Clinical trials · Los Angeles, CA
Chronic Disease clinical trials in Los Angeles
We’re tracking 67 recruiting chronic disease studies with a site in or near Los Angeles — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Los Angeles
- NCT06878261RecruitingPhase 3
Tezepelumab for moderate to very severe COPD
This study tests a new medication called tezepelumab (given as a shot) to see if it can reduce COPD flare-ups in people with moderate to very severe COPD who have had recent flare-ups despite using inhalers. It may be an option for those with higher levels of eosinophils (a type of white blood cell) in their blood.
Los Angeles, CaliforniaAges 40–80 - NCT06585774RecruitingPhase 3
Axatilimab plus steroids for new chronic GVHD
This study tests a new drug called axatilimab combined with steroids as a first treatment for chronic graft-versus-host disease (GVHD) after a stem cell transplant. It aims to see if this combination helps control symptoms better than steroids alone.
Los Angeles, CaliforniaAges 12 years+ - NCT07116031RecruitingPhase 2
Belumosudil for children with chronic GVHD
This study tests a new medicine called belumosudil for children with chronic graft-versus-host disease (GVHD) that hasn't improved with at least 2 other treatments. The goal is to see if it can help control the disease and improve symptoms.
Los Angeles, CaliforniaAges 1–18 - NCT06619561RecruitingPhase 2
Testing vimseltinib for chronic graft versus host disease
This trial tests a new drug called vimseltinib for people with active chronic graft versus host disease (cGVHD) that hasn't gotten better after at least two prior treatments. The goal is to see if vimseltinib can help control the condition.
Los Angeles, CaliforniaAges 18 years+ - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Los Angeles, CaliforniaAges 40–80 - NCT07753993RecruitingPhase 3
Study of elecoglipron for chronic kidney disease
This trial tests an investigational medicine called elecoglipron for people with chronic kidney disease. It aims to see if it can improve kidney health compared to a placebo (inactive pill) and may be an option for those already on standard blood pressure and kidney protective medications.
Huntington Park, CaliforniaAges 18 years+ - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Glendale, CaliforniaAges 18–75 - NCT06283966RecruitingPhase 3
Triple inhaler for COPD with heart risk
This study tests a triple-combination inhaler (budesonide, glycopyrronium, and formoterol) to see if it can help protect the heart and lungs in people with COPD who also have heart problems or high risk for them.
Inglewood, CaliforniaAges 40–80 - NCT04684602RecruitingPhase 1/Phase 2
Study of stem cells for several short- and long-term illnesses
This early-stage study tests whether injections of mesenchymal stem cells can be safe and helpful for certain chronic (long-term) and acute (short-term) conditions. You might be considered if you can consent, are able to return for follow-up visits, and do not have key reasons that would make stem-cell treatment unsafe.
Culver City, CaliforniaAges 18 years+ - NCT07776210RecruitingPhase 3
Eye drops for chronic dry eye after stem cell transplant
This trial tests an eye drop solution for people with chronic dry eye caused by graft-versus-host disease after a stem cell transplant. It aims to see if the drops can reduce eye discomfort and improve the eye surface.
Beverly Hills, CaliforniaAges 18 years+ - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
West Los Angeles, CaliforniaAges 18 years+ - NCT04042844RecruitingPhase 2
Single injection treatment for chronic low back disc pain
This Phase 2 study tests whether one injection of BRTX 100 can reduce pain and improve function in people with chronic, disc-related low back pain. It looks for whether the treatment is safe and works better than what you’ve already tried.
Santa Monica, CaliforniaAges 18 years+ - NCT06970977Recruiting
Chronic sinusitis questionnaire validation study
This study is testing a new questionnaire to better understand chronic sinusitis symptoms. It may help improve how doctors diagnose and treat the condition.
Santa Monica, CaliforniaAges 18 years+ - NCT06883305RecruitingPhase 3
Testing tezepelumab for moderate to severe COPD
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
Torrance, CaliforniaAges 40–80 - NCT07091019Recruiting
CML patient experience study on standard TKI therapy
This study tracks the experiences and health outcomes of people with chronic myeloid leukemia (CML) who are taking approved first or second line tyrosine kinase inhibitor (TKI) medicines. It helps doctors learn how these treatments work in everyday care.
Torrance, CaliforniaAges 18–100 - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Torrance, CaliforniaAges Any age - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Torrance, CaliforniaAges 18 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
Torrance, CaliforniaAges 18–95 - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT07025538RecruitingPhase 1
Preventing chronic graft-versus-host disease with ruxolitinib
This trial tests whether the drug ruxolitinib, given based on a blood test that predicts risk, can prevent chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It may help people who have a higher risk of developing this complication.
Duarte, CaliforniaAges 18 years+ - NCT05996627RecruitingPhase 2
Belumosudil for early treatment of chronic graft-versus-host disease
This trial tests a pill called belumosudil to see if it can help people with chronic graft-versus-host disease (a common complication after a stem cell transplant where donor cells attack your body). It is for patients who have symptoms but are not yet on strong immune-suppressing drugs.
Duarte, CaliforniaAges 18 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Duarte, CaliforniaAges 18–66 - NCT07235501Recruiting
Understanding immune cells after stem cell transplant
This study looks at immune cells in your blood and in tissues affected by chronic graft-versus-host disease (a condition where donor cells attack your body) after a stem cell transplant. By analyzing samples, researchers hope to better understand this condition and improve future treatments.
Duarte, CaliforniaAges 7 years+ - NCT04160429Recruiting
Biospecimen testing to measure chemicals during treatment
This trial collects small samples like blood, sweat, and saliva while you’re taking certain medicines. Researchers will analyze these samples to see if they can detect chemical levels, which may help improve monitoring for people with chronic or infection-related illnesses.
Duarte, CaliforniaAges 18 years+
Hear when a new Chronic Disease trial opens near Los Angeles, CA
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Chronic Disease trials in other cities
Where these studies are running near Los Angeles
Institutions with a site for the recruiting chronic disease studies listed above.
- City of Hope · 7 studies
- Research Site · 5 studies
- Amicis Research Center - Valencia- Site Number : 8400119
- Beverly Hills Institute of Ophthalmology
- Beverly Hills Optometry
- Children's Hospital Los Angeles- Site Number : 8400009
- Downtown L.A. Research Center- Site Number : 8400009
- IMAX Clinical Trials- Site Number : 8400109
What taking part in a chronic disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting chronic disease studies in California.
Common questions
- Are there chronic disease clinical trials near Los Angeles?
- Yes. We're currently tracking 67 recruiting chronic disease studies with a site near Los Angeles, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a chronic disease study near Los Angeles?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Los Angeles to take part?
- Not necessarily. These studies have a site near Los Angeles, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New chronic disease studies open near Los Angeles regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.