Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Hershey, PennsylvaniaAges 18 years+ - NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT07438288Recruiting
Predicting Liver Failure in People with Cirrhosis
This study follows people with liver cirrhosis—a condition where the liver is scarred—to see who gets worse or develops sudden liver failure. The goal is to find early warning signs so doctors can help prevent serious problems.
SingaporeAges 18 years+ - NCT07690202Recruiting
Living with kidney disease without dialysis or transplant
This study looks at the experiences of women of childbearing age who have chronic kidney disease but are not on dialysis or have not had a kidney transplant. The goal is to understand how the disease affects their lives.
CaenAges 18 years+ - NCT07673822Enrolling by invitation
Heart, kidney, and metabolic disease study in Korea
This study looks at how common heart, kidney, and metabolic problems are in Korea by using health insurance records. It will help doctors understand how often these conditions happen together.
SeoulAges 19 years+ - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT05410275RecruitingPhase 3
Low-dose rivaroxaban for dialysis patients without blood thinners
This study tests whether a lower dose of the blood thinner rivaroxaban is safe for people with kidney failure on dialysis who do not already need blood thinners. The goal is to find a way to prevent blood clots and strokes with less risk of bleeding.
ToursAges 18 years+ - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT04334031Recruiting
Hospital follow-up study for immune-related disease
This is a study that follows people with an immune-related illness at Lille University Hospital to better understand their care needs over time. By collecting information regularly, the study may help improve how future patients are monitored and treated.
LilleAges 18 years+ - NCT06657274Recruiting
Digital brain training for early memory problems
This study tests a smart digital program (app or computer-based) to help with memory, thinking, and daily life in people with early Parkinson's, mild cognitive impairment, or early memory concerns. It uses brain stimulation (TMS) along with cognitive exercises.
Brescia, ITAges 18–85 - NCT07149688Recruiting
Heart disease health program for older adults in Qujiang
This study follows older adults in Qujiang District who have chronic heart or blood vessel conditions. It aims to improve care through village-based management and help researchers better understand how to support long-term heart health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07284641RecruitingPhase 2
Stem cell transplant for immune disorders
This trial tests a stem cell transplant to treat common variable immunodeficiency (CVID) and other immune problems. It aims to replace a faulty immune system with a healthy one from a donor.
Pittsburgh, PennsylvaniaAges 5–40 - NCT00128973Recruiting
Study immune system problems in people with unusual infections
This study looks at how the immune system works in people who have abnormal immune function, often shown by unusual or repeated infections or long-lasting inflammation. It may involve tests using blood samples and storage of blood for future research.
Bethesda, MarylandAges Any age - NCT07771855RecruitingPhase 2
Antibody treatment for chronic lung disease after stem cell transplant
This study tests a new antibody medicine called tezelumab for patients who develop a breathing problem called bronchiolitis obliterans syndrome (BOS) after a stem cell transplant. The trial aims to see if this medicine can reduce flare-ups and improve lung function.
BesançonAges 18 years+ - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT07722585RecruitingPhase 1
New tablet study: absorption and food effects
This study tests a new form of the drug nurandociguat tablet to see how well it is absorbed compared to the old tablet, and whether food changes how it works. Healthy volunteers are needed to take the tablets and have their blood levels checked.
BerlinAges 18–58 - NCT07481526Recruiting
Chronic kidney disease registry study
This study is collecting information from people with chronic kidney disease (CKD) to understand how the disease progresses over time. It does not test any new treatments, so you keep your usual care.
Anning, Yunnan - South RegionAges Any age - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT06479252Recruiting
Comparing ways to test sit-to-stand in chronic lung disease
This study compares three ways of doing a simple sit-to-stand test for people with chronic lung disease: at the clinic, at home with video supervision, or on your own at home. The goal is to see which option works best and is easiest for patients.
Toronto, OntarioAges 18 years+ - NCT06463366Recruiting
Using MRI to better diagnose liver fat, inflammation, and scarring
This study uses advanced MRI scans to get a clearer picture of liver fat, inflammation, and scarring in people with chronic liver disease. It aims to help doctors diagnose and understand liver problems better.
Shenyang, LiaoningAges 18–75 - NCT06300788Recruiting
Pyrophosphate study in children with kidney disease
This study looks at a natural chemical in the body called pyrophosphate (PPi) in children with chronic kidney disease. It aims to understand how kidney problems affect this chemical, which is important for bone health. The study needs kids with different kidney stages, including those on dialysis, with a transplant, or even healthy kids having surgery for comparison.
Nice, Alpes-MaritimesAges birth–18 years
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,260 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.