Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 12,855 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05736419RecruitingPhase 2
Immune-suppressing treatment before stem cell transplant for blood disorders
This Phase 2 study tests an immune-suppressing treatment for people with sickle cell disease or beta-thalassemia who are preparing for a stem cell transplant from a donor. It aims to help the transplant work better by changing the immune response.
Basking Ridge, New JerseyAges 2–50 - NCT05733091Recruiting
Study of symptoms and function after certain head and neck cancers
This study looks at how symptoms and everyday functioning change for people with cancers of the nose/sinuses, the throat behind the nose (nasopharynx), or nearby skull-base areas. It may help doctors understand what survivors experience and improve long-term care.
Houston, TexasAges 18 years+ - NCT05726747Recruiting
Quality-of-life study for fluid buildup and muscle loss
This trial studies people with recurring fluid buildup in the belly (ascites) and looks at how treatments or supportive care affect quality of life and muscle strength. It may help researchers better understand which approaches improve day-to-day well-being when ascites keeps coming back.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05739331Recruiting
AI-assisted breathing test to check swollen chest lymph nodes
This trial uses an AI-supported breathing procedure to help doctors examine enlarged lymph nodes in the chest when the cause is still unknown. It may help improve how accurately and efficiently doctors assess these lymph nodes so you can get answers sooner.
LevangerAges 18 years+ - NCT05720338RecruitingPhase 3
Does everyone need a drain after distal pancreas surgery?
This study compares whether patients need an internal abdominal drain after removing part of the pancreas (a distal pancreatectomy). It aims to see if skipping the drain is as safe and may reduce drain-related problems.
Cleveland, OhioAges 18 years+ - NCT05715684Recruiting
Pre-surgery preparation program for people having bladder removal
This study tests a patient-centered coaching and preparation program before bladder surgery (cystectomy) to help you get ready for surgery and recovery. It may be especially helpful for people having urinary diversion using an ileal conduit or ileal neobladder.
Boston, MassachusettsAges 18–85 - NCT05710861Recruiting
Focal HIFU versus prostate surgery: cost and quality of life
This trial compares focal HIFU (a targeted heating treatment inside the prostate) with prostate surgery, looking at overall cost and quality of life. It may help people with certain early, limited prostate cancers understand which option fits best for them.
BesançonAges 50–75 - NCT05727787Recruiting
Radiation trial for liver cancer that cannot be removed
This Phase I study tests a specific radiation approach (vGRID SBRT) for hepatocellular carcinoma (and some mixed types) that is advanced and cannot be cured with surgery or transplant. It aims to control tumors while staying within safety limits for the liver and nearby organs.
Kansas City, KansasAges 18 years+ - NCT05714111Recruiting
Registry for pancreatic cancer patients and people being evaluated
This is a research registry that collects information from adults with suspected or diagnosed pancreatic cancer. It may help doctors better understand the disease and improve care over time.
MilanAges 18 years+ - NCT05731726RecruitingPhase 2
New treatment before surgery for locally advanced rectal cancer
This trial tests whether giving serplulimab (an immune medicine) plus CAPEOX chemotherapy and celecoxib before surgery can shrink locally advanced rectal cancer and improve outcomes. It may help by increasing immune attack on the tumor while chemotherapy helps reduce the cancer before the operation.
Hangzhou, ZhejiangAges 18–75 - NCT05745038Recruiting
Social support program for people with advanced cancer
This trial tests a social network support intervention to help people with advanced or likely incurable cancer stay connected and supported. It includes the patient and up to 10 people they choose as their support network.
Rochester, New YorkAges 60 years+ - NCT05714072RecruitingPhase 1
Ruxolitinib plus abemaciclib for myelofibrosis after ruxolitinib
This trial tests whether adding abemaciclib to ongoing ruxolitinib can better control myelofibrosis in people who are not getting enough benefit from ruxolitinib alone. It is designed to see safety and response in a specific group with intermediate-2 or high-risk disease and ongoing symptoms or enlarged spleen.
Basking Ridge, New JerseyAges 18 years+ - NCT05738005Recruiting
Tracking food intake in people with amyloidosis
This study checks how people with amyloidosis record what they eat and how consistently they can do it using a phone app. Your participation may help researchers better understand dietary patterns in amyloidosis over time.
Detroit, MichiganAges 18 years+ - NCT05722886RecruitingPhase 2/Phase 3
Screening trial for rare cancer gene changes in existing medicines
This trial checks whether existing cancer medicines can help people whose tumors have specific “gene changes” (mutations). You may be assigned to a treatment arm that matches your tumor’s gene results after fresh biopsy and blood testing.
BelfastAges Any age - NCT05740787Recruiting
Study of thinking changes after chemotherapy for breast cancer
This study looks at how chemotherapy may affect thinking and memory in people with HER2-negative breast cancer. It uses brain scans during or after chemotherapy to understand these changes and potentially guide support in the future.
AberdeenAges 18 years+ - NCT05713006RecruitingPhase 1/Phase 2
Alectinib drug handling study for ALK-positive advanced lung cancer
This early-phase trial studies how alectinib (an ALK-blocking medicine) moves through the body and how it’s tolerated in people with advanced non-small cell lung cancer (NSCLC) that has an ALK rearrangement. You may be considered if you have ALK-positive, recurrent or advanced disease and have already had specific prior treatments.
Mexico City, Mexico CityAges 18 years+ - NCT05733689RecruitingPhase 1
Testing new pre-surgery treatment for stomach and esophagus cancer
This Phase 1 trial tests how well a tailored (response-adapted) chemotherapy plan works before surgery for stomach or gastroesophageal junction cancer. It aims to improve treatment planning while checking early safety.
Orange, CaliforniaAges 18 years+ - NCT05735717RecruitingPhase 2
T-cell transplant using depleted receptors for blood cancers
This Phase 2 study tests a specialized stem cell transplant that removes certain immune “T-cell” receptors to help treat blood cancers like acute leukemia. It may help your body rebuild a healthier immune system after high-dose treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT05710679Recruiting
Blood test predicts leftover cancer after intensified head and neck radiation
This study uses a blood test to see whether cancer DNA is still detectable after a stronger combination of radiation and chemotherapy for locally advanced head and neck cancer. The goal is to predict who may have “residual” (remaining) disease and help guide future care.
Clermont-Ferrand, Puy-de-DômeAges 18–80 - NCT05739591Recruiting
Long-term follow-up for people treated in a breast cancer trial
This study checks how well a previous early breast cancer treatment works over the long term and monitors safety. It may help you and future patients by providing long-term results from the original trial.
Innsbruck, TriolAges 18 years+ - NCT05709782RecruitingPhase 2
MR-guided targeted radiation for limited-spine spinal metastasis
This Phase 2 study tests an MRI-guided radiation machine (an MR LINAC) to deliver very focused treatment to spine tumors. It may help by improving accuracy while treating up to a small number of spine levels affected by cancer.
Houston, TexasAges 18 years+ - NCT03760575RecruitingPhase 1
Pembrolizumab plus chemo with surgery for pleural mesothelioma
This trial studies how well pembrolizumab (an immune therapy) works when added to chemotherapy before image-guided surgery for malignant pleural mesothelioma. It aims to shrink or control the cancer and improve surgical results by combining treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05301283RecruitingPhase 2
Adaptive radiation therapy before surgery for soft-tissue sarcoma
This trial tests a personalized (“adaptive”) radiation plan before surgery for high-grade soft-tissue sarcoma that can be removed. It may help shrink the tumor and improve how well surgery can treat the cancer.
Tampa, FloridaAges 18 years+ - NCT05194397RecruitingPhase 2
Exercise plus NR supplement to boost fitness after stem-cell transplant
This trial tests whether a supervised exercise program, plus an NR supplement, can improve fitness in young people who have had an allogeneic (donor) stem-cell transplant for certain blood cancers or bone marrow conditions. It’s meant to help with energy and physical ability while monitoring safety.
Duarte, CaliforniaAges 10–30
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 12,855 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.