Clinical trials
Non-cardiac Surgery clinical trials
Below are recruiting non-cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT07839728Enrolling by invitation
How common is low body temperature after surgery in recovery?
This study looks at how common low body temperature (hypothermia) is after surgery in recovery rooms. It aims to help improve patient care by measuring temperature changes and related outcomes.
Madrid, MadridAges 18 years+ - NCT05812248Recruiting
Tracking heart and blood vessel events after major non-heart surgery
This study follows people after major surgery to see what predicts heart and blood vessel problems later. It does not test a new drug; it mainly collects health information to help clinicians reduce risk.
Guangzhou, GuangdongAges 45 years+ - NCT07746505Recruiting
Remimazolam vs midazolam for anesthesia in older adults
This study compares two sedative medicines used to start general anesthesia in patients 65 and older having non-cardiac surgery. The goal is to see which one is safer and works better for older patients.
HangzhouAges 65 years+ - NCT07713121Recruiting
Keeping blood pressure up during surgery to prevent confusion in older adults
This trial tests whether keeping blood pressure at 85 mmHg or higher during surgery can reduce confusion (delirium) after surgery. It is for older adults with high blood pressure who are having non-cardiac surgery.
HamburgAges 65 years+ - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT07634666Recruiting
Heart Safety Monitoring During Urologic Cancer Surgery
This study tracks heart health before and after major surgery for prostate or kidney cancer in older adults. Researchers want to predict which patients might experience heart problems after surgery so they can provide better care.
SeoulAges 60 years+ - NCT06399536Recruiting
Individualized blood management for major non-cardiac surgery
This trial tests a personalized approach to managing your own blood during surgery, which may reduce the need for donor blood transfusions. It is for people having planned non-cardiac surgery expected to need a large amount of blood.
Chengdu, SichuanAges 18–75 - NCT05778981Recruiting
Study of blood-vessel health during non-heart surgery
This study looks at how blood-vessel function changes around the time of non-heart surgery, especially in people 45 and older. It may help doctors better understand risks and recovery related to blood-vessel stress during hospitalization.
Independencia, Santiago MetropolitanAges 45 years+ - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT07385092Recruiting
Continuous monitoring after non-cardiac surgery
This trial compares continuous vital sign monitoring with standard spot checks for patients recovering from non-cardiac surgery. It aims to see if constant monitoring can improve safety and outcomes.
Hamburg, Free and Hanseatic City of HamburgAges 45 years+ - NCT07351149Recruiting
Study on kidney injury after major surgery in children
This trial looks at how often children develop kidney problems after major surgery that isn't on the heart or kidneys. The goal is to learn more about these injuries and how to prevent them.
Perth, Western AustraliaAges birth–16 years - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT06291714Recruiting
Non-invasive blood pressure prediction during major surgery
This trial tests a new, non-invasive way to predict drops in blood pressure during major hip, knee, pelvis, or spine surgery. The goal is to help doctors prevent low blood pressure, which can lead to complications.
GiessenAges 45 years+ - NCT07208500Recruiting
Arm cuff treatment before surgery to protect lungs in older adults
This study tests if a simple, non-invasive treatment (briefly inflating a blood pressure cuff on your arm) before surgery can reduce lung complications in older adults having non-heart, non-lung surgery. It may help protect your lungs during and after the operation.
ShanghaiAges 65 years+ - NCT06279000RecruitingPhase 3
Colchicine for heart risk during major non-heart surgery
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Sankt Gallen, Canton of St. GallenAges 45 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80 - NCT07168421RecruitingPhase 4
Landiolol to prevent fast heart rate during major surgery
This trial tests a short-acting medicine called landiolol to see if it can prevent dangerously fast heart rates during and after major surgery. It is for people who have heart risks and are having a planned non-cardiac surgery.
BernAges 45 years+ - NCT05481723RecruitingPhase 3
Lung ultrasound to guide fluid and blood pressure during surgery
This Phase 3 study tests whether using a lung ultrasound scan during surgery can better guide blood pressure and fluid needs. It may help stabilize patients during long operations and reduce complications related to poor circulation or fluid balance.
AmiensAges 18 years+ - NCT07030166Recruiting
Predicting kidney injury risk after non-cardiac surgery
This trial uses machine learning to predict the risk of acute kidney injury (AKI) after non-cardiac surgery. If you are 18 or older and having this type of surgery, it may help understand your risk and guide care.
NanjingAges 18 years+ - NCT07028593RecruitingPhase 4
Ciprofol for heart protection during lung surgery
This trial tests if a new sedative drug, Ciprofol, can reduce heart damage after non-cardiac surgery compared to standard care. It is for people aged 45–80 having planned lung surgery (like lobe removal or wedge resection) who will stay in the hospital for at least 3 days after the procedure.
WuhanAges 40–80 - NCT06969287RecruitingPhase 3
Testing fluvoxamine to prevent confusion after surgery
This trial tests if a medication called fluvoxamine can help prevent delirium (sudden confusion and disorientation) after non-cardiac surgery. If you are having surgery that requires at least a 2-day hospital stay, this study may be for you.
St Louis, MissouriAges 60 years+ - NCT06952387Recruiting
Personalized blood pressure for high-risk surgery patients
This study tests whether personalized blood pressure management during and after major surgery can reduce complications and death in older adults with heart or blood vessel risks. It aims to find the safest blood pressure targets for each patient.
Guangzhou, GuangdongAges 65–90
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Common questions
- Are there clinical trials for non-cardiac surgery?
- Yes. Clin2 currently lists 39 recruiting non-cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a non-cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a non-cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.