Clinical trials
Cardiac Disease clinical trials
Below are recruiting cardiac disease clinical trials, each written for real people, not researchers. We’re tracking 313 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT07268170Enrolling by invitationPhase 2/Phase 3
Heart rate control before heart CT scan
This trial tests two medicines to lower heart rate before a cardiac CT scan in adults who need the scan. It is for people whose heart rate is naturally a bit fast (over 65 beats per minute) but not too fast (under 100 bpm).
HerningAges 30–80 - NCT07649330Recruiting
Myofascial Release for Heart Surgery Recovery
This study tests whether a hands-on soft-tissue massage technique can help reduce pain and stiffness in patients recovering from open-heart surgery. The goal is to see if it speeds up healing and improves quality of life after the procedure.
Kaohsiung CityAges 18 years+ - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT07314268Recruiting
Study of tiny blood particles in heart amyloidosis
This study looks at tiny particles called extracellular vesicles in the blood of people with a specific type of heart amyloidosis. It aims to find better ways to track the disease and predict outcomes.
São Paulo, São PauloAges 18 years+ - NCT07174206Recruiting
Smartwatch monitoring for heart patients
This trial tests a smartwatch tool to track heart rhythm and detect problems in people with heart disease. It may help find irregular heartbeats early during routine checkups.
São Paulo, São PauloAges 22 years+ - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Birmingham, AlabamaAges 18–85 - NCT07028593RecruitingPhase 4
Ciprofol for heart protection during lung surgery
This trial tests if a new sedative drug, Ciprofol, can reduce heart damage after non-cardiac surgery compared to standard care. It is for people aged 45–80 having planned lung surgery (like lobe removal or wedge resection) who will stay in the hospital for at least 3 days after the procedure.
WuhanAges 40–80 - NCT07775742Recruiting
Exercise programs after heart bypass surgery
This study compares two exercise programs for people who have recovered from heart bypass surgery. One program involves high-intensity interval training, and the other is a home-based rehabilitation program. The goal is to see which program helps improve recovery and overall health.
MadinahAges 55–58 - NCT07695363Recruiting
Restrictive fluids in liver transplant
This trial tests if giving less fluid during liver transplant surgery helps recovery. It is for adults with end-stage liver disease receiving a transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT06908759Recruiting
Fall risk in older adults after heart rehab
This study looks at whether a special cardiac rehab program can help older adults who recently had a heart event improve their balance and reduce their risk of falling. It's designed for people age 65 and older who are now stable enough to begin rehab.
Rome, RMAges 65 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT04576130Recruiting
ICD study after cardiac arrest from an abnormal heart rhythm
This study looks at an implantable defibrillator (ICD) strategy in people who survived a cardiac arrest caused by an abnormal rhythm (ventricular fibrillation or ventricular tachycardia). It aims to reduce the risk of another dangerous rhythm after the blocked heart arteries are fully treated.
CopenhagenAges 18 years+ - NCT07799363Recruiting
Heart imaging test comparison for patients getting a new heart valve
This study compares two heart imaging scans to see if a newer CT scan works as well as an MRI for checking blood flow and heart tissue in people having a heart valve replacement. It may help improve care for patients with aortic stenosis.
Huddinge, Stockholm CountyAges 60 years+ - NCT07482943RecruitingPhase 4
Dapagliflozin for heart function after Fontan procedure
This trial tests whether dapagliflozin, a diabetes drug that also helps the heart, can improve exercise ability and heart function in people who have had the Fontan procedure for a single ventricle heart defect.
Hong KongAges 12 years+ - NCT07016477Recruiting
Heart CT study for TAVI planning
This study is a registry (a collection of information) for people who are about to have a TAVI heart valve procedure. It will see how a new type of CT scanner (the NAEOTOM Alpha) can help doctors plan the procedure better.
Charleston, South CarolinaAges 18 years+ - NCT06410157Recruiting
Mindfulness for heart-brain health in adults 50-70
This study tests whether a daily mindfulness practice can help older adults improve how their heart and brain work together. You will do breathing exercises at home and come to USC twice for check-ups, including blood and urine tests and an MRI.
Los Angeles, CaliforniaAges 50–70 - NCT07159269Recruiting
Cardiac ultrasound training for emergency department providers
This study teaches nurse practitioners and physician assistants in the emergency department how to use a special type of heart ultrasound (called cardiac point-of-care ultrasound). The goal is to help these providers quickly and accurately check the heart at the bedside.
Durham, North CarolinaAges 18 years+ - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT07301489Recruiting
Heart study for lung screening participants
This trial adds a heart health check to an existing lung cancer screening study. It looks at old chest CT scans to assess heart disease risk and asks you to return for a follow-up visit one year later.
Lørenskog, AkershusAges 60–79 - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT04882488Recruiting
Testing heart scan measurements in severe aortic valve narrowing
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Bad Oeynhausen, North Rhine-WestphaliaAges 65 years+
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Common questions
- Are there clinical trials for cardiac disease?
- Yes. Clin2 currently lists 313 recruiting cardiac disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.