Clinical trials
Cardiac Disease clinical trials
Below are recruiting cardiac disease clinical trials, each written for real people, not researchers. We’re tracking 319 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT03992560Recruiting
Cardiac MRI-guided device implantation versus standard CRT
This trial compares two ways of placing a heart rhythm device: guiding the procedure with a cardiac MRI versus using the usual approach. It aims to see which method improves heart function and outcomes for people with a certain type of heart failure due to blocked heart arteries.
LondonAges 18 years+ - NCT07301489Recruiting
Heart study for lung screening participants
This trial adds a heart health check to an existing lung cancer screening study. It looks at old chest CT scans to assess heart disease risk and asks you to return for a follow-up visit one year later.
Lørenskog, AkershusAges 60–79 - NCT04882488Recruiting
Testing heart scan measurements in severe aortic valve narrowing
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Bad Oeynhausen, North Rhine-WestphaliaAges 65 years+ - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT06324149Recruiting
Frailty and aging conditions in chronic diseases
This study looks at how frailty affects the course of chronic diseases and how chronic diseases affect frailty. It may help understand aging-related conditions better.
MilanAges 18–100 - NCT06557616Recruiting
CoolCryo system for treating atrial fibrillation during mitral valve surgery
This trial tests a new tool called CoolCryo that freezes heart tissue to treat atrial fibrillation while you have mitral valve surgery. If you are already having this surgery and also have AF, this device could correct both problems at once.
BydgoszczAges 18 years+ - NCT07029503RecruitingPhase 2
Heart failure and kidney function study
This trial tests a new treatment for people with heart failure and severely reduced kidney function. It aims to see if the treatment can help protect both the heart and kidneys.
StockholmAges 18 years+ - NCT07468383Recruiting
Catheter ablation for slow heart rate study
This study tests a catheter procedure to treat a slow heart rate (bradycardia) that causes symptoms like dizziness or fainting. It may be an option for people who haven't had a pacemaker and whose heart can still speed up with medication.
Beijing, ChinaAges 18–65 - NCT06028165Recruiting
Heart bypass surgery planning with CT versus standard angiogram
This trial compares two ways to plan heart bypass surgery: a CT scan that measures blood flow (CT-FFR) versus the usual heart catheter X-ray (angiogram). It aims to see which method leads to better outcomes for people with blocked heart arteries.
Goyang-si, Gyeonggi-doAges 40–80 - NCT06077201Recruiting
Home-based heart rehab after valve procedure
This study tests a home-based exercise program using a mobile app and activity tracker for people who have had a heart valve procedure. It aims to help you safely recover and improve your fitness at home.
Nashville, TennesseeAges 18 years+ - NCT06597331Recruiting
Heart function study for COPD flare-ups
This study looks at how a COPD flare-up might affect the heart in people who haven't had a heart attack or known heart muscle damage before. It uses a simple heart ultrasound to check for stress-related changes.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT06347276Recruiting
PFO closure and brain microemboli study
This trial looks at whether closing a small hole in the heart (PFO) can reduce tiny clots traveling to the brain. It includes people who have had a stroke or migraine, and also those without symptoms but with high-risk features.
Beijing, Beijing MunicipalityAges 18–65 - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT06739005Recruiting
AI model to assess heart surgeon technique in bypass surgery
This study tests whether an artificial intelligence (AI) model can accurately evaluate the surgical technique of heart surgeons performing a common bypass procedure. If you are a first-time bypass patient and do not have certain heart or organ conditions, you may be able to participate and help improve surgical training tools.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07298122Recruiting
Heart imaging for hidden clots in ESUS stroke with left ventricular disease
This study uses advanced heart scans (MRI or CT) to look for blood clots in the heart of people who had a stroke with an unclear cause, specifically if they also have a mild heart condition affecting the left ventricle. The goal is to find hidden clots that might be causing strokes.
Milan, LombardyAges 18 years+ - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT07130968Enrolling by invitation
Heart and lung function study with exercise test and five-year follow-up
This study looks at how your heart and lungs work during exercise by using a special test called a cardiopulmonary exercise test (CPET). Researchers will follow you for up to five years to see how your health changes. It may help you understand your heart condition better and get more personalized care.
Guangzhou, GuangdongAges 18–80 - NCT06324682Recruiting
Comparing heart pacemaker types for better treatment
This trial looks at different ways to pace the heart (like left, right, or both sides) to see which works best for people who need a pacemaker. If you have a heart condition requiring a pacemaker, this study may help find the safest and most effective option for you.
Ferrara, FEAges 18 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT06479876Recruiting
Home-based heart rehab for heart failure
This study tests a home-based cardiac rehabilitation program for people with heart failure. It aims to help you become more active and manage your condition safely at home.
Nashville, TennesseeAges 18 years+ - NCT06699056Recruiting
AI heart monitor study for ejection fraction
This study uses an AI-powered wearable monitor to check how well your heart pumps blood (ejection fraction) from a simple EKG recording. It may help doctors quickly assess heart function without extra tests.
Orange, CaliforniaAges 18 years+ - NCT03775954Recruiting
Fetal heart testing in high-risk pregnancies after baby loss
This study checks unborn babies’ heart signals using special scans during pregnancy and then checks the baby’s heart shortly after birth. It may help researchers understand why certain high-risk pregnancies can lead to fetal demise and improve care.
Madison, WisconsinAges 18 years+
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Common questions
- Are there clinical trials for cardiac disease?
- Yes. Clin2 currently lists 319 recruiting cardiac disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.