Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 2,992 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06627543Enrolling by invitation
Enzyme replacement therapy for heart health in Gaucher type 3
This study looks at how enzyme replacement therapy affects heart function in children with Gaucher disease type 3. It aims to see if the therapy helps keep the heart healthy.
AsyutAges Any age - NCT04596852Recruiting
Testing a new stiffness and spasticity measuring method in children
This study checks whether a special device can reliably measure muscle stiffness and spasticity (tight, overactive muscles) in children. It includes children with cerebral palsy and healthy children to compare measurements and improve accuracy.
Saint-Fargeau-PonthierryAges 7–18 - NCT04837105Recruiting
Game-based training to help children walk better with cerebral palsy
This study tests whether a serious video game can improve walking and movement in children with cerebral palsy. It may help your child practice safer, more effective walking skills through guided play.
Saint-Fargeau-Ponthierry, Île-de-France RegionAges 10–18 - NCT06616857Recruiting
Smartphone app to boost activity in teens with CF
This study tests a personalized smartphone app to help teens and young adults with cystic fibrosis be more active. The app provides tailored tips and support to encourage daily physical activity.
Jacksonville, FloridaAges 13–25 - NCT06607692RecruitingPhase 1/Phase 2
LuPARPed: Targeted radiation plus olaparib for certain childhood cancers
This trial tests a combination of a radioactive drug (Lutathera) and a targeted pill (olaparib) for children and teens whose solid tumors have come back or not responded to treatment and show high levels of a specific receptor (SSTR) on scans. The goal is to see if this two-drug approach can shrink tumors or stop them from growing.
Boadilla del Monte, MadridAges 3 years+ - NCT06614920Recruiting
Plant-based food prescription for food-insecure families
This study gives families who are struggling with food and money a free plant-based food prescription. It aims to see if healthy foods can improve health and reduce hunger.
Miami, FloridaAges Up to 99 years - NCT06609694Recruiting
Comparing oxygen delivery methods for children with sleep apnea
This study tests a new way to give oxygen to children aged 5-17 who have obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to see if a demand oxygen delivery system works better than standard care. This could help children with Down syndrome who often have untreated sleep apnea.
Cincinnati, OhioAges 5–17 - NCT06612645RecruitingPhase 1
CAR T cell therapy for children with solid tumors that returned
This trial tests a new type of immune therapy called CAR T cells designed to find and attack a protein called B7-H3 on solid tumor cells. It's for children and young adults whose cancer came back or didn't respond to standard treatment.
Bangkok, PathumwanAges 1–25 - NCT05691283Recruiting
Brain stimulation study for children with autism
This study tests whether a noninvasive brain stimulation technique (tDCS placed on the scalp) may help children and teens with autism. It will compare outcomes before and after the stimulation sessions to see if it is safe and potentially beneficial.
Dalls, TexasAges 5–21 - NCT06245239Recruiting
Measuring pain in young children after surgery
This study looks at whether a non-invasive tool called perfusion index can help doctors measure pain in children under 3 years old after hypospadias repair surgery. This could lead to better pain management for young children who cannot easily describe their pain.
Asyut, Assuit GovernorateAges 1 day–3 years - NCT06597006RecruitingPhase 3
Study of inclisiran for children with homozygous familial high cholesterol
This trial tests a new medicine called inclisiran to lower very high cholesterol in children aged 2 to 12 who have a specific genetic condition (homozygous familial hypercholesterolemia, or HoFH). You may not need to change your current cholesterol treatments, and the study will check if inclisiran can help reduce your LDL cholesterol further.
San Francisco, CaliforniaAges 2–11 - NCT06597019RecruitingPhase 3
Study of inclisiran for children with high cholesterol
This trial tests a medicine called inclisiran to lower high cholesterol in children ages 6 to 12 with a genetic condition called heterozygous familial hypercholesterolemia (HeFH). It may help children who still have high cholesterol despite taking other treatments.
San Francisco, CaliforniaAges 6–11 - NCT06594900Enrolling by invitation
Muscle strength in kids before puberty, with training
This study looks at how resistance training affects muscle function in prepubertal children. It compares changes from training to normal growth, and aims to help kids get stronger safely.
Basel, BasellandschaftAges 7–11 - NCT06589128Recruiting
Eye product for digital eye strain in children
This study tests an eye product to see if it helps relieve digital eye strain (sore, tired, or dry eyes from screens) in children. It is for kids who have mild to moderate symptoms from using digital devices.
Kepala Batas, Pulau PinangAges 10–11 - NCT06585631Recruiting
Collaborative care for young men with HIV and substance use
This study looks at how to better support young men living with or at risk for HIV while also addressing substance use. You'll work with a care team that helps you stay healthy and connected to services.
Baltimore, MarylandAges 15–29 - NCT06587529Recruiting
Preventing exploitation of teens in Des Moines
This program teaches teens how to recognize and avoid situations involving exploitation or trafficking. It may help you feel safer and more informed about these risks.
Des Moines, IowaAges 13–19 - NCT06583525Enrolling by invitation
Testing the TAC Program for teens with complex health needs
This study tests a program called TAC that helps teens with complex health needs move from SickKids to adult health care. It's for 16- to 18-year-olds who have multiple long-term conditions or a rare disease and might need extra support during this big change.
Toronto, OntarioAges 16–18 - NCT06593951Recruiting
EPM1 natural history study
This study will follow people with EPM1 over time to better understand the disease. It is a registry, meaning you will share information through video calls and questionnaires, with no experimental treatments involved.
Boston, MassachusettsAges Any age - NCT06578507RecruitingPhase 2
Twice-daily hydroxyurea liquid for children with sickle cell disease
This trial tests a new twice-daily liquid form of hydroxyurea (a common SCD medicine) in children ages 9 months to 11 years with sickle cell disease. It will check how the medicine works in the body, if it is safe, and if it helps reduce pain crises and other complications.
CréteilAges 9 months–11 years - NCT06582745RecruitingPhase 2
Trametinib for Langerhans cell histiocytosis (LCH)
This trial tests a targeted drug called trametinib (a MEK inhibitor) for people with Langerhans cell histiocytosis (LCH) that is newly diagnosed, relapsed, or hasn't responded to other treatments. It aims to see if trametinib can better control the disease with fewer side effects.
Fort Worth, TexasAges 1–30 - NCT06579469Recruiting
Study of later effects of CAR T cell therapy
This study follows children and young adults who received CAR T cell therapy to understand any long-term side effects that may appear months to years later. By joining, you help researchers learn how to better care for patients after this treatment.
Aurora, ColoradoAges Up to 30 years - NCT06570889RecruitingPhase 3
Vitamin D in pregnancy to prevent early childhood asthma
This trial tests if taking extra vitamin D during pregnancy can prevent asthma in young children. It is for pregnant women in Denmark who already have certain healthy fat levels in their blood.
Gentofte MunicipalityAges 18–45 - NCT06578416Recruiting
Stuttering development in young children
This study looks at how stuttering develops in young children by comparing kids who stutter with those who don't. It aims to understand the differences to help improve future treatments.
East Lansing, MichiganAges 3–6 - NCT06582225Recruiting
Online CBT for OCD in children with autism
This study tests if internet-based cognitive behavioral therapy (CBT) can help children and teens with autism who also have OCD. Treatment is delivered online with parent support, making it easier to access care at home.
Lund, Skåne CountyAges 7–17
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 2,992 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.