Clinical trials
Cannabis Use Disorder clinical trials
Below are recruiting cannabis use disorder clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07489443Recruiting
Helping pregnant women reduce tobacco and cannabis use
This study is testing a program to help pregnant women and new mothers cut back on or quit using tobacco and cannabis. It’s designed to see if the program is easy to use and helps improve health for both mom and baby.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07464613Recruiting
Social thinking in severe alcohol use disorder
This study looks at how people with severe alcohol use disorder process social information, like understanding others' emotions or intentions. It uses brain imaging (MRI) and tests on a smartphone. The goal is to learn more about social cognition in recovery.
Reims, ReimsAges 18–65 - NCT07420283RecruitingPhase 2
Study of Brenipatide for opioid use disorder
This trial tests a new medicine called Brenipatide for people with opioid use disorder who are already taking buprenorphine but still occasionally use non-prescribed opioids. It aims to see if the study drug can help reduce opioid use.
Phoenix, ArizonaAges 18–75 - NCT07218471Recruiting
Cannabis reduction study for heavy users
This study tests if helping people reduce heavy cannabis use improves daily life. It's for adults with cannabis use disorder who want to cut back.
Charleston, South CarolinaAges 18 years+ - NCT07210268Recruiting
Brain stimulation for nicotine addiction treatment
This trial tests a new method called temporal interference to stimulate the brain and help people who vape nicotine reduce their addiction. It aims to see if this non-invasive approach can make it easier to quit.
Bloomington, IndianaAges 21–50 - NCT06105853Recruiting
Stress and brain activity in alcohol use disorder
This study looks at how people with alcohol use disorder respond to stress and what happens in the brain. You'll use a smartphone and may have an MRI scan to understand your stress responses.
Mannheim, Baden-WurttembergAges 18–65 - NCT07044466Recruiting
Social functioning study for people in treatment for opioid use
This study looks at how people recovering from opioid use disorder get along with a close friend or family member (called a CSO). It may help improve social support during early treatment.
Charleston, South CarolinaAges 18 years+ - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT06907979Recruiting
Cannabis use and emotion processing study
This study looks at how heavy cannabis use affects the way you process emotions. You may be able to join if you use cannabis most days, meet criteria for cannabis use disorder, and are not currently in treatment for it. Participants will have brain scans and mild brain stimulation.
Auburn, AlabamaAges 18–50 - NCT06688539RecruitingPhase 4
Quitting e-cigarettes in adults who also use cannabis
This trial tests if varenicline, a stop-smoking medication, can help people ages 18 to 40 quit e-cigarettes while also using cannabis. It's designed for regular e-cigarette users who want to quit and who use cannabis at least 10 days per month.
Charleston, South CarolinaAges 18–40 - NCT06643988Recruiting
Memory and thinking study for opioid use disorder
This study looks at how people with opioid use disorder remember personal events. You'll do tasks on a cellphone and at home while taking medication for opioid use disorder.
Philadelphia, PennsylvaniaAges 18–60 - NCT06381180RecruitingPhase 1/Phase 2
Cannabis for Veterans with PTSD
This study is testing whether cannabis can help veterans with PTSD feel better. It is for veterans who have used cannabis before and currently have PTSD symptoms.
Detroit, MichiganAges 19–69 - NCT06320366Recruiting
Faster TMS for methamphetamine use disorder
This study tests a faster brain stimulation technique (TMS) to help people reduce methamphetamine use. It may be a good option if you have moderate to severe methamphetamine use disorder and are looking for new treatment approaches.
Aurora, ColoradoAges 21–65 - NCT06239350Recruiting
Young adult tobacco and cannabis co-use study
This study tests a program to help young adults who use both nicotine and cannabis products reduce or quit nicotine use. If you are between 18 and 25, use nicotine products at least 20 days a month and cannabis at least 10 days a month, and want to quit nicotine, you may be eligible.
Charleston, South CarolinaAges 18–25 - NCT06058702RecruitingPhase 1
Genetics of cannabis use disorder and response
This study looks at how genes affect cannabis use disorder and how people respond to cannabis. It may help explain why some people develop problems with cannabis while others do not.
West Haven, ConnecticutAges 21–60 - NCT05988632RecruitingPhase 1/Phase 2
Insulin nasal spray for alcohol use disorder
This trial tests whether a nasal spray with insulin can help people with alcohol use disorder. It may affect how the brain responds to alcohol and reduce drinking.
Providence, Rhode IslandAges 21 years+ - NCT05781009RecruitingPhase 2
Pregnenolone treatment for alcohol use disorder
This Phase 2 study tests pregnenolone to help reduce or improve alcohol use disorder symptoms. It looks for adults who drink regularly and meet diagnostic criteria for moderate to severe alcohol use disorder, while excluding people with certain other substance use, medicines, or serious mental/medical conditions.
New Haven, ConnecticutAges 18–70 - NCT05515354RecruitingPhase 4
Smoking quit plan matched to your menstrual cycle phase
This Phase 4 study tests a smoking-quit treatment plan timed to your menstrual cycle. It may help you quit smoking and learn how quitting support works for people who menstruate regularly.
Toronto, OntarioAges 18–40 - NCT05452772RecruitingPhase 2
Psilocybin plus niacin to help quit smoking
This Phase 2 study tests whether a psilocybin “session” with niacin can help people quit smoking. It’s for adults who smoke daily and want to quit but have tried and struggled before.
Birmingham, AlabamaAges 21 years+ - NCT05011760RecruitingEarly Phase 1
PET brain scan with a cocaine-use disorder medicine test
This early-phase study uses a PET brain scan (a special imaging test) to see how the brain responds in people with cocaine use disorder. It aims to better understand brain activity and whether this scan approach could help research or future treatments.
Pittsburgh, PennsylvaniaAges 18–55 - NCT03470480Recruiting
Brain stimulation for methamphetamine cravings
This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce cravings for methamphetamine in people who have stopped using it for at least 4 weeks. If you are trying to stay off methamphetamine and struggling with cravings, this treatment might help.
Portland, OregonAges 18–65 - NCT07684976Recruiting
Safety of a helmet device using ultrasound for substance use disorder
This study tests a special helmet that uses focused ultrasound to stimulate parts of the brain involved in addiction. It aims to see if the treatment is safe and works for people with moderate to severe substance use disorder who have not gotten enough help from standard medication treatments.
Toronto, OntarioAges 18–70 - NCT07559500RecruitingPhase 1
Study of tirzepatide for alcohol use disorder
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Bethesda, MarylandAges 21–65 - NCT07279558RecruitingPhase 2
CBD and Alcohol Use Study
This study tests whether cannabidiol (CBD), a compound from cannabis, can help people who drink alcohol regularly reduce their drinking or change their drinking patterns. You may be eligible if you're 21-65, have used CBD or cannabis before, drink alcohol regularly, and don't take certain medications that could interfere.
Aurora, ColoradoAges 21–65
Hear when a new Cannabis Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cannabis use disorder?
- Yes. Clin2 currently lists 150 recruiting cannabis use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.