Clinical trials
Chemotherapy clinical trials
Below are recruiting chemotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,990 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04926467RecruitingPhase 2
Chemo plus anakinra for pancreatic cancer
This Phase 2 study tests whether adding anakinra (an immune signal blocker) to standard chemotherapy can improve outcomes for some people with pancreatic ductal adenocarcinoma. It’s mainly for adults with stage I–III disease who have enough organ function and are able to come in for treatment and follow-up.
Dallas, TexasAges 18 years+ - NCT05990426Recruiting
Alternate day fasting during chemo for gynecologic cancers
This trial tests whether alternating between a fasting day and a normal eating day can help people recovering from gynecologic cancer surgery while they receive chemotherapy. It aims to see if this eating pattern is safe and helpful during treatment.
Chicago, IllinoisAges 18 years+ - NCT06915168Recruiting
Nerve symptom decision aid for breast cancer patients
This study tests a decision aid tool that helps people with breast cancer and nerve-related side effects from chemotherapy (like numbness or tingling) make better choices about their treatment. If you're on your third round of taxane chemo and have these symptoms, this tool may help you talk with your doctor.
Ann Arbor, MichiganAges Any age - NCT01821456Recruiting
Study of immune-suppressed people in Cologne
This study follows people whose immune systems are weakened (immunosuppressed). Researchers want to better understand what happens in this group, and what risks or outcomes may occur.
Cologne, North Rhine-WestphaliaAges 1 year+ - NCT03125980RecruitingPhase 3
Chemo timing before vs after colon cancer surgery
This Phase 3 study compares two schedules of a colon cancer chemo combination: starting before surgery or starting after surgery. It aims to see which timing helps people live longer and lowers cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT03494296Recruiting
Low-dose decitabine plus COP for relapsed lymphoma
This trial studies whether a low-dose chemotherapy medicine (decitabine) combined with a COP chemotherapy regimen can help adults whose diffuse large B-cell lymphoma (DLBCL) has come back or did not respond to treatment. It may be an option if you have measurable disease and can meet key safety and health requirements.
Harbin, HeilongjiangAges 18 years+ - NCT03498326RecruitingPhase 2
Gemcitabine plus celecoxib after pancreatic surgery
This trial tests whether adding celecoxib to gemcitabine chemotherapy after complete (R0) pancreatic tumor removal can lower the chance the cancer comes back. It may help people who have had successful surgery but still need anti-cancer treatment.
Hangzhou, ZhejiangAges 18–90 - NCT03647072RecruitingPhase 3
Test drug to reduce stomach side effects during lymphoma chemotherapy
This Phase 3 trial studies whether a proton pump inhibitor (a stomach acid blocker) works better than histamine-blocking medicines when added to chemotherapy for DLBCL lymphoma. The goal is to improve how well chemotherapy is tolerated or how the treatment works.
CairoAges 18 years+ - NCT03671252RecruitingPhase 3
Chemotherapy before surgery for rectal cancer vs chemo with radiation
This Phase 3 trial compares two treatment plans given before rectal surgery. It tests whether stronger chemotherapy alone works better than chemotherapy pills plus long-term radiation to improve outcomes for locally advanced rectal cancer.
Guangzhou, GuangdongAges 18–75 - NCT03196414RecruitingPhase 1/Phase 2
CAR T cell therapy for relapsed myeloma with multiple targets
This trial tests an immune therapy made from T cells to attack multiple markers on multiple myeloma cells (including CD138 and BCMA). It may help people whose myeloma has come back or resisted treatment, when there are no curative options left.
Suzhou, JiangsuAges 18–75 - NCT03961373RecruitingPhase 3
Standard vs longer lymph node surgery after chemo for stomach cancer
This study compares two surgical approaches to remove lymph nodes after you’ve already had chemotherapy for stomach cancer. It aims to see whether removing lymph nodes in a more extended way improves outcomes without causing unacceptable side effects.
SienaAges 18–80 - NCT04063527RecruitingPhase 3
Stage I ovarian cancer treatment after surgery
This trial studies whether an additional treatment after surgery can help people with early-stage epithelial ovarian cancer live longer and stay well for more time. It is meant for patients who had a detailed staging operation and are able to start treatment within 8 weeks.
Nagakute-shi, Aichi-kenAges 20 years+ - NCT04136886RecruitingPhase 3
Chemo trial for return of advanced nasopharyngeal cancer
This Phase 3 study tests a chemotherapy plan for people whose nasopharyngeal cancer has come back locally (T3/T4). It aims to see if treatment given after return of cancer can help control the disease without spreading to distant organs.
Guangzhou, GuangdongAges 18–70 - NCT04157569Recruiting
Study blood DNA markers after chemotherapy in older acute leukemia
This trial checks a blood test called “ctDNA” (tiny pieces of leukemia DNA in blood) after chemotherapy. It may help doctors understand how well treatment is working in older adults with acute leukemia.
BeijingAges 60–100 - NCT04288999RecruitingPhase 3
Surgery plus chemo versus chemo-radiation then surgery for recurrent rectal cancer
This study compares two treatment plans for locally recurrent rectal cancer: (1) surgery plus chemo, or (2) chemo plus radiation first, then surgery, followed by chemo. It aims to see which approach works better in controlling the cancer and helping patients recover.
ChibaAges 20–80 - NCT04453904Recruiting
Testing best added chemo and radiation after stage III uterine cancer
This study compares different ways of giving radiation and chemotherapy after surgery for stage III endometrial (uterine) cancer. It aims to find which approach works best to reduce cancer risk and improve outcomes.
Beijing, Beijing MunicipalityAges Any age - NCT04453826RecruitingPhase 3
Test PD-1 plus chemo-radiation for high-risk nasopharyngeal cancer
This Phase 3 trial tests whether adding a PD-1 immunotherapy (given with chemotherapy and radiation, and also after) can improve outcomes for people with high-risk nasopharyngeal cancer. It may help by strengthening the immune system’s attack on the cancer alongside standard treatment.
Guangzhou, GuangdongAges 18–70 - NCT04522687Recruiting
Blood lymphocyte changes studied during radiation and chemotherapy for lung cancers
This study looks at how a type of white blood cell in your blood changes while you receive radiation and chemotherapy. The goal is to see whether these blood changes relate to treatment, especially in certain chest (thoracic) cancers.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02836158RecruitingPhase 2/Phase 3
Test drug plus spinal chemotherapy for older PCNSL
This trial studies whether adding R-IDARAM and medication delivered into the spinal fluid can improve treatment for primary central nervous system lymphoma (PCNSL) in newly diagnosed older adults. It may help by targeting lymphoma cells in the brain, covering membranes, and spinal fluid.
Beijing, Beijing MunicipalityAges 60–75 - NCT04453813RecruitingPhase 3
Immunotherapy with chemoradiation for recurring nasopharyngeal cancer
This phase 3 trial tests whether adding toripalimab (an immunotherapy medicine) to standard chemo-radiation works better for treating nasopharyngeal cancer that has come back and cannot be removed by surgery. It aims to improve control of the cancer after it returns.
Guangzhou, GuangdongAges 18–70 - NCT02657785RecruitingPhase 2/Phase 3
Treating newly diagnosed brain lymphoma with added medicines into CSF
This trial studies a treatment plan for people with newly diagnosed non-Hodgkin lymphoma that has spread to the brain and covering tissues (meninges). It combines medicines given through the bloodstream with immunotherapy placed into the fluid around the brain (CSF) to improve control of the lymphoma.
Beijing, Beijing MunicipalityAges 18–75 - NCT03591276RecruitingPhase 1/Phase 2
Doxorubicin plus pembrolizumab for hormone-resistant breast cancer
This Phase 1b/2 trial tests a combination of pegylated liposomal doxorubicin and pembrolizumab for breast cancer that no longer responds to hormone treatment. It aims to see how well the combination works and how safely it can be given to patients with advanced disease.
JerusalemAges 18 years+ - NCT03692429RecruitingPhase 1
Testing new immune cells plus chemo for advanced colon cancer
This Phase 1 study tests CYAD-101, an immune-cell treatment made from donor T-cells, given with standard chemotherapy. It is for people with colon or rectal cancer that has spread and has not responded to prior treatments.
Tampa, FloridaAges 18 years+ - NCT03356054RecruitingPhase 1/Phase 2
Test drug for CD30-positive lymphoma after first treatment fails
This early-phase study tests a lymphoma treatment in adults whose diffuse large B-cell lymphoma (DLBCL) is “CD30-positive” and who didn’t respond well to first-line chemotherapy (like R-CHOP) or had an early relapse. It aims to see if the treatment can shrink the lymphoma and is safe enough to move forward.
RotterdamAges 18 years+
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Common questions
- Are there clinical trials for chemotherapy?
- Yes. Clin2 currently lists 1,990 recruiting chemotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.