Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01390675Recruiting
Registry for heart valve replacement anesthesia during TAVR
This study tracks patients who get a transcatheter aortic valve implantation (TAVR), a procedure to replace a narrowed heart valve without open-heart surgery. It looks at the type of anesthesia used during the procedure and records outcomes to learn what works best for patients.
Munich, BavariaAges 18 years+ - NCT06969287RecruitingPhase 3
Testing fluvoxamine to prevent confusion after surgery
This trial tests if a medication called fluvoxamine can help prevent delirium (sudden confusion and disorientation) after non-cardiac surgery. If you are having surgery that requires at least a 2-day hospital stay, this study may be for you.
St Louis, MissouriAges 60 years+ - NCT06793670RecruitingPhase 4
Landiolol study for mitral valve surgery patients
This trial tests a short-acting beta-blocker called Landiolol given during mitral valve surgery to see if it helps the heart recover after surgery. It is for patients who have certain signs of heart strain before their operation.
Alessandria, PiedmontAges 18 years+ - NCT07063394Recruiting
Virtual reality to reduce opioid use after heart or lung surgery
This trial tests if using virtual reality after heart or chest surgery can help reduce the amount of strong painkillers (opioids) patients need. It may offer a non-drug way to manage pain and speed up recovery.
São Paulo, São PauloAges 16–40 - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT07017933Recruiting
Kidney support device for heart surgery patients
This trial tests a new device that helps support kidney function during heart surgery. It is for people with mild to moderate kidney problems who are having bypass or valve surgery.
Weston, FloridaAges 22–85 - NCT06961175Recruiting
Platelet function study in heart surgery
This study looks at how well platelets work during heart surgery using a special test called thromboelastography. It may help doctors understand and manage bleeding risks in people having planned heart surgery with a heart-lung machine.
SalamancaAges 18 years+ - NCT06486636Recruiting
Pericardiotomy in heart surgery
This trial tests whether opening the sac around the heart (pericardiotomy) during certain heart surgeries can help prevent future heart rhythm problems. It may be an option for people having surgery on the main artery from the heart, heart valves, or heart arteries.
New York, New YorkAges 18 years+ - NCT06294119Recruiting
Brain-heart-vessel interaction study in heart surgery patients
This study looks at how your brain, heart, and blood vessels work together during heart surgery. It uses simple tests to measure these connections, which may help doctors better understand your health.
San Donato Milanese, MilanAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT06968065Recruiting
Pain control after minimally invasive heart surgery: nerve block vs wound injection
This study compares two ways to manage pain after minimally invasive heart surgery: a nerve block injection near the ribs or injecting numbing medicine into the wound. The goal is to find which method works better for reducing pain and your need for painkillers.
IstanbulAges 18–75 - NCT07048002Recruiting
Silent brain infarct and cognitive decline after heart surgery
This trial tests a bundle of interventions to prevent silent brain infarctions (small 'silent' strokes) and thinking problems after heart or blood vessel surgery with a heart-lung machine. If you are 60 or older and having such surgery, this study may help protect your brain health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT06728826Recruiting
Preventing atrial fibrillation after heart surgery with pericardiotomy
This study tests if opening the sac around the heart (pericardiotomy) can lower the chance of developing an irregular heartbeat called atrial fibrillation after heart surgery. It is for people having surgery on the heart's valves, major blood vessels, or arteries.
ShanghaiAges 18 years+ - NCT07028593RecruitingPhase 4
Ciprofol for heart protection during lung surgery
This trial tests if a new sedative drug, Ciprofol, can reduce heart damage after non-cardiac surgery compared to standard care. It is for people aged 45–80 having planned lung surgery (like lobe removal or wedge resection) who will stay in the hospital for at least 3 days after the procedure.
WuhanAges 40–80 - NCT06279000RecruitingPhase 3
Colchicine for heart risk during major non-heart surgery
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Sankt Gallen, Canton of St. GallenAges 45 years+ - NCT07472959RecruitingPhase 4
Morphine for pain after heart bypass surgery
This study tests whether giving morphine during coronary artery bypass surgery can help control pain after the operation. It is for people having planned heart bypass surgery who are moderately sick and not already on strong pain medicines.
Istanbul, Outside of the USAges 18–80 - NCT07275307Recruiting
Test of a wound gel to prevent infections after heart surgery
This study tests whether a special gel applied to the chest incision during heart surgery can lower the chance of wound infections. The gel may help keep the incision site clean and help it heal better.
San Donato Milanese, MichiganAges 18 years+ - NCT07267013RecruitingPhase 2
Testing clindamycin instead of vancomycin in aortic heart surgery
This study tests if clindamycin, a common antibiotic, works as well as vancomycin to prevent infections during heart surgery on the aorta (the main artery from the heart). Patients must be having planned morning surgery with the heart-lung machine and understand French.
Nantes, FranceAges 18 years+ - NCT05833828Recruiting
Testing blood-pressure hormone changes during bypass surgery
This study looks at how a blood-pressure hormone system (RAAS) changes during coronary artery bypass surgery. It may help researchers understand better how to manage blood pressure and heart stress around the time of surgery.
BerlinAges 18 years+ - NCT07810621Recruiting
Low cardiac output after heart surgery
This study looks at how well the heart pumps right after bypass surgery and whether a special monitor can help predict problems. It may help doctors support patients better after surgery.
Ankara, AnkaraAges 18 years+ - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07286227Recruiting
Checking heart function before removing support tubes in heart surgery
This study compares two methods—visual checks and a special ultrasound of the heart—to see which better predicts how well the heart will pump after bypass machine support is removed during elective heart surgery.
ErzurumAges 18–75 - NCT05664308Recruiting
Watch-based heart rhythm monitoring after heart surgery
This study tests whether a connected watch can help monitor an irregular heart rhythm (atrial fibrillation) after heart surgery. It looks at people who develop new atrial fibrillation after surgery and compares how well monitoring works over the next 12 months.
Nantes, Loire AtlantiqueAges 18 years+ - NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70
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Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 295 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.