Clinical trials · Los Angeles, CA
Chronic Disease clinical trials in Los Angeles
We’re tracking 66 recruiting chronic disease studies with a site in or near Los Angeles — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Los Angeles
- NCT06876363RecruitingPhase 1/Phase 2
Gene therapy study for X-linked chronic granulomatous disease
This study tests a new gene therapy called EN-374 for people with X-linked chronic granulomatous disease (X-CGD). It aims to fix the genetic cause of the disease to prevent severe infections and inflammation.
Los Angeles, CaliforniaAges 3 months+ - NCT06559176Enrolling by invitationPhase 1/Phase 2
Gene editing trial for chronic granulomatous disease
This trial tests a new gene editing treatment called PM359 for people with a specific type of chronic granulomatous disease (CGD) caused by a delGT mutation in the NCF1 gene. The goal is to see if it's safe and helps fight infections and inflammation.
Los Angeles, CaliforniaAges 6 years+ - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+ - NCT06376994RecruitingPhase 3
Clean air study for COPD
This study tests if using air cleaners at home improves lung health in people with COPD. If you qualify, you may get an air cleaner for your home and be followed for 12 months.
Los Angeles, CaliforniaAges 40 years+ - NCT07391904Enrolling by invitation
Testing lab result communication for older adults
This study tests a tool designed to help older adults understand their lab results more easily. Researchers want to see if the tool improves patient understanding and engagement.
Los Angeles, CaliforniaAges 65 years+ - NCT06476132RecruitingPhase 2
Belumosudil for lung transplant patients at risk of chronic rejection
This trial tests whether the drug Belumosudil can help prevent chronic lung rejection in people who recently had a lung transplant and showed signs of early rejection. It may improve long-term lung health.
Los Angeles, CaliforniaAges 12 years+ - NCT06878261RecruitingPhase 3
Tezepelumab for moderate to very severe COPD
This study tests a new medication called tezepelumab (given as a shot) to see if it can reduce COPD flare-ups in people with moderate to very severe COPD who have had recent flare-ups despite using inhalers. It may be an option for those with higher levels of eosinophils (a type of white blood cell) in their blood.
Los Angeles, CaliforniaAges 40–80 - NCT05919511Recruiting
Questionnaire study for people at risk after stem cell transplant
This observational study follows people who had a stem cell transplant a few months ago to better understand risk for chronic graft-versus-host disease. You won’t get a study treatment; instead, you’ll complete questionnaires over time, and the study team looks at your symptoms and experiences.
Los Angeles, CaliforniaAges 18 years+ - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Los Angeles, CaliforniaAges 18–75 - NCT06016257Recruiting
Virtual home exercise program for shoulder rehab
This study tests a virtual home exercise program (VirtuaCare) for people with shoulder problems who need physical therapy. It aims to see if doing exercises at home with virtual guidance works as well as standard care.
Los Angeles, CaliforniaAges 18 years+ - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Glendale, CaliforniaAges 18–75 - NCT06283966RecruitingPhase 3
Triple inhaler for COPD with heart risk
This study tests a triple-combination inhaler (budesonide, glycopyrronium, and formoterol) to see if it can help protect the heart and lungs in people with COPD who also have heart problems or high risk for them.
Inglewood, CaliforniaAges 40–80 - NCT04684602RecruitingPhase 1/Phase 2
Study of stem cells for several short- and long-term illnesses
This early-stage study tests whether injections of mesenchymal stem cells can be safe and helpful for certain chronic (long-term) and acute (short-term) conditions. You might be considered if you can consent, are able to return for follow-up visits, and do not have key reasons that would make stem-cell treatment unsafe.
Culver City, CaliforniaAges 18 years+ - NCT06531824RecruitingPhase 3
Heart and kidney protection study for chronic kidney disease
This study tests a new medicine (BI 690517) combined with empagliflozin to see if it can help protect the heart and kidneys in people with chronic kidney disease. It may slow down kidney disease progression and reduce heart risks.
Beverly Hills, CaliforniaAges 18 years+ - NCT05001009Enrolling by invitation
Goals of care conversation support for certain serious illnesses
This study helps primary care clinicians and their patients have structured “goals of care” conversations (about what matters most and care preferences). It may help you get clearer, earlier planning—especially if you have a serious illness and higher risk of hospitalization or death.
West Los Angeles, CaliforniaAges 18 years+ - NCT05465044Recruiting
Twice-weekly dialysis vs three times for new dialysis patients
This trial tests whether starting hemodialysis more gently (2 times per week) is as safe and effective as the usual schedule (3 times per week) for people early in dialysis. It may help some patients feel better with fewer dialysis sessions while closely monitoring kidney-related measurements.
West Los Angeles, CaliforniaAges 18 years+ - NCT06970977Recruiting
Chronic sinusitis questionnaire validation study
This study is testing a new questionnaire to better understand chronic sinusitis symptoms. It may help improve how doctors diagnose and treat the condition.
Santa Monica, CaliforniaAges 18 years+ - NCT04042844RecruitingPhase 2
Single injection treatment for chronic low back disc pain
This Phase 2 study tests whether one injection of BRTX 100 can reduce pain and improve function in people with chronic, disc-related low back pain. It looks for whether the treatment is safe and works better than what you’ve already tried.
Santa Monica, CaliforniaAges 18 years+ - NCT07091019Recruiting
CML patient experience study on standard TKI therapy
This study tracks the experiences and health outcomes of people with chronic myeloid leukemia (CML) who are taking approved first or second line tyrosine kinase inhibitor (TKI) medicines. It helps doctors learn how these treatments work in everyday care.
Torrance, CaliforniaAges 18–100 - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Torrance, CaliforniaAges 18 years+ - NCT06883305RecruitingPhase 3
Testing tezepelumab for moderate to severe COPD
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
Torrance, CaliforniaAges 40–80 - NCT05514184Enrolling by invitation
Diet coaching for diabetes and kidney disease to delay dialysis
This study tests a plant-focused diet plan to help people with diabetes and moderately to severely reduced kidney function avoid or delay needing dialysis. You would get diet instructions based on your random group and have several follow-up visits and check-ins over 6 months.
Torrance, CaliforniaAges 18 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
Torrance, CaliforniaAges 18–95 - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+
Hear when a new Chronic Disease trial opens near Los Angeles, CA
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Chronic Disease trials in other cities
Where these studies are running near Los Angeles
Institutions with a site for the recruiting chronic disease studies listed above.
- Research Site · 4 studies
- The Lundquist Institute at Harbor-UCLA Medical Center · 4 studies
- University of California, Los Angeles (UCLA) · 4 studies
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA · 2 studies
- Ark Clinical Research
- California Liver Research Institute
- Cedars-Sinai Medical Center
- City of Hope Comprehensive Cancer Center
What taking part in a chronic disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting chronic disease studies in California.
Common questions
- Are there chronic disease clinical trials near Los Angeles?
- Yes. We're currently tracking 66 recruiting chronic disease studies with a site near Los Angeles, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a chronic disease study near Los Angeles?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Los Angeles to take part?
- Not necessarily. These studies have a site near Los Angeles, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New chronic disease studies open near Los Angeles regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.