Clinical trials
Non-cardiac Surgery clinical trials
Below are recruiting non-cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 40 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT06324461RecruitingPhase 4
GLP-1 drug to protect heart after non-emergency surgery
This study tests whether a GLP-1 receptor agonist (a medication used for diabetes and weight loss) can reduce heart damage during or after planned non-cardiac surgery. It may help patients with heart risk undergoing intermediate to high-risk procedures.
Hong Kong, Hong Kong SARAges 18 years+ - NCT05812248Recruiting
Tracking heart and blood vessel events after major non-heart surgery
This study follows people after major surgery to see what predicts heart and blood vessel problems later. It does not test a new drug; it mainly collects health information to help clinicians reduce risk.
Guangzhou, GuangdongAges 45 years+ - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80 - NCT07208500Recruiting
Arm cuff treatment before surgery to protect lungs in older adults
This study tests if a simple, non-invasive treatment (briefly inflating a blood pressure cuff on your arm) before surgery can reduce lung complications in older adults having non-heart, non-lung surgery. It may help protect your lungs during and after the operation.
ShanghaiAges 65 years+ - NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT06399536Recruiting
Individualized blood management for major non-cardiac surgery
This trial tests a personalized approach to managing your own blood during surgery, which may reduce the need for donor blood transfusions. It is for people having planned non-cardiac surgery expected to need a large amount of blood.
Chengdu, SichuanAges 18–75 - NCT05481723RecruitingPhase 3
Lung ultrasound to guide fluid and blood pressure during surgery
This Phase 3 study tests whether using a lung ultrasound scan during surgery can better guide blood pressure and fluid needs. It may help stabilize patients during long operations and reduce complications related to poor circulation or fluid balance.
AmiensAges 18 years+ - NCT07746505Recruiting
Remimazolam vs midazolam for anesthesia in older adults
This study compares two sedative medicines used to start general anesthesia in patients 65 and older having non-cardiac surgery. The goal is to see which one is safer and works better for older patients.
HangzhouAges 65 years+ - NCT07634666Recruiting
Heart Safety Monitoring During Urologic Cancer Surgery
This study tracks heart health before and after major surgery for prostate or kidney cancer in older adults. Researchers want to predict which patients might experience heart problems after surgery so they can provide better care.
SeoulAges 60 years+ - NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults
This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.
New Delhi, National Capital Territory of DelhiAges 65 years+ - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT05732714Recruiting
Reduce heart event risk after major non-heart surgery
This study looks at ways to lower the chance of heart-related problems after major surgery that is not directly related to the heart. It focuses on people at higher heart risk who are expected to stay in the hospital for at least two days after surgery.
Toronto, OntarioAges 45–75 - NCT05778981Recruiting
Study of blood-vessel health during non-heart surgery
This study looks at how blood-vessel function changes around the time of non-heart surgery, especially in people 45 and older. It may help doctors better understand risks and recovery related to blood-vessel stress during hospitalization.
Independencia, Santiago MetropolitanAges 45 years+ - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06279000RecruitingPhase 3
Colchicine for heart risk during major non-heart surgery
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Sankt Gallen, Canton of St. GallenAges 45 years+ - NCT06291714Recruiting
Non-invasive blood pressure prediction during major surgery
This trial tests a new, non-invasive way to predict drops in blood pressure during major hip, knee, pelvis, or spine surgery. The goal is to help doctors prevent low blood pressure, which can lead to complications.
GiessenAges 45 years+ - NCT06343259Recruiting
Comparing anesthesia types for hip surgery in older adults
This study compares general anesthesia (you are completely asleep) versus spinal anesthesia (you are awake but numb from the waist down) during hip surgery to see which one is better at preventing heart muscle damage. It is for people 65 and older who are at moderate to high risk for heart problems.
IstanbulAges 65 years+ - NCT06510140Recruiting
Brain monitoring and frailty to predict confusion after surgery in older adults
This study tests if monitoring your brain waves during surgery and checking your frailty level can help predict whether you might become confused after surgery. It aims to improve care for older adults having major non-cardiac operations.
Saint-EtienneAges 75 years+ - NCT06225453Recruiting
Personalized blood pressure care during surgery
This study compares a personalized approach to managing blood pressure during surgery with the usual one-size-fits-all method. It looks at older adults or those with certain heart or blood vessel conditions having non-emergency surgery to see if individual targets can improve recovery.
SeongnamAges 45 years+ - NCT06788743Recruiting
Sevoflurane vs. propofol for preventing confusion after surgery in older diabetics
This trial compares two common anesthesia drugs (sevoflurane gas vs. propofol injection) to see which one lowers the risk of confusion or delirium after surgery in older adults with diabetes. It aims to find a safer way to give anesthesia for your operation.
Xi’an, ShanxiAges 60 years+ - NCT06802224RecruitingPhase 4
Medication to prevent kidney injury after major surgery
This study compares two medications given during surgery to see which one better protects the kidneys after the procedure. If you are having major non-cardiac surgery that lasts at least 2 hours and you need medication to support your blood pressure, this trial may be a good fit.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for non-cardiac surgery?
- Yes. Clin2 currently lists 40 recruiting non-cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a non-cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a non-cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.