Clinical trials · San Jose, CA
Cancer clinical trials in San Jose
We’re tracking 247 recruiting cancer studies with a site in or near San Jose — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near San Jose
- NCT04888975Recruiting
Device study for one-arm swelling after lymph surgery
This study tests a medical device (Dayspring Technology) to reduce swelling in the arm caused by breast cancer treatment and lymph surgery. You may be eligible if you have one-sided arm swelling after lymphatic surgery and meet safety checks for the device.
Palo Alto, CaliforniaAges 18 years+ - NCT05564377RecruitingPhase 2
Find targeted cancer treatments using genetic testing
This study matches people with advanced solid tumors to targeted treatment plans based on genetic testing. It also requires tumor sample testing to help doctors choose the most promising therapy for your specific tumor changes.
Palo Alto, CaliforniaAges Any age - NCT07044505Recruiting
Studying Uterine Fluid During Gynecologic Surgery
This study collects fluid from the uterus during gynecologic surgery to study cells and molecules, which may help understand how women's health conditions develop.
Palo Alto, CaliforniaAges 18 years+ - NCT06661915RecruitingPhase 2
Combination treatment for advanced myeloproliferative neoplasms
This study tests whether adding a new drug called iadademstat to the standard treatment ASTX727 helps people with advanced myeloproliferative neoplasms (blood cancers that cause the bone marrow to make too many cells). The goal is to see if the combination is safe and works better than the standard treatment alone.
Palo Alto, CaliforniaAges 18 years+ - NCT05919264RecruitingPhase 1/Phase 2
FOG-001 for advanced solid tumors with certain gene changes
This trial tests a new drug, FOG-001, alone or with other treatments, for people with advanced solid tumors that have specific changes in the WNT pathway genes. It aims to see if the drug can shrink tumors or slow their growth.
Palo Alto, CaliforniaAges 18 years+ - NCT07022470RecruitingPhase 2
Comparing 3 vs. 4 brachytherapy sessions for cervical cancer
This trial compares two different schedules of brachytherapy (a type of internal radiation) for cervical cancer. It aims to see if a shorter course of 3 treatments works just as well as the standard 4 treatments, which could mean fewer visits and less discomfort.
Palo Alto, CaliforniaAges 18 years+ - NCT05705219Recruiting
3D ultrasound scan to guide treatment decisions in liver cancer
This study tests whether a special 3D ultrasound scan (using contrast) can help support decisions for people with colorectal cancer that has spread to the liver. If you have planned new cancer treatment, the scan may add information to help doctors guide care.
Palo Alto, CaliforniaAges 18 years+ - NCT07343024Recruiting
Finding a Personalized Drug for Advanced Cancer
This trial looks at whether drugs not usually used for your type of cancer can help you. It matches your tumor's test results to possible treatments and works with your doctor to try one.
Palo Alto, CaliforniaAges Any age - NCT07106762RecruitingPhase 2/Phase 3
Study of new targeted drug vs chemo for bladder cancer
This trial tests a new drug called Izalontamab Brengitecan (a targeted therapy that delivers chemo straight to cancer cells) against standard platinum chemotherapy for people whose bladder cancer worsened after immunotherapy. It may be an option if you are fit for chemo but haven't had platinum chemo recently.
Palo Alto, CaliforniaAges 18 years+ - NCT07035418Recruiting
Young adults' role in cancer care decisions
This study looks at how much young people with cancer (ages 15–29) want to be involved in making decisions about their care. It's for those currently on treatment, at end of life, or who finished treatment up to a year ago.
Palo Alto, CaliforniaAges 15–29 - NCT06475989RecruitingPhase 3
Targeted therapy vs. chemotherapy for thyroid cancer
This trial compares a targeted therapy pill combination (dabrafenib and trametinib) with cabozantinib or chemotherapy for people with a specific type of advanced thyroid cancer (differentiated thyroid cancer) that has a BRAF V600E mutation. It aims to find which treatment works better after previous treatments have stopped working.
Palo Alto, CaliforniaAges 18 years+ - NCT06982521RecruitingPhase 3
Comparing two drug combinations for advanced breast cancer
This trial tests two different combinations of medicines for people with a certain type of advanced breast cancer (HR-positive, HER2-negative) that has a specific gene change called PIK3CA. The goal is to see which combination is better at slowing down the cancer.
Palo Alto, CaliforniaAges 18 years+ - NCT06793215RecruitingPhase 3
Divarasib plus pembrolizumab for KRAS G12C lung cancer
This trial compares a new targeted drug (divarasib) combined with an immunotherapy (pembrolizumab) versus standard chemotherapy plus immunotherapy for people with advanced lung cancer that has a specific KRAS G12C mutation. It aims to see if the new combination works better and is safe.
Palo Alto, CaliforniaAges 18 years+ - NCT05563766RecruitingPhase 2
Itraconazole with standard treatment for esophageal cancer
This trial tests whether adding the antifungal drug itraconazole to the usual chemotherapy and radiation before surgery can improve the chance of no cancer cells remaining at surgery. It is for patients with esophageal or gastroesophageal junction cancer that can be surgically removed.
Palo Alto, CaliforniaAges 18 years+ - NCT07505771RecruitingPhase 1
A study of 177Lu-IM-3050 for advanced solid tumors
This trial tests a new treatment called 177Lu-IM-3050 for people with advanced solid tumors that have not responded to or stopped working with standard treatments. The treatment targets a protein called FAP found on some cancer cells and may help shrink tumors or slow their growth.
Palo Alto, CaliforniaAges 18 years+ - NCT06690775RecruitingPhase 2
Study of a new drug for platinum-resistant ovarian cancer
This trial tests an investigational drug called TORL-1-23 for people with ovarian cancer that has stopped responding to platinum chemotherapy. It aims to see if the drug can help shrink or control the cancer.
Palo Alto, CaliforniaAges 18 years+ - NCT07616856Recruiting
Evaluating LumiSystem for cancer surgery margins
This study tests a device called LumiSystem that helps doctors check if all cancer cells are removed during breast cancer surgery. The goal is to see if using it improves surgery outcomes.
Palo Alto, CaliforniaAges 18 years+ - NCT04546399RecruitingPhase 2
Blinatumomab with or without nivolumab for first relapse ALL
This study compares blinatumomab alone versus blinatumomab plus nivolumab in young people whose B-cell ALL has returned for the first time. It aims to see whether adding nivolumab improves control of the leukemia after relapse.
Palo Alto, CaliforniaAges 1–30 - NCT05833360Recruiting
Blood test study to match cancer patients to treatment
This study collects a small amount of your blood to analyze cancer signals and sort patients by cancer “size and stage.” The goal is to see whether this blood-based information can help guide cancer care more accurately.
Palo Alto, CaliforniaAges 18 years+ - NCT07173751RecruitingPhase 3
Pumitamig for advanced triple-negative breast cancer
This study tests a new drug called pumitamig for people with a type of breast cancer that is triple-negative or has very low hormone receptors and has come back or spread. It aims to see if pumitamig works better than standard treatment and how safe it is for people who cannot get PD(L)-1 immunotherapy with chemo.
Palo Alto, CaliforniaAges 18 years+ - NCT05270213RecruitingPhase 1
RBS2418 for advanced cancers after standard treatments
This early-phase study tests RBS2418 in people with advanced, metastatic solid tumors that have not responded to standard treatment. It aims to see if the drug can shrink tumors or help control disease, and to learn what doses are safest.
Palo Alto, CaliforniaAges 18 years+ - NCT05406167Recruiting
Tracking quality of life during radiotherapy with a new system
This study collects information about how you feel and how treatment is delivered while you receive radiotherapy using the RefleXion Medical radiotherapy system. It may help doctors improve care and better understand what affects quality of life during treatment.
Palo Alto, CaliforniaAges Any age - NCT02660645Recruiting
Blue light bladder scan for suspected bladder cancer
This trial uses a special blue-light camera during a bladder procedure to help doctors better see non-muscle-invasive bladder cancer. It may help find cancer spots more clearly so they can be treated sooner.
Palo Alto, CaliforniaAges 18 years+ - NCT05997615RecruitingPhase 1
Study of VIR-5500 for advanced prostate cancer
This trial tests VIR-5500 (AMX-500), a new targeted treatment, in men with prostate cancer that has spread and stopped responding to standard therapies. The goal is to see if it is safe and if it may help shrink or slow the cancer.
Palo Alto, CaliforniaAges 18 years+
Hear when a new Cancer trial opens near San Jose, CA
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Cancer trials in other cities
Where these studies are running near San Jose
Institutions with a site for the recruiting cancer studies listed above.
- Stanford University · 8 studies
- Stanford Cancer Institute · 4 studies
- Stanford University School of Medicine · 3 studies
- VA Palo Alto Health Care System · 2 studies
- Cancer Commons
- Dung Nguyen, MD, PharmD
- Epic Care-Dublin
- Exai Bio Inc.
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cancer studies in California.
Common questions
- Are there cancer clinical trials near San Jose?
- Yes. We're currently tracking 247 recruiting cancer studies with a site near San Jose, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study near San Jose?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in San Jose to take part?
- Not necessarily. These studies have a site near San Jose, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open near San Jose regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.