Clinical trials
Cannabis Use Disorder clinical trials
Below are recruiting cannabis use disorder clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06395467Recruiting
Integrated treatment for teens with substance use disorder
This trial tests a treatment program for teens and young adults with substance use disorders. It includes family members and is designed to support recovery and personal growth.
Farmington, ConnecticutAges 14–21 - NCT06395389Recruiting
A brief program to help young adults cut back on cannabis
This trial tests a short, one-time program designed to help people ages 18-25 who use cannabis frequently (at least 20 days per month) reduce their use. It may be a good fit if you're not already in treatment and are thinking about making a change.
Charleston, South CarolinaAges 18–25 - NCT06259916Recruiting
EEG to tell alcohol vs. cannabis intoxication
This study uses electroencephalography (EEG) to see if brain activity can tell whether you are drunk, high, or both. Results might help improve safety in the future.
Fort Collins, ColoradoAges 21–50 - NCT06107062RecruitingPhase 2
CBD treatment for cannabis concentrate users
This trial tests CBD as a potential treatment for heavy cannabis concentrate users who want to cut down or quit. You would take CBD daily and attend regular visits to track your progress.
Boulder, ColoradoAges 21 years+ - NCT06124846Recruiting
Cannabis break and brain changes in teens
This study looks at what happens in the brain when teens with cannabis use disorder stop using cannabis for 6 weeks. It uses MRI scans to see changes in areas that control habits and decisions.
Minneapolis, MinnesotaAges 15–18 - NCT05885542RecruitingPhase 1/Phase 2
Testing CBD pills for cannabis use and stress in young adults
This early-phase study tests whether a CBD pill (compared with a placebo sugar pill) can affect cannabis use and stress in people ages 18–25 who use cannabis very frequently. It may help your stress levels and cannabis-related symptoms while researchers carefully monitor safety and abstinence periods during visits.
Charleston, South CarolinaAges 18–25 - NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65 - NCT05855668Recruiting
Study how brain and behavior differ in alcohol and cannabis use
This study looks at how people’s thoughts, brain-related measures, and behaviors differ between alcohol use disorder and cannabis use disorder. You may be asked to join group psychotherapy and complete assessments, which could help improve how care is planned for people like you.
Toronto, OntarioAges 18 years+ - NCT05729932RecruitingPhase 1
Cannabis and opioid use disorder study
This Phase 1 trial studies cannabis in people with opioid use disorder. The goal is to better understand how it may affect opioid use disorder, while monitoring safety.
Lexington, KentuckyAges 18–55 - NCT05472818RecruitingEarly Phase 1
Imaging study for treating cannabis use disorder with a test dose
This early-phase study uses brain scans to study cannabis use disorder and looks at whether a treatment approach is suitable for people who use cannabis every day. It may help researchers understand brain changes related to quitting and recovery.
New Haven, ConnecticutAges 18–75 - NCT05486234Recruiting
Study to reduce cannabis and alcohol use with teen and caregiver
This study looks at ways to help teens cut down on cannabis and alcohol use. You may qualify if you’ve been using both in the last three months and your caregiver is able to join and consent.
Charleston, South CarolinaAges 13–17 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT05453513Recruiting
Study how depression and cannabis affect the brain in young adults with HIV
This study looks at brain activity to understand how depression and cannabis use may be linked in young adults living with HIV. It mainly involves questionnaires, mental health screening, and brain scans, which may help researchers better understand risk factors and brain “underpinnings.”
Miami, FloridaAges 18–59 - NCT05389930RecruitingPhase 2
Study how cannabis affects alcohol drinking
This Phase 2 study looks at whether using cannabis changes how much alcohol you drink. You may be able to take part if you’ve been drinking heavily and using cannabis recently and can meet health and screening requirements.
Providence, Rhode IslandAges 21–50 - NCT04871048Recruiting
tDCS training to reduce cannabis use in people with schizophrenia
This trial tests whether a non-painful brain stimulation method (tDCS) can help people with schizophrenia who also have moderate-to-severe cannabis use disorder reduce or quit cannabis. It also involves MRI scanning to help study brain changes.
BronAges 18–60 - NCT04197921Recruiting
Brain-focused ultrasound for opioid addiction-related substance use
This trial studies Exablate, a non-surgical brain treatment that aims to change activity in a specific brain area involved in cravings and substance use. It is meant for people in structured opioid or substance use treatment who are currently abstaining from opioids and other illicit drugs.
Tampa, FloridaAges 18–60 - NCT05899660Recruiting
Omega-3 for alcohol use disorder during withdrawal
This trial studies whether taking omega-3 supplements during a hospital alcohol-withdrawal program can improve recovery for people with alcohol use disorder. It may help by changing inflammation and how the body responds to stopping alcohol.
BrusselsAges 18–70 - NCT07829263Recruiting
Brain stimulation with talk therapy for cocaine use disorder
This study tests whether a non-invasive brain stimulation method (high-definition transcranial direct current stimulation, or HD-tDCS) combined with cognitive behavioral therapy (a type of talk therapy) can help people reduce cocaine use. It explores if this combination is safe and practical.
Richmond, VirginiaAges 18–65 - NCT07825818RecruitingEarly Phase 1
Brain scan study for heavy drinkers
This study uses a special brain scan to look at how alcohol use affects energy production in brain cells. It may help researchers find new ways to treat alcohol use disorder.
Pittsburgh, PennsylvaniaAges 18–55 - NCT07612631RecruitingEarly Phase 1
Brain imaging study of alcohol and stress response
This research uses brain imaging to understand how two brain systems—one involved in stress and one involved in reward—interact in people with alcohol use disorder. The goal is to find new ways to help people reduce heavy drinking.
Pittsburgh, PennsylvaniaAges 18–55 - NCT07520292RecruitingPhase 1
Testing NTX-2001 to reduce drinking in alcohol use disorder
This study tests whether a new medication called NTX-2001 can help people with alcohol use disorder drink less. Researchers will measure how the drug affects alcohol consumption and safety in adults aged 21–60.
New Haven, ConnecticutAges 21–60 - NCT07490600Recruiting
Testing brain stimulation and rewards for quitting cocaine
This trial combines deep transcranial magnetic stimulation (TMS) with a reward program (contingency management) to help people stop using cocaine. It may help if you are struggling with moderate to severe cocaine use and want a non-drug treatment.
Houston, TexasAges 18–65
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Common questions
- Are there clinical trials for cannabis use disorder?
- Yes. Clin2 currently lists 150 recruiting cannabis use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.