Clinical trials · Maryland
Cardiovascular Diseases clinical trials in Maryland
We’re tracking 35 recruiting cardiovascular diseases studies with a site in Maryland — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Baltimore, MarylandAges 18 years+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Baltimore, MarylandAges 18 years+ - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Baltimore, MarylandAges 45–99 - NCT02543996Recruiting
Providing blood or tissue samples to study disease
This study collects and stores biological samples (like blood and cord blood) to help researchers understand what causes disease. You may be asked to provide samples during pregnancy, delivery, or from an affected person, depending on eligibility.
Bethesda, MarylandAges 1 month–100 years - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Baltimore, MarylandAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Baltimore, MarylandAges 18 years+ - NCT05169333Recruiting
Oxford study using non-invasive imaging to learn risk factors
This study looks at factors that can predict health risks and uses non-invasive imaging (no major procedures) to collect information. It may help researchers better understand who is at higher risk over time and why.
Bethesda, MarylandAges 18–99 - NCT03374215Recruiting
Study hormone causes of high blood pressure in Black adults
This study looks at the body’s hormone signals to understand what causes primary aldosteronism (a condition that can lead to high blood pressure). By comparing clinical results and lab data, researchers hope to improve how the condition is diagnosed and managed, especially in Black participants.
Bethesda, MarylandAges 7–70 - NCT07136012RecruitingPhase 3
Olpasiran trial to lower Lp(a) and prevent first heart attack or stroke
This trial tests if olpasiran can lower a type of cholesterol called Lp(a) to help prevent a first major heart attack, stroke, or other heart problems. It is for people at higher risk due to risk factors or early signs of artery disease, but who have not yet had a heart attack or stroke.
Baltimore, MarylandAges 50–105 - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Baltimore, MarylandAges 18–100 - NCT06552767Recruiting
Thrombosis and blood vessel inflammation study
This trial aims to learn more about blood clots, inflammation, and blood vessel problems. It may help researchers better understand these conditions and how they affect people.
Bethesda, MarylandAges 5–100 - NCT00001853Recruiting
Heart Disease Risk Factors in Black Adults
This study examines why Black men and women have different heart disease risk factors, focusing on weight, cholesterol levels, and diabetes risk. Researchers want to understand these differences to help prevent heart disease in Black communities.
Bethesda, MarylandAges 18–70 - NCT04927429Recruiting
MRI study to improve heart imaging
This trial helps develop and fine-tune MRI scans that look at the heart and blood vessels. It may help people with heart-related symptoms or conditions by improving how MRI images are created and interpreted.
Bethesda, MarylandAges 18–100 - NCT05971433Enrolling by invitation
Studying how body stress signals affect sleep and heart health
This study looks at how “stress signals” in the body after an injury may affect sleep and cardiovascular (heart and blood vessel) health. It may help researchers understand what contributes to recovery and how to improve outcomes for wounded service members.
Bethesda, MarylandAges 18 years+ - NCT01143454Recruiting
Study unusual heart conditions and related genetic traits
This study looks at people with unusual or rare heart problems, or people with a family history of these issues. Doctors and researchers may collect and study your blood or tissue (and possibly store samples) to learn what causes the condition and how it may affect the heart.
Bethesda, MarylandAges 1–100 - NCT01316783Enrolling by invitation
Genetics study of obesity, diabetes, and heart risk
This study looks at genetic differences in adults from African diaspora groups to better understand risks for obesity, type 2 diabetes, and heart disease. You may help scientists learn why these conditions are more common in certain communities.
Bethesda, MarylandAges 18–120 - NCT07613099RecruitingPhase 3
Testing a new PET scan to detect lung and heart scarring
This study tests a new imaging scan (called 18F-FAPI PET/CT) that may help detect scarring in the lungs, heart, or blood vessels. If you have a heart, lung, or blood vessel condition that could cause scarring, this scan might show damage earlier and help doctors plan better treatment.
Bethesda, MarylandAges 18–100 - NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Baltimore, MarylandAges 18 years+ - NCT07293260RecruitingPhase 3
Olpasiran heart scan study for high Lp(a) patients
This study tests if a medication called olpasiran can lower a type of fat in your blood called Lp(a), which is linked to heart problems. You take the medicine or a placebo and get a special heart scan to see changes in your arteries.
Bowie, MarylandAges 35–80 - NCT05440422RecruitingPhase 2
Anifrolumab for heart and blood vessel health in lupus
This trial tests whether a drug called anifrolumab can improve early signs of heart and blood vessel damage in people with lupus. It may help prevent future heart problems and strokes.
Bethesda, MarylandAges 18–80 - NCT03372733RecruitingPhase 2
Omega-7 oil effects on blood fats and fullness
This study tests whether an omega-7 (palmitoleic acid–rich) oil changes your blood fat levels and how full you feel. It includes healthy adults and may help explain nutrition-based ways to support heart health.
Bethesda, MarylandAges 18–99 - NCT07517263RecruitingPhase 3
Long-term Safety Study of Pelacarsen Treatment
This study follows patients who completed an earlier pelacarsen trial to check if the treatment remains safe and well-tolerated over time. Pelacarsen is an experimental medicine being tested for heart and cholesterol health.
Baltimore, MarylandAges 18–100 - NCT04216342RecruitingPhase 1
Testing a new breathing-drug ingredient in healthy adults
This early study (Phase 1) tests how safe and tolerable Fx-5A is, and how the body processes it, in healthy volunteers. It’s mainly looking to understand side effects and drug levels rather than treating a disease.
Bethesda, MarylandAges 18–99 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Baltimore, MarylandAges 75 years+
Cardiovascular Diseases trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting cardiovascular diseases studies listed above.
- National Institutes of Health Clinical Center · 12 studies
- Johns Hopkins University · 5 studies
- Ascension Saint Agnes Heart Care · 4 studies
- Flourish Research · 3 studies
- Anderson Medical Research · 2 studies
- Centennial Medical Group · 2 studies
- Johns Hopkins Hospital · 2 studies
- MD Medical Research · 2 studies
What taking part in a cardiovascular diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cardiovascular Diseases trials in other states
Common questions
- Are there cardiovascular diseases clinical trials in Maryland?
- Yes. We're currently tracking 35 recruiting cardiovascular diseases studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cardiovascular diseases study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cardiovascular diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cardiovascular diseases studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.