer
This study uses artificial intelligence to examine MRI and other health data to better predict if high-risk prostate cancer has spread to nearby lymph nodes. Researchers hope this will help guide treatment decisions.
Hefei, AnhuiAges 50 years+ - NCT07128680RecruitingPhase 1
Immunotherapy with or without a gut bacteria pill for kidney cancer
This trial tests whether adding a live bacteria pill (EXL01) to standard immunotherapy drugs (nivolumab and ipilimumab) helps treat advanced or metastatic kidney cancer that has clear cells. You may join if you have not had prior immunotherapy and your cancer has not been treated before (except possibly after surgery).
Duarte, CaliforniaAges 18 years+ - NCT07142122Recruiting
Comparing two types of stomach surgery for early upper gastric cancer
This trial compares two laparoscopic surgeries for early-stage stomach cancer in the upper part of the stomach. It looks at whether preserving a nerve (celiac branch of vagus nerve) during surgery leads to better recovery while still removing the cancer safely.
Fuzhou, FujianAges 18–75 - NCT07330544RecruitingPhase 2
Study of entinostat with anlotinib or fulvestrant for advanced breast cancer
This trial tests adding entinostat (a drug that may help hormone therapy work better) to anlotinib or fulvestrant for people with HR-positive, HER2-negative advanced breast cancer that has worsened after prior hormone therapy and a CDK4/6 inhibitor. It aims to find a new treatment option for those who cannot use chemotherapy yet.
Zhejiang, HangzhouAges 18 years+ - NCT06150417RecruitingPhase 2
Study of extra radiation for prostate cancer spread to few spots
This study tests whether adding a type of high-precision radiation (MDRT) to standard hormone therapy works better for men with prostate cancer that has spread to just a few places. It is for patients who are newly diagnosed and on long-term hormone therapy.
Cleveland, OhioAges 18 years+ - NCT00899301Recruiting
Banking breast cancer and related tissue samples for future studies
This study collects and stores tissue and fluid samples from people with a breast lump or breast cancer so researchers can study cancer biology in the future. It may help future patients by allowing better lab tests and research on why breast cancer starts, grows, and comes back.
Nashville, TennesseeAges 18 years+ - NCT07528209RecruitingPhase 3
Chemotherapy with or without immunotherapy for advanced rectal cancer
This study tests whether adding an immunotherapy drug (pucotenlimab) to standard chemotherapy (CAPOX) before surgery helps treat locally advanced rectal cancer better. The goal is to shrink tumors and improve survival while preserving bowel function when possible.
Guangzhou, GuangdongAges 18–75 - NCT07565532Recruiting
Small Cell Lung Cancer Treatment Study With Radiation
This study follows patients with small cell lung cancer who receive radiation therapy combined with other treatments. Researchers will track how well the treatment works and how patients respond over time to help improve future care.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07671339RecruitingPhase 1
Vaccine for pancreatic cancer with KRAS mutations
This trial tests a cancer vaccine (ELI-002 7P) for people with pancreatic cancer that hasn't spread to other parts of the body. It may be given alone or with another drug (tislelizumab) that helps the immune system fight cancer. The goal is to see if these treatments can help keep the cancer from coming back after surgery or chemotherapy.
Basking Ridge, New JerseyAges 18 years+ - NCT07533825Enrolling by invitation
Minimally Invasive Surgery Staging for Advanced Stomach Cancer
This trial tests whether a minimally invasive camera-guided surgical procedure (laparoscopy) can better detect hidden cancer spread in patients with advanced stomach cancer. The goal is to help doctors plan the best treatment and improve outcomes.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07429760Enrolling by invitation
Bowel prep with or without antibiotics for left-sided colon surgery
This study compares two ways to prepare for left-sided colorectal cancer surgery: cleaning the bowel with liquid alone, or cleaning the bowel plus taking oral antibiotics beforehand. The goal is to see if adding antibiotics reduces infections after surgery.
Lahore, Punjab ProvinceAges 18–60 - NCT07372261Enrolling by invitation
Predicting breast cancer spread risk
This study tests a method to predict if early-stage breast cancer might spread to other parts of the body. It uses leftover tumor tissue to help doctors plan your treatment.
San Giovanni Rotondo, FGAges 18 years+ - NCT06650748Enrolling by invitationPhase 2
A study of hormone therapy with or without a targeted drug for breast cancer
This trial tests if adding a targeted drug (CDK4/6 inhibitor) to hormone therapy works better than hormone therapy alone for women with a certain type of breast cancer (HR+/HER2-). The study measures the activity of tumor cells (Ki-67) to help decide treatment.
BeijingAges 18–70 - NCT06312137RecruitingPhase 3
Pembrolizumab with or without another drug for lung cancer after surgery
This trial tests adding a new drug (sacituzumab tirumotecan) to pembrolizumab for people with non-small cell lung cancer that did not completely disappear after initial treatment and surgery. The goal is to see if the combination works better than pembrolizumab alone.
Little Rock, ArkansasAges 18 years+ - NCT07549412RecruitingPhase 3
New chemotherapy drugs for advanced colorectal cancer
This trial tests whether a new chemotherapy combination (precemtabart tocentecan, with or without bevacizumab) works better than a standard treatment for colorectal cancer that has spread and stopped responding to previous drugs. The goal is to find treatments that help people live longer with fewer side effects.
Lone Tree, ColoradoAges 18 years+ - NCT06084234RecruitingPhase 4
National liver cancer screening trial
This trial is testing a new way to screen for liver cancer in people with cirrhosis or chronic hepatitis B. It aims to find cancer earlier so it can be treated more effectively.
Los Angeles, CaliforniaAges 18–85 - NCT05573893Recruiting
Real-world study of trastuzumab deruxtecan for HER2 breast cancer
This study looks at how people feel (patient-reported outcomes) and their real-world health data while they receive trastuzumab deruxtecan for advanced HER2-positive, HER2-low, or HER2-ultralow breast cancer. It helps researchers understand what outcomes happen outside of tightly controlled clinical trials.
AmbergAges 18–130 - NCT07304934Recruiting
New blood test model to check lymph node status in breast cancer
This study uses a blood test and imaging to predict whether breast cancer has spread to underarm lymph nodes, helping guide surgery. It may reduce unnecessary lymph node removal.
Hangzhou, ZhejiangAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,232 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.