Clinical trials
Cardiovascular Disease Risk clinical trials
Below are recruiting cardiovascular disease risk clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06517537Recruiting
Modified aortic root enlargement for small aortic valves
This trial tests a modified surgical technique for replacing a narrowed aortic valve in people whose valve opening is unusually small. The goal is to help the new valve fit better and work well.
Beijing, Beijing MunicipalityAges 50–70 - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT07704164RecruitingPhase 2
Colchicine to lower heart artery swelling in HIV
This trial tests if colchicine, a medicine for inflammation, can reduce swelling in the heart arteries of people with HIV. It may help lower the risk of heart problems in those already on a statin or similar medication.
BarcelonaAges 50 years+ - NCT07614958RecruitingPhase 3
Testing a new cholesterol medicine against bempedoic acid
This study compares two new medicines—obicetrapib and bempedoic acid—to see which one better lowers cholesterol in people whose cholesterol remains high despite taking standard medications. If your cholesterol isn't controlled well enough with current drugs, this trial may help you access an experimental treatment.
Stockton-on-TeesAges 18 years+ - NCT07583940Recruiting
Energy Intake and Blood Pressure in College Athletes
This study looks at whether not eating enough calories affects blood pressure in Division I college athletes. Researchers want to understand if improving nutrition can help prevent high blood pressure in young athletes.
Greensboro, North CarolinaAges 18–26 - NCT07550777Recruiting
Heart Health and Eye Injections Study
This study looks at how repeated eye injections of a drug called bevacizumab affect chemicals in your blood that relate to heart health and inflammation. Researchers want to understand if these eye injections might impact your cardiovascular risk.
Erzurum, ErzurumAges 50–80 - NCT07532863Recruiting
Heart Health Study for Newly Diagnosed Type 2 Diabetes
This study looks at how newly diagnosed type 2 diabetes affects heart and blood vessel health. Researchers will follow patients over time to understand the relationship between diabetes and cardiovascular risk.
Tangerang, BantenAges 40–70 - NCT07478887Recruiting
Corrie Lipids app for better cholesterol management
This study tests a smartphone app called Corrie Lipids to help people with high cholesterol get their LDL levels under control. It may be a good fit if you have high cholesterol that isn't well managed and you have heart disease risk factors like diabetes or a family history.
Baltimore, MarylandAges 18 years+ - NCT06784557RecruitingPhase 4
Study of ezetimibe's effect on gut bacteria
This trial tests whether ezetimibe, a cholesterol-lowering drug, changes the bacteria in your gut. It may help people with heart disease or high cholesterol who are already on a statin.
SeoulAges 19–80 - NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT05739253Recruiting
Study how the aorta changes after a valve procedure
This trial looks at how the ascending aorta (the main artery near the heart) changes over time after transcatheter aortic valve replacement. It may help doctors predict who is at risk of aorta enlargement after this less-invasive valve procedure.
Beijing, Beijing MunicipalityAges Any age - NCT07373938Recruiting
Carotid Artery Texture and Heart Risk in Type 2 Diabetes
This study uses a neck ultrasound to look at the texture of your carotid artery (a main blood vessel in your neck) to find early signs of heart and blood vessel risk. It is for adults with type 2 diabetes who have not already had a heart attack or stroke.
Elche, AlicanteAges 40–69 - NCT07370727Recruiting
Weight training for kidney transplant patients
This trial studies whether a personalized weight training program helps kidney transplant recipients improve their strength and health. It is for people who are at least one year post-transplant and have stable kidney function.
Bogotá, Bogota D.C.Ages 18–50 - NCT07360899Recruiting
Closing the left atrial appendage during heart surgery to prevent stroke
This trial tests if closing the left atrial appendage with a special stitch during planned heart surgery can help prevent strokes in people with atrial fibrillation. If you already need heart surgery, this extra step may reduce your future stroke risk.
Kamenitz, VojvodinaAges 18 years+ - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT06884631Recruiting
Heart failure risk assessment with exercise test and kidney health
This study uses a special exercise test, along with heart and kidney measurements, to better predict risks for people with heart failure. It may help your doctors understand your condition and choose the best care for you.
Milan, ItalyAges 18 years+ - NCT07272499RecruitingPhase 2
New drug combo for untreated high-risk mantle cell lymphoma
This trial tests a combination of three drugs (orelabrutinib, lisaftoclax, and rituximab) for people with mantle cell lymphoma who have not had treatment before and have high-risk features. The goal is to see if this combination works better than standard treatments.
Shanghai, Shanghai MunicipalityAges 14 years+ - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT05960604Recruiting
Monitoring blood pressure during surgery to predict low blood pressure
This study tests special ways of analyzing blood-pressure recordings during major surgery to better understand why some people develop low blood pressure (hypotension). If you have high blood pressure and need invasive blood-pressure monitoring, your surgery team will use readings to study patterns that may help predict or prevent low blood pressure.
AnkaraAges 18 years+ - NCT07211282Recruiting
Activity tracking for late-stage cardiac rehab
This trial uses a smartphone app to monitor and guide your physical activity during the final phase of cardiac rehab. It aims to help you safely stay active and improve your recovery.
Edegem, AntwerpAges 18 years+ - NCT06627322Recruiting
Diabetes type 2 trial for people with heart risks
This study compares different diabetes medicines to see which works best for people with type 2 diabetes who also have heart or blood vessel risks. It aims to find better treatment to protect your heart and kidneys.
DaeguAges 19 years+ - NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for cardiovascular disease risk?
- Yes. Clin2 currently lists 366 recruiting cardiovascular disease risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.