Clinical trials
Cardiovascular Disease Risk clinical trials
Below are recruiting cardiovascular disease risk clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07131605Recruiting
How weight-loss surgery affects heart health and inflammation
This study looks at how weight-loss surgery affects heart health by checking markers of inflammation in the blood and how blood vessels work. It may help understand why surgery lowers heart risk for people with obesity.
Cotignola, RavennaAges 18 years+ - NCT07113223Recruiting
AI heart test for heart failure detection in people over 65
This trial uses an artificial intelligence system to analyze electrocardiograms (ECGs, which are recordings of your heart's electrical activity) to detect heart failure early. It is for people over 65 who either have symptoms that might be heart failure or have risk factors for heart failure but no current symptoms.
MadridAges 65 years+ - NCT07094919Recruiting
Corheart 6 heart pump long-term study
This study follows people who have already received the Corheart 6 heart pump to see how well it works over time. You may qualify if you have severe heart failure that doesn't improve with standard treatments and you got the pump after October 1, 2021.
Shenzhen, GuangdongAges 18 years+ - NCT07079358Recruiting
Helping veterans get cardiac rehab after a heart event
This study tests ways to increase the number of veterans who attend cardiac rehabilitation (a program of exercise and education for heart health) after a heart attack, stent procedure, valve surgery, bypass surgery, or heart failure. The goal is to make it easier for veterans to get the care they need.
Gainesville, FloridaAges 18 years+ - NCT07078344RecruitingPhase 2
Omega-3 study for healthy African American and European American adults
This study tests whether taking omega-3 supplements can improve health and reduce diet-related differences between African American and European American adults. You would take daily capsules and visit the clinic regularly for about 6 months.
Tucson, ArizonaAges 18–64 - NCT07024706RecruitingPhase 2
Study of acalabrutinib plus venetoclax for relapsed CLL
This trial tests a combination of two targeted drugs for people with CLL or SLL whose cancer returned after first treatment with a similar type of therapy. The goal is to see if this approach works well with a fixed treatment duration.
Boston, MassachusettsAges 18–130 - NCT07030920RecruitingPhase 2
Reducing inflammation in people living with HIV
This trial tests if a drug can lower inflammation in people with HIV who are on effective treatment. It may help reduce the risk of heart disease and other problems related to chronic inflammation.
Montreal, QuebecAges 18 years+ - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06961630RecruitingEarly Phase 1
Heart protection after surgery
This trial tests if a personalized approach with blood thinners and statins can reduce heart risks after non-cardiac surgery. It is for adults 45 and older who had a heart injury during or after surgery.
New York, New YorkAges 45 years+ - NCT06931470Recruiting
Remote exercise training study for heart health
This study tests whether a remotely supervised exercise program is feasible and helpful for people who are at risk for heart disease but are not currently active enough. You would do exercises at home while being guided and monitored online.
New York, New YorkAges 45 years+ - NCT06907862Recruiting
SWITCH trial: swapping processed soy foods in a heart-healthy diet
This study tests whether swapping highly processed soy foods for less processed soy foods, as part of a heart-healthy diet, can improve blood pressure, blood sugar, and weight in adults with obesity and high blood pressure. It may be a good option if you have type 2 diabetes and are already on stable medications.
Toronto, OntarioAges 18 years+ - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Birmingham, AlabamaAges 12 years+ - NCT06842225Recruiting
How fitness and body fat affect blood sugar and blood vessels after inactivity
This study looks at how your fitness level and body fat affect blood sugar and blood vessel health when you are less active than usual. You'll be asked to ride an electric scooter to reduce your activity, so we can learn how your body responds.
Oxford, OhioAges 18–40 - NCT04686253Recruiting
Study how a heart opening and its flow link to stroke
This study looks at the detailed flow pattern through a patent foramen ovale (PFO)—a small opening in the heart—and how it may relate to stroke, TIA, or migraine. Doctors use special ultrasound testing with contrast to better understand who is most affected.
Beijing, Beijing MunicipalityAges 16–65 - NCT06784895Recruiting
Women-only cardiac rehab program
This trial tests a cardiac rehab program designed just for women. It aims to see if a women-only setting helps with recovery after heart problems or procedures.
Ann Arbor, MichiganAges 40–80 - NCT06347276Recruiting
PFO closure and brain microemboli study
This trial looks at whether closing a small hole in the heart (PFO) can reduce tiny clots traveling to the brain. It includes people who have had a stroke or migraine, and also those without symptoms but with high-risk features.
Beijing, Beijing MunicipalityAges 18–65 - NCT06695221Recruiting
Kefir trial for better health in Edmonton adults
This study tests if drinking kefir, a fermented dairy drink, can improve health in adults who are overweight or have high blood sugar or type 2 diabetes. It looks at how kefir might help with weight, blood sugar, and overall wellness.
Edmonton, AlbertaAges 24–70 - NCT06676280RecruitingPhase 4
Aspirin and statin study for high coronary calcium
This trial tests whether a daily aspirin and a statin medicine can help prevent heart problems in people with high calcium buildup in their heart arteries. It is for people aged 40 to 75 who have a high coronary calcium score (300 or more) and at least one additional risk factor like diabetes or high blood pressure.
AnyangAges 40–75 - NCT04725617Recruiting
Smoking-quit program for people with HIV and sleep issues
This study tests a wellness-based smoking-cessation program (including the stop-smoking medicine varenicline) for people living with HIV who want to quit. It aims to help you reduce or stop smoking while monitoring safety, sleep, and mental health during the program.
Phoenix, ArizonaAges 18–75 - NCT06650488RecruitingPhase 4
Clopidogrel vs aspirin after staph bloodstream infection
This trial compares two blood-thinning medicines, clopidogrel and aspirin, to see which better prevents heart attacks and strokes in people who have had a staph infection in their blood. If you already take aspirin for heart or blood vessel problems, this study may help find the safest way to protect your heart.
St. John's, Newfoundland and LabradorAges 18 years+ - NCT06632379RecruitingPhase 4
Atorvastatin after pregnancy to lower heart risk
This trial tests if taking atorvastatin, a common cholesterol medication, after delivery can reduce future heart problems in women who had high blood pressure or preeclampsia during pregnancy. It lasts for 6 months and includes participants who are at least 20 years old.
Columbus, OhioAges 20–50 - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06554301RecruitingPhase 1
Empagliflozin for pulmonary arterial hypertension study
This study tests if the diabetes drug empagliflozin can help people with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. It aims to see if the drug improves symptoms and is safe for patients with moderate symptoms.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for cardiovascular disease risk?
- Yes. Clin2 currently lists 366 recruiting cardiovascular disease risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.