Clinical trials
Cannabis Use Disorder clinical trials
Below are recruiting cannabis use disorder clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05855668Recruiting
Study how brain and behavior differ in alcohol and cannabis use
This study looks at how people’s thoughts, brain-related measures, and behaviors differ between alcohol use disorder and cannabis use disorder. You may be asked to join group psychotherapy and complete assessments, which could help improve how care is planned for people like you.
Toronto, OntarioAges 18 years+ - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65 - NCT05885542RecruitingPhase 1/Phase 2
Testing CBD pills for cannabis use and stress in young adults
This early-phase study tests whether a CBD pill (compared with a placebo sugar pill) can affect cannabis use and stress in people ages 18–25 who use cannabis very frequently. It may help your stress levels and cannabis-related symptoms while researchers carefully monitor safety and abstinence periods during visits.
Charleston, South CarolinaAges 18–25 - NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT06084520Recruiting
Pain questionnaire study for opioid and non-opioid patients
This study tests two questionnaires for people with long-term pain. Researchers want to see if the tools work well for both those taking opioids and those who are not. Your answers can help improve pain care.
Uppsala, UpplandAges 18–75 - NCT06225232RecruitingPhase 2
Psilocybin for cannabis use disorder
This trial tests whether a single dose of psilocybin (a psychedelic compound) can help people with moderate to severe cannabis use disorder reduce or stop their cannabis use. You will receive the drug in a supervised setting and have follow-up check-ins.
Hamilton, OntarioAges 18–65 - NCT06395467Recruiting
Integrated treatment for teens with substance use disorder
This trial tests a treatment program for teens and young adults with substance use disorders. It includes family members and is designed to support recovery and personal growth.
Farmington, ConnecticutAges 14–21 - NCT06609083RecruitingPhase 1
How cannabis affects cigarette smoking
This study looks at how cannabis affects cigarette smoking habits. If you smoke every day and also use cannabis weekly, researchers want to see if cannabis changes how much you smoke.
Baltimore, MarylandAges 21 years+ - NCT06609109RecruitingPhase 1
Testing how cannabis affects e-cigarette use
This study is for daily e-cigarette users who also use cannabis at least once a week. It tests how cannabis affects vaping behavior. Researchers want to see if using cannabis changes how much or how people vape.
Baltimore, MarylandAges 21 years+ - NCT06660381RecruitingPhase 1
Psilocybin therapy for cannabis use disorder
This study tests if psilocybin (a substance that can change how you think and feel) can help people reduce or stop using cannabis. You will receive support and be monitored closely throughout the trial.
Baltimore, MarylandAges 18 years+ - NCT06701487Recruiting
Brain learning mechanisms and substance use control
This study looks at how certain learning mechanisms in the brain (called Pavlovian conditioning) influence your ability to control alcohol or drug use. It may help explain why some people have trouble stopping, and could lead to better treatments. You'll fill out questionnaires and likely have a brain scan (MRI).
DresdenAges 18–65 - NCT06878859Recruiting
Online program for depression and cannabis use
This study tests a digital (online) program designed to help people who struggle with both depression and cannabis use. If you're feeling down and also using cannabis more than you'd like, this program might help you manage both.
Boston, MassachusettsAges 18 years+ - NCT06883162RecruitingPhase 3
A study to help people stop smoking tobacco and reduce cannabis use
This study tests whether a medication called varenicline (or a placebo) can help people who use both tobacco and cannabis to quit or cut back. It takes place in South Carolina and lasts 12 weeks.
Charleston, South CarolinaAges 18 years+ - NCT06981195RecruitingPhase 2
Testing lemborexant for insomnia in people on buprenorphine
This study tests if the sleep medication lemborexant can help people with opioid use disorder who also have chronic insomnia. Participants must already be taking buprenorphine (Suboxone) for at least 4 weeks. The goal is to see if better sleep improves mood and reduces opioid use.
Richmond, VirginiaAges 18 years+ - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT07071779Recruiting
Online training to help young people resist alcohol or cocaine
This study tests a web-based training program to help teens and young adults (ages 14–35) improve their ability to say no to alcohol or cocaine. The training could make it easier to resist cravings during treatment.
BernAges 14–35 - NCT07091292Recruiting
Exercise as a treatment for cannabis use
This study tests whether regular exercise can help young adults reduce or stop their cannabis use. It may be a good fit if you are 18-40, use cannabis as your main drug, and want to try an exercise-based approach.
Hong KongAges 18–40 - NCT07184983Recruiting
Brain stimulation for cannabis use disorder
This study tests whether a gentle brain stimulation technique (called tDCS) can help people who want to cut down or stop using cannabis. You'll wear a headband-like device during sessions at NYU, and the study team will check in with you over time.
New York, New YorkAges 22–65 - NCT07340554Recruiting
Brain imaging study for teens who use cannabis
This study looks at the brains of teenagers who use cannabis using an MRI scanner. It aims to understand how cannabis affects the developing brain, which might help improve treatment options.
Indianapolis, IndianaAges 14–17 - NCT07523633RecruitingPhase 2
Semaglutide to help reduce cannabis use disorder
This trial tests whether a medication called semaglutide (used for weight management) can help adults with cannabis use disorder cut down or stop using cannabis. Researchers want to see if it reduces cravings and use while also monitoring overall health.
FrederiksbergAges 18–70 - NCT06381180RecruitingPhase 1/Phase 2
Cannabis for Veterans with PTSD
This study is testing whether cannabis can help veterans with PTSD feel better. It is for veterans who have used cannabis before and currently have PTSD symptoms.
Detroit, MichiganAges 19–69 - NCT07044466Recruiting
Social functioning in opioid use disorder
This study looks at how people starting buprenorphine treatment for opioid use disorder interact with others socially. It also involves a loved one (a friend or family member) who participates with you.
Charleston, South CarolinaAges 18 years+ - NCT05011760RecruitingEarly Phase 1
PET brain scan with a cocaine-use disorder medicine test
This early-phase study uses a PET brain scan (a special imaging test) to see how the brain responds in people with cocaine use disorder. It aims to better understand brain activity and whether this scan approach could help research or future treatments.
Pittsburgh, PennsylvaniaAges 18–55
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Common questions
- Are there clinical trials for cannabis use disorder?
- Yes. Clin2 currently lists 155 recruiting cannabis use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.