Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 3,111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05402813Recruiting
Study of hearing loss in children with GJB2 or OTOF gene changes
This study follows children with hearing loss caused by changes in specific genes (GJB2 or OTOF). It helps researchers understand how hearing develops over time and how children may do with or without cochlear implants.
ParisAges Up to 16 years - NCT05407129Recruiting
Improve hospital safety by sharing your recent experience
This trial asks patients, families, caregivers, and hospital staff to report what happened during a recent hospital stay to help improve safety. Your feedback may help the hospital change processes that prevent problems for others.
Boston, MassachusettsAges Any age - NCT05408715Recruiting
Natural history study of growth in children with type II collagen disorders
This study follows children with certain inherited “type II collagen” conditions that cause short height, to better understand how growth changes over time. It does not test a new treatment; it mainly tracks health and growth so doctors can learn what to expect.
ParisAges Up to 12 years - NCT05413278Recruiting
Helps teens with inherited metabolism conditions move to adult care
This study tests a targeted approach to help teenagers with inherited metabolism conditions successfully transfer from children’s to adult healthcare. It may help families feel more confident and reduce problems during the handoff to adult services.
ViennaAges 14–25 - NCT05414903Recruiting
Reading support study for children with balance/hearing loss
This study looks at how children with vestibular (balance) and/or hearing loss learn to read. It may help researchers understand what reading supports work best for children who have trouble with balance and sound processing.
Omaha, NebraskaAges 7–18 - NCT05417958Recruiting
Tube-feeding formula thickness trial for stomach symptom relief
This trial studies whether changing how thick your tube-feeding formula is can improve stomach symptoms like nausea, bloating, feeling full too soon, and early fullness. It may help people who mostly receive nutrition through a feeding tube and have moderate upper-GI symptoms.
Boston, MassachusettsAges 1 year+ - NCT05419934Recruiting
EMDR therapy for young children with stress and anxiety
This study tests whether EMDR therapy (a structured way to help process distressing experiences) helps children ages 3 to 6 who have symptoms related to trauma, stress, or anxiety. You’d be randomly assigned to receive the study therapy or a comparison condition, and researchers would track outcomes.
NiceAges 3–6 - NCT05419960Recruiting
Hearing and balance testing for teens with osteogenesis imperfecta
This study checks how well the inner ear and balance system work in children and young adults with osteogenesis imperfecta (OI). The goal is to better understand hearing and balance issues that can affect daily life.
ParisAges 12–20 - NCT05422508RecruitingPhase 2
Second chickenpox shot for healthy kids after one prior vaccine
This study gives a second chickenpox vaccine dose to healthy children who were vaccinated once before. It mainly checks safety and measures the body’s immune response to see how well the second dose works.
AnsanAges 4–6 - NCT05423171Recruiting
Extra hand-focused therapy for children with cerebral palsy
This trial tests an intensive therapy program that trains both hands together to improve hand use in children with cerebral palsy. It may help your child with everyday hand and arm skills, but it also requires meeting certain health, eye, and recent-treatment limits.
QuébecAges 6–17 - NCT05427123Recruiting
Study for kids and teens with bipolar or cyclothymic disorder
This trial is testing treatments for children and teens (ages 9–19) who have been diagnosed with bipolar disorder or cyclothymic disorder. It also requires regular participation from a caregiver so the team can track symptoms and response over time.
Los Angeles, CaliforniaAges 9–19 - NCT05427136Recruiting
Study early lung problems after childhood cancer treatment
This study looks for early lung (breathing) problems in children after certain cancer treatments, using lung tests and sometimes MRI scans. It may help doctors spot breathing complications earlier and guide better care.
BaselAges 4–22 - NCT05434572Recruiting
Neuromuscular disease biobank for research samples
This trial is building a biobank (a secure research collection) from people with neuromuscular diseases, their families, or healthy volunteers. By joining, you help researchers study these conditions and improve future treatments.
Richmond, VirginiaAges Up to 75 years - NCT05442671Recruiting
Exercise coaching program for children with pulmonary hypertension
This trial tests whether a structured exercise program, done with remote support, is safe and helpful for children with pulmonary hypertension. It aims to improve how well kids function day-to-day while they stay on their usual PH medications.
Philadelphia, PennsylvaniaAges 8–18 - NCT05442515RecruitingPhase 1/Phase 2
CAR T-cell treatment for hard-to-treat B-cell cancers in youth
This trial tests a personalized immune-cell therapy (CAR T cells) made to attack B-cell cancers that have come back or did not respond to prior treatment. It aims to see how well the treatment works and how safe it is in children and young adults.
Bethesda, MarylandAges 3–39 - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Mobile, AlabamaAges 2 years+ - NCT05448807RecruitingPhase 3
Phentolamine to reverse numbing from dental local anesthesia in kids
This trial studies whether phentolamine can quickly undo (reverse) the numbness from local anesthesia used during dental procedures in children. It may help kids feel normally sooner and safely use their mouth (like speaking and drinking) after treatment.
Cairo, El ManialAges 5–7 - NCT05449756Recruiting
Long-term follow-up for children from the TEMPO study
This study checks on children who already took part in the TEMPO study during their first year of life. It helps researchers understand how things turned out over time and uses your child’s earlier study information.
BeekAges 3–10 - NCT05455359RecruitingPhase 4
Tube-fed children at high risk for aspiration pneumonia
This Phase 4 study looks at gastrointestinal movement (dysmotility) and how it may increase the risk of aspiration pneumonia in children who eat through a tube and have swallowing safety problems. It may help doctors better prevent lung infections in children who cough/choke and need suction often.
Boston, MassachusettsAges 5–21 - NCT05465174RecruitingPhase 2
Tovorafenib for children and young adults with craniopharyngioma
This trial studies tovorafenib to treat craniopharyngioma in children and young adults. It aims to shrink the tumor or slow its growth, and to learn which patients benefit most and what side effects to expect.
Birmingham, AlabamaAges 1–39 - NCT05468359RecruitingPhase 1/Phase 2
Testing four medicines in children and teens with hard-to-treat tumors
This early-phase trial studies how safe and effective a combination of four medicines is for children and teens with certain solid tumors that have come back or cannot be controlled with standard treatment. It may help by improving tumor control, while also carefully tracking side effects.
Germantown, TennesseeAges Up to 30 years - NCT05484128Recruiting
Probiotic for kids taking acid-reducing medicine
This trial studies whether a specific probiotic (Lactobacillus reuteri) is helpful for children who need acid-reducing medicine for reflux or stomach discomfort. It may help improve stomach symptoms while they are on or need treatment with proton pump inhibitors.
BariAges 1–14 - NCT05485155RecruitingPhase 2
Zemaira trial for adults with eosinophilic esophagus
This Phase 2 study tests Zemaira (an alpha-1 antitrypsin treatment given through an IV) to see if it improves eosinophilic esophagitis (EoE) in adults. You may be able to help researchers learn whether this treatment can reduce EoE activity when standard treatments haven’t worked.
Bethesda, MarylandAges 18–70 - NCT05488080Recruiting
Improving emergency care for children with appendicitis or fractures
This project looks at how emergency department care is delivered for children with possible appendicitis or a long bone fracture, with a focus on reducing inequities. You may be eligible if your child comes to the emergency department for symptoms that could fit these conditions, and they are not in the most immediately life-threatening category.
Washington D.C., District of ColumbiaAges birth+
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 3,111 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.