Clinical trials
Chronic Back Pain clinical trials
Below are recruiting chronic back pain clinical trials, each written for real people, not researchers. We’re tracking 331 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05968664Recruiting
Test whether new spinal cord stimulation settings improve chronic pain
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
Houston, TexasAges 22 years+ - NCT06590181Recruiting
Yoga Nidra with acceptance for chronic pain relief
This study tests a deep relaxation practice called Yoga Nidra, combined with mental imagery and acceptance, to see if it helps with long-lasting pain. You will take part in guided sessions from home via the internet.
Orlando, FloridaAges 18–75 - NCT07588490Recruiting
TENS for sudden severe lower back pain in the emergency room
This trial tests a pain-relief device called TENS (a small machine that sends mild electrical pulses through your skin) for people with sudden, severe lower back pain in the emergency department. Researchers want to see if TENS can help reduce your pain quickly without extra medications.
BrusselsAges 18 years+ - NCT06918535Recruiting
Relaxation vs muscle technique for neck pain in computer users
This study compares two therapies for neck pain in people who use computers for long hours. The goal is to see which method better reduces pain and stiffness from tight neck muscles.
Karachi, SindhAges 20–45 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT07030582Recruiting
Online therapy for back pain and recovery after spinal fusion
This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.
Nantong, JiangsuAges 18–55 - NCT06009263Recruiting
Exercises for chronic low back pain
This study compares two types of exercises to see which one better strengthens a key lower back muscle. It may help if you have ongoing back pain.
Giza, DokkiAges 25–55 - NCT05922007Recruiting
Study of chronic pain effects on daily life
This study looks at how long-lasting pain and its treatment affect quality of life and physical activity. It asks people to complete questionnaires to understand what changes over time.
Ostrava, Moravian-Silesian RegionAges 18–65 - NCT05706103Recruiting
Exercise therapy for recurrent low back pain with brain changes
This trial studies whether a specific exercise program can improve recurrent low back pain by changing activity in muscles and the brain. If you have non-specific low back pain that comes and goes over time, you may be asked to do exercises and undergo brain and muscle testing (including MRI).
Ghent, Oost-VlaanderenAges 18–45 - NCT06758414Recruiting
CBT for chronic pain in veterans with serious mental illness
This trial tests a type of talk therapy called Cognitive Behavioral Therapy for Chronic Pain, designed for veterans with serious mental illness. It aims to help you manage back pain and improve your quality of life.
Baltimore, MarylandAges 18 years+ - NCT07732062Recruiting
Emotion-focused therapy for chronic pain patients using medical cannabis
This study tests a new type of talking therapy (vEAET-H) to see if it helps people with chronic pain who are already using medical cannabis. The goal is to find out if adding this therapy can improve pain and well-being.
Tel AvivAges 18 years+ - NCT03852381Recruiting
Spinal cord stimulation for nerve pain after back surgery
This study looks at how spinal cord stimulation (a device that sends mild signals to the spinal cord) affects nerve pain after lumbar surgery. It also aims to help predict who is most likely to improve and why, comparing patients with and without certain sensory symptoms.
Toronto, OntarioAges 18–80 - NCT05507853Recruiting
Study of body pain sensitivity during pregnancy
This study looks at “central sensitization,” which means the nervous system may become more sensitive to pain, in pregnant people. It aims to understand pain changes during pregnancy and how different factors may affect them.
GothenburgAges 18 years+ - NCT07532070Recruiting
Exercise and Therapy for Chronic Pain and Sleep Problems
This study tests whether exercise, talk therapy for sleep problems, or both together can help people with long-term back, hip, or knee pain who also struggle with sleep. You'll attend video appointments and try one of these approaches for several weeks.
San Antonio, NevadaAges 18 years+ - NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55 - NCT07586397Recruiting
Hip Pain Treatment Study With Physical Activity Focus
This study tests a new approach to treating long-lasting hip pain that combines psychology and exercise. It's designed for people whose hip pain is affected by worry or stress, and who aren't as physically active as they'd like to be.
Boston, MassachusettsAges 18 years+ - NCT06361485RecruitingPhase 1
Umbilical cord injection for chronic low back pain
This study tests whether a special injection made from umbilical cord tissue is safe and can help with long-term low back pain. It is for adults who have not had recent back procedures or certain health problems.
Scottsdale, ArizonaAges 20 years+ - NCT06585033Recruiting
Spinal cord stimulation for pain after back surgery
This trial tests how much of the pain relief from spinal cord stimulation is due to the placebo effect. It is for people with ongoing leg pain after back surgery who have already tried other treatments without success.
ArnhemAges 18–70 - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT07049029Recruiting
Physical activity and pain resilience study for teens
This study tests if physical activity can help teenagers with chronic pain feel better and be more active. It may help you learn ways to manage pain.
Columbus, OhioAges 12–17 - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT05537662Recruiting
Testing a wearable system to reduce diabetic nerve back pain
This study tests an Abbott device that uses sensing and electrical stimulation to help reduce chronic back and/or leg pain. It also tracks pain changes and diabetic control using wearables and regular questionnaires to see if the system improves outcomes.
Chicago, IllinoisAges 18 years+ - NCT05776771Recruiting
Spine movement study for people with back or neck pain
This study measures how your spine and back/neck move using motion testing and equipment. It may help researchers better understand differences between people with spine pain and people without.
Columbus, OhioAges 18 years+
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Common questions
- Are there clinical trials for chronic back pain?
- Yes. Clin2 currently lists 331 recruiting chronic back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.