Clinical trials
Children, Only clinical trials
Below are recruiting children, only clinical trials, each written for real people, not researchers. We’re tracking 3,085 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT06201494Recruiting
Studying early symptoms of asthma in children
This study follows children and teens who are being checked for asthma for the first time. It aims to learn more about the early symptoms of asthma to improve diagnosis and treatment.
PragueAges 3–18 - NCT04121468RecruitingPhase 1/Phase 2
Metformin trial for vision nerve recovery in young people with MS
This study tests whether metformin can help “reset” damaged nerve cells in the brain and improve vision-related nerve problems in children and young adults with multiple sclerosis. Participants are assigned to metformin or a comparison treatment in a blinded (not everyone knows which) study.
Toronto, OntarioAges 10–25 - NCT04252989Recruiting
Atropine eye drops for slowing worsening nearsightedness in kids
This trial studies using low-dose atropine eye drops to help slow worsening nearsightedness (myopia) in children. It may help kids whose myopia is actively getting worse, depending on how consistently the drops are used.
Saint-EtienneAges Up to 18 years - NCT04391335Recruiting
Breathing tests to spot lung scarring after stem cell transplant
This study checks new ways to measure breathing in children who had a stem cell transplant to better detect a lung condition called bronchiolitis obliterans syndrome. If you join, you’ll do breathing and imaging tests, and researchers will look for patterns that may help with diagnosis.
Toronto, OntarioAges 6–18 - NCT04433650Recruiting
Picture-based support for children’s person-centered cancer care
This study tests whether picture-based support can help children with cancer (ages 5–17) and the adults caring for them communicate and feel supported during care. It also needs the child to understand a simple number rating scale.
GothenburgAges 5–17 - NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT04477460Recruiting
Testing thicker feeds for babies after unexplained brief events
This trial looks at whether using thicker baby feeds can improve health outcomes for infants who have had their first “brief resolved unexplained event” (a short episode with no clear cause). It may help babies who are being monitored after this first episode.
Boston, MassachusettsAges birth–1 year - NCT04478292RecruitingPhase 3
New treatment strategy for children with newly diagnosed liver cancer
This Phase 3 study tests a modified treatment plan for children newly diagnosed with hepatoblastoma, a type of liver cancer. It may help improve how well treatment works and how safely it can be given by using a structured approach.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT04504227Recruiting
Testing thickened feeds to improve safe swallowing
This study looks at how using thickened feeds may change swallowing safety and function in children who have swallowing problems (dysphagia) or who are at risk for a type of concerning breathing event. The goal is to see whether thicker liquids help protect the airway and improve swallow patterns.
Boston, MassachusettsAges Up to 21 years - NCT04532346RecruitingEarly Phase 1
Hydroxychloroquine for genetic lung disease in children
This early-phase trial studies whether hydroxychloroquine can help children with certain genetic causes of interstitial lung disease (lung scarring/inflammation). It is designed for kids who are currently stable and have not recently taken hydroxychloroquine.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT04538053RecruitingPhase 4
Simpler antibiotics for uncomplicated bone and joint infections in children
This trial looks at whether a simpler antibiotic plan can work for children with uncomplicated bone or joint infections that start in the community. It may help reduce the need for complicated treatment while still keeping the infection under control.
Kingswood, New South WalesAges 1–18 - NCT04573439Recruiting
Protein needs study for healthy active children
This study looks at how much protein children who are already in the “normal weight” range need to support an active lifestyle. It may help researchers fine-tune nutrition guidance for kids who are active and healthy.
Little Rock, ArkansasAges 8–10 - NCT04664569Recruiting
Study of treatments for bacterial meningitis in children
This study enrolls children and newborns with suspected or confirmed bacterial meningitis. The goal is to understand and improve care for serious infections that affect the lining around the brain.
CréteilAges 1 day–18 years - NCT04681339Recruiting
Antibiotics in hospitalized children with community pneumonia
This study looks at how antibiotics are prescribed for children who are hospitalized with community-acquired pneumonia. It may help doctors choose more appropriate antibiotic use for kids in the hospital.
Filderstadt, Baden-WurttembergAges 3 months–18 years - NCT04684368RecruitingPhase 2
New treatment study for children and young adults with NGGCT brain tumors
This Phase 2 study tests a new treatment approach for certain brain tumors called NGGCT in children and young adults. It may help improve outcomes by targeting tumors in specific brain locations and using tumor marker tests to guide care.
Birmingham, AlabamaAges 3–29 - NCT04709432Recruiting
Study of ECMO care for children in China
This study looks at children (ages 1 day to 18 years) in mainland China who were treated with ECMO during the past 10 years. It aims to understand how ECMO was used and how care outcomes may have differed for children.
Shanghai, Shanghai MunicipalityAges 1 day–18 years - NCT04726241RecruitingPhase 1/Phase 2
Testing blood and bone marrow samples in young leukemia patients
This trial looks at blood and bone marrow samples from children and teens whose leukemia has come back or is hard to treat. The goal is to better understand the disease and guide future options for these patients.
Birmingham, AlabamaAges Up to 22 years - NCT04773366RecruitingPhase 3
Newly diagnosed LCH children may receive cytarabine treatment
This Phase 3 trial tests a treatment plan that includes cytarabine for children newly diagnosed with LCH (a rare condition where abnormal immune-related cells form lesions). It may help control the disease while comparing outcomes with a cytarabine-based protocol.
ShanghaiAges 1 day–18 years - NCT04792606Recruiting
Study tracking long-term hip outcomes in non-walking children
This study follows children with cerebral palsy who cannot walk (severe type) and have hip displacement, to see how hip treatment affects long-term outcomes. You may be asked your child’s caregivers to complete a questionnaire so researchers can compare results over time.
Toronto, OntarioAges 2–19 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT04850456Recruiting
Gamma globulin treatment for critically ill children with inflammation surge
This trial studies whether giving “human gamma globulin” can improve outcomes in very sick children in the ICU who have a severe infection causing an extreme inflammation reaction (“inflammatory storm”). If you’re in the hospital ICU with this complication, the study may offer a targeted treatment strategy and careful monitoring.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT04901702RecruitingPhase 1/Phase 2
Onivyde plus talazoparib or temozolomide for resistant solid tumors
This trial tests whether adding Onivyde to either talazoparib or temozolomide can shrink or control hard-to-treat (refractory or recurring) cancers in children and young adults. It aims to find safer dosing first, then look at how well the treatment works—especially for Ewing sarcoma.
Palo Alto, CaliforniaAges 1–30 - NCT04923126RecruitingPhase 1/Phase 2
Mirdametinib for children with low-grade brain tumors
This Phase 1/2 study tests mirdametinib, a targeted medicine, in children and young adults with low-grade glioma (a slower-growing brain tumor). It aims to find the best dose and see how well the treatment works, especially for tumors with certain “MAPK pathway” changes.
Memphis, TennesseeAges 2–24
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Common questions
- Are there clinical trials for children, only?
- Yes. Clin2 currently lists 3,085 recruiting children, only studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, only trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, only trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.