Clinical trials
Cardiovascular Disease Risk clinical trials
Below are recruiting cardiovascular disease risk clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07214571RecruitingPhase 2
Study of S-337395 for RSV in high-risk adults
This trial tests an experimental drug called S-337395 for adults with RSV who are not in the hospital but are at high risk for severe illness. It aims to see if the drug can help prevent symptoms from getting worse.
Los Angeles, CaliforniaAges 18 years+ - NCT06587204Recruiting
Digital study for heart health in Black and Hispanic adults
This study uses a smartphone app to help Black and non-White Hispanic adults with heart or blood sugar conditions. It aims to make research easier to join from home and understand why some groups don't participate.
Miami, FloridaAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07717411RecruitingPhase 3
Trontinemab for people at risk of Alzheimer's symptoms
This study tests an investigational drug, trontinemab, in people who are cognitively healthy but have a blood marker suggesting a high chance of developing Alzheimer's symptoms later. The goal is to see if the drug can delay or prevent memory loss.
Irvine, CaliforniaAges 55–80 - NCT07192016RecruitingPhase 4
MRI study of triple inhaler for COPD with breathlessness
This study uses a special MRI scan to see how well a single triple inhaler works for people with COPD who have moderate to severe shortness of breath or feel their health is not good. It compares two groups: those with a low risk of flare-ups and those with a high risk, to find out if the treatment helps both groups.
London, OntarioAges 50–85 - NCT06500078Recruiting
Intermittent Diet for Heart Health in Kids
This study tests whether a special diet pattern (eating less at certain times) can improve heart health and blood sugar in school-aged children. It's for children who are overweight or have early signs of diabetes or heart risks.
ShanghaiAges 7–18 - NCT06416488Recruiting
HIIT for heart health in school-age kids
This trial tests whether a high-intensity interval training (HIIT) program can improve heart health and reduce risk factors like high blood sugar, cholesterol, and blood pressure in school-age children. It's for children who have at least one of these problems and are not already doing intense exercise.
Shanghai, Shanghai MunicipalityAges 7–18 - NCT07151768Recruiting
Validating a risk score for lung disease patients with pulmonary hypertension
This study is testing whether a new risk score can better predict outcomes for people who have both chronic lung disease and pulmonary hypertension (high blood pressure in the lungs). If you qualify, the researchers will follow your health over time to see how well the score works.
Philadelphia, PennsylvaniaAges 18–99 - NCT07006506RecruitingPhase 2
Belumosudil to prevent graft-versus-host disease after transplant
This study tests whether a drug called belumosudil can help prevent graft-versus-host disease (GVHD) after a stem cell transplant. It is for people who have had a recent transplant and are at risk for GVHD.
Basking Ridge, New JerseyAges 18 years+ - NCT06698614Recruiting
Magnetic resonance imaging to study kidney disease
This study uses a special MRI scan to look at the kidneys in people with different kinds of kidney disease, including acute kidney injury, chronic kidney disease, vasculitis, and after a kidney transplant. The goal is to better understand these conditions.
EdinburghAges 18 years+ - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT05558605Recruiting
AI ultrasound guidance for heart risk management
This trial tests whether using an artificial-intelligence (AI) tool during a heart ultrasound can help guide care for people at risk for heart problems. You might benefit if you have symptoms with exercise or heart risk factors, but you do not already have known heart failure or major heart disease.
Alice Springs, Northern TerritoryAges 45 years+ - NCT06731257Recruiting
Early discharge after a heart attack with home monitoring
This trial tests if people with a mild heart attack can go home early (within 48 hours) and be monitored virtually instead of staying in the hospital. It aims to make recovery more comfortable while ensuring safety.
LeedsAges 18–99 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT06745687Recruiting
BCMA/CD3 antibody for high-risk smoldering myeloma
This trial tests a new medicine called a BCMA/CD3 bispecific antibody for people with a very early form of multiple myeloma called high-risk smoldering myeloma. The goal is to see if this treatment can stop the disease from getting worse.
TianjinAges 18–78 - NCT06940414Recruiting
Study of high potassium in kidney disease patients in community
This study looks at how common high potassium levels are in people with chronic kidney disease who are not on dialysis. It may help find who is at risk and how to prevent it.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06431425Recruiting
Online genetic counseling clinic for inherited heart conditions
This trial tests an online genetic counseling clinic for people with certain inherited heart muscle diseases and their family members. It aims to provide presymptomatic counseling (before symptoms appear) through video calls, making it easier to access care from home.
Utrecht, UtrechtAges 18–90 - NCT06930521Recruiting
Monitoring heart health during HER2 therapy for breast cancer
This study tracks how well the heart handles HER2-targeted therapy (like Herceptin) during the first year of treatment for early-stage breast cancer. It helps keep you safe by checking heart function closely.
Toronto, OntarioAges 18–79 - NCT06820970Recruiting
Combined therapy for heart artery blockages that weren't fully opened
This trial tests if combining a new heart procedure with a special type of therapy called mindfulness therapy can help prevent heart problems in people with coronary artery disease that could not be fully fixed with stents or surgery.
Zhengzhou, HenanAges 18 years+ - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT07514663Recruiting
Effects of Corn and Avocado Oils on Heart Health
This study compares how corn oil and avocado oil affect your cholesterol and heart health markers. You'll eat controlled meals containing one of these oils for 3 weeks at a time to see which might be better for your cardiovascular risk factors.
Addison, IllinoisAges 18–74 - NCT06536959RecruitingPhase 2
VA plus PD-1 inhibitor for relapsed AML and high-risk MDS
This trial tests a combination of two drugs—a chemotherapy-like agent called VA and a PD-1 inhibitor (which helps your immune system fight cancer)—for people with AML or high-risk MDS that has not responded to or returned after initial treatment. The goal is to see if this combination can work better than standard treatments alone.
Beijing, Beijing MunicipalityAges 18–70 - NCT06704321Recruiting
Effects of TOTUM-448 on liver fat and heart health
This trial tests a supplement called TOTUM-448 to see if it can reduce liver fat and improve heart health in people with a fatty liver condition (MASLD). If you have excess liver fat and are overweight, this study could help find new ways to manage your condition.
Québec, QuebecAges 18–75
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Common questions
- Are there clinical trials for cardiovascular disease risk?
- Yes. Clin2 currently lists 366 recruiting cardiovascular disease risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.