Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06280443Recruiting
Frailty and muscle loss in chronic lung disease
This study looks at people with COPD or ILD who also show signs of frailty. It aims to understand how frailty and muscle loss (sarcopenia) affect their care and use of medical resources over time.
TaichungAges 20 years+ - NCT06153147Recruiting
Kidney & blood pressure in childhood cancer survivors
This study looks at kidney health and blood pressure in childhood cancer survivors. If you finished high-risk cancer therapy about 3 years ago, researchers want to see how your kidneys and blood pressure are doing now.
Toronto, OntarioAges Up to 19 years - NCT06382233Recruiting
The PRO-FUTURE study for children with kidney blockage
This study looks at how well a certain treatment works for children with a blockage in one kidney (unilateral UPJO). It may help your child avoid more serious kidney problems.
Naples, CampaniaAges 1 day–5 years - NCT05204212Recruiting
Heart procedure to close an atrial clot risk pouch in kidney failure
This trial tests a heart procedure that closes a part of the heart called the left atrial appendage to help prevent stroke in people with an irregular heartbeat (atrial fibrillation) and very advanced kidney disease. It’s mainly for patients who can take the needed blood-thinner medicines and who do not already have a clot in that pouch.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06416761Recruiting
Genetics and kidney disease progression study
This study looks at how genetics affect the progression of kidney diseases. Joining may help researchers understand your condition better and find better treatments.
MilanAges 18 years+ - NCT07835945Recruiting
Testing blood gas from artery vs fingertip in breathing distress
This trial compares blood drawn from an artery (arterial blood gas) with blood from a fingertip (capillary blood gas) to see if the fingertip test gives accurate enough results for patients in the emergency room with breathing problems caused by COPD or heart failure. It might help reduce the pain and discomfort of repeated artery tests.
NiceAges 18 years+ - NCT07826767RecruitingPhase 1/Phase 2
Gene therapy for inherited immune disease
This trial tests a new gene therapy (SGX-001) for chronic granulomatous disease caused by a specific genetic change. The treatment tries to fix the gene in your immune cells so they can fight infections better, and the trial will follow participants for up to 15 years to make sure it's safe and effective.
UlmAges 1.5 years+ - NCT07820644Recruiting
Liver cancer risk prediction in chronic liver disease
This study aims to predict the risk of developing liver cancer in people with chronic liver conditions such as hepatitis B or C, cirrhosis, or fatty liver disease. By participating, you may help researchers improve early detection and prevention strategies for liver cancer.
Shenzhen, GuangdongAges 18–75 - NCT05570929Recruiting
Study of kidney changes before and around donation
This study follows people who are planning kidney donation or a kidney transplant to better understand how kidney function changes over time. It may help researchers predict risk and improve care by studying health markers in detail.
BerlinAges 18–75 - NCT07810283Enrolling by invitation
Using a new imaging belt to guide breathing support
This study tests a new belt that takes pictures of your lungs to help doctors adjust your breathing support. It may help make non-invasive ventilation (a mask that helps you breathe) more comfortable and effective for people with chronic breathing problems.
LondonAges 18 years+ - NCT07804316Recruiting
Food choice app for chronic kidney disease patients
This study tests a mobile app that helps people with chronic kidney disease (CKD) make healthier food choices. It aims to empower you to manage your condition better through daily food tracking and personalized guidance.
SingaporeAges 21 years+ - NCT06532110Recruiting
Gut bacteria study in chronic digestive diseases
This study looks at the bacteria in your gut (the microbiome) in people with chronic gut conditions. Researchers want to understand how gut bacteria differ in these conditions to help improve treatments.
Hamilton, OntarioAges 18–75 - NCT06571344Recruiting
Vitamin D in dialysis patients
This trial checks if measuring vitamin D in dialysis patients can lead to better treatment, then gives vitamin D supplements to those who are low. It may help improve your bone and heart health.
GdanskAges 18 years+ - NCT05056701Recruiting
Checking early care for kidney disease after pre-eclampsia
This study looks at how to predict and diagnose chronic kidney disease (long-term kidney damage) in people who had pre-eclampsia during pregnancy, including related serious conditions. It may help identify kidney problems earlier so care can start sooner.
AngersAges 18 years+ - NCT06601231Recruiting
Better liver cancer screening with GAAD score and imaging
This study looks at whether adding a blood test (the GAAD score) to standard imaging can better detect liver cancer at an early stage in people with chronic liver disease. It may help you if you have cirrhosis or certain types of liver scarring.
Rotterdam, CAAges 18 years+ - NCT07741292RecruitingPhase 4
Kidney health study for older adults not on dialysis
This study tests whether a traditional Chinese medicine called Niaoduqing Granules can help improve kidney function in people over 60 with chronic kidney disease. It may offer a new way to manage the condition without dialysis.
Shanghai, Shanghai MunicipalityAges 61 years+ - NCT07725497RecruitingPhase 2
Luspatercept for anemia from chronic kidney disease
This trial tests a drug called luspatercept to see if it can raise hemoglobin levels in people with anemia caused by chronic kidney disease. It's for those whose current treatments aren't working well or who cannot use them.
Basking Ridge, New JerseyAges 18 years+ - NCT07722585RecruitingPhase 1
New tablet study: absorption and food effects
This study tests a new form of the drug nurandociguat tablet to see how well it is absorbed compared to the old tablet, and whether food changes how it works. Healthy volunteers are needed to take the tablets and have their blood levels checked.
BerlinAges 18–58 - NCT07715500Recruiting
MRI of Bile Ducts in Living Liver Donors
This study uses an MRI scan to look at the bile ducts in healthy people who want to donate part of their liver. The goal is to see if the scan can help predict and prevent bile duct problems for the person receiving the liver.
New DelhiAges 18–55 - NCT07712679Recruiting
Studying Kidney Scarring with FAPI PET/CT
This study uses a special PET/CT scan to look for scarring in the kidneys. The goal is to see if the scan can detect kidney fibrosis better than current methods.
Vienna, State of ViennaAges 18 years+ - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT07694791Recruiting
Gut health supplements for people on peritoneal dialysis
This trial tests whether taking probiotic and prebiotic supplements can improve gut health in people receiving peritoneal dialysis at home. It may help with digestion and overall well-being.
Monterrey, Nuevo LeónAges 18 years+ - NCT07685353Recruiting
Genes and graft fat after liver transplant study
This study looks at how genetic differences between liver donors and recipients affect fat buildup in the new liver after transplantation. It may help doctors understand why some transplanted livers develop steatosis (fatty liver) after the surgery.
New DelhiAges 18 years+ - NCT07684326RecruitingPhase 2/Phase 3
Can dapagliflozin help liver cirrhosis with fluid buildup? (Phase 2/3 randomized trial)
This trial tests a diabetes pill (dapagliflozin) to see if it helps people with liver cirrhosis and fluid buildup (ascites). The goal is to improve fluid balance and possibly reduce hospital stays.
GizaAges 18 years+
Hear when a new Chronic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.