Clinical trials
Cardiovascular Disease Risk clinical trials
Below are recruiting cardiovascular disease risk clinical trials, each written for real people, not researchers. We’re tracking 360 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06369571Enrolling by invitationPhase 1/Phase 2
Improving heart health in adults with epilepsy on a modified Atkins diet
This study tests whether a statin medication (atorvastatin) can help lower cholesterol and improve heart health in adults with epilepsy who have been on a modified Atkins diet for a year or more. It may be a good fit if you have high cholesterol and are not already on a statin or have had heart problems.
Baltimore, MarylandAges 18 years+ - NCT04840030Enrolling by invitation
Preventing Memory and Thinking Decline With Multidomain Program
This study tests a multi-part program (not just one activity) to help slow down memory and thinking decline in older adults at higher risk. You would complete brief thinking tests and follow the study’s coaching/intervention schedule to see if it helps over time.
Donostia / San Sebastian, GipuzkoaAges 60–85 - NCT06693934Recruiting
Prevention program for young adults at risk of diabetes
This trial offers a prevention program for young adults aged 18 to 44 who have at least one risk factor for diabetes but do not already have diabetes. The program aims to help prevent or delay the onset of diabetes.
Hong KongAges 18–44 - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Little Rock, ArkansasAges 12 years+ - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT07320703Recruiting
Diagnosing breathlessness in primary care
This project tests whether a tool called "Breathlessness Diagnostics in a Box" helps doctors find the cause of breathlessness more quickly. If you have unexplained or ongoing trouble breathing, this study may help improve your care.
GroningenAges 18 years+ - NCT01372800Recruiting
Study blood adiponectin levels and stroke/heart risk
This study measures a blood marker called adiponectin and looks at how it relates to heart and stroke (cardiovascular and cerebrovascular) problems over time. It may help doctors understand who is at higher risk, especially in Chinese participants.
Xi'an, ShaanxiAges 18–85 - NCT05888467Recruiting
Exercise study for women at risk of pregnancy heart problems
This study looks at how physical activity affects the heart and blood-vessel health “profile” in women who have risk factors for a pregnancy condition (called GHD, related to preeclampsia risk). It may help researchers find safer or more helpful activity guidance before pregnancy.
Diepenbeek, LimburgAges 18–50 - NCT06409702RecruitingPhase 4
Treating high-risk multiple myeloma with MRD testing
This trial tests a treatment plan for people with newly diagnosed high-risk multiple myeloma. It uses a special test called minimal residual disease (MRD) detection to see how well the treatment is working and guide next steps.
Suzhou, JiangsuAges 18 years+ - NCT07053462RecruitingPhase 1/Phase 2
Gene-edited kidney transplant to lower rejection risk
This trial tests a specially edited donor kidney designed to reduce the chance of rejection, especially for people with high sensitivity to donor kidneys. If it works, it could make more kidneys available for those who have a hard time finding a match.
Beijing, ChangpingAges 16–85 - NCT06601153Recruiting
Heart health study using CT scans and blood samples
This study looks at blood samples and CT scans from people with stable coronary artery disease to find new ways to predict and prevent future heart problems. If you've had or are about to have a cardiac CT and have blood stored, you might be able to join.
Pisa, ItalyAges 40–75 - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Huntsville, AlabamaAges 40–80 - NCT06826534Recruiting
At-home heart rehab for teens with heart failure risk
This study tests if a home-based exercise program using a Fitbit can help teens who had chemotherapy improve their heart and lung fitness. You would exercise at home, track your activity, and have monthly virtual check-ins for 6 months.
Los Angeles, CaliforniaAges birth–21 years - NCT05349955Recruiting
Primary care diabetes guideline program for older adults
This trial tests whether a diabetes treatment plan (based on published guidelines) delivered by primary care doctors in the community is safe and helpful for older adults. It focuses on people with type 2 diabetes who also have kidney problems and/or higher heart and blood-vessel risk.
Suzhou, JaingsuAges 65 years+ - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06276374Recruiting
Dual antiplatelet therapy after carotid artery stenting for high bleeding risk
This trial tests if taking two blood thinners (dual antiplatelet therapy) after a carotid artery stenting procedure is safe and effective for patients who have a higher risk of bleeding. It focuses on people with significant blockages in the neck arteries who are also at increased risk for serious bleeding or brain bleeds.
SeoulAges 19 years+ - NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT07214571RecruitingPhase 2
Study of S-337395 for RSV in high-risk adults
This trial tests an experimental drug called S-337395 for adults with RSV who are not in the hospital but are at high risk for severe illness. It aims to see if the drug can help prevent symptoms from getting worse.
Los Angeles, CaliforniaAges 18 years+ - NCT05693857Recruiting
Understanding heart risk from test results and questionnaires
This study looks at how well questionnaires and cholesterol test results match a person’s future heart risk. It may help researchers improve how doctors spot who is at higher risk and who can benefit from prevention.
ShatinAges 40–90 - NCT06587204Recruiting
Digital study for heart health in Black and Hispanic adults
This study uses a smartphone app to help Black and non-White Hispanic adults with heart or blood sugar conditions. It aims to make research easier to join from home and understand why some groups don't participate.
Miami, FloridaAges 18 years+ - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07192016RecruitingPhase 4
MRI study of triple inhaler for COPD with breathlessness
This study uses a special MRI scan to see how well a single triple inhaler works for people with COPD who have moderate to severe shortness of breath or feel their health is not good. It compares two groups: those with a low risk of flare-ups and those with a high risk, to find out if the treatment helps both groups.
London, OntarioAges 50–85 - NCT06416488Recruiting
HIIT for heart health in school-age kids
This trial tests whether a high-intensity interval training (HIIT) program can improve heart health and reduce risk factors like high blood sugar, cholesterol, and blood pressure in school-age children. It's for children who have at least one of these problems and are not already doing intense exercise.
Shanghai, Shanghai MunicipalityAges 7–18
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Common questions
- Are there clinical trials for cardiovascular disease risk?
- Yes. Clin2 currently lists 360 recruiting cardiovascular disease risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.