Clinical trials
Chronic Kidney Disease Stage 3 clinical trials
Below are recruiting chronic kidney disease stage 3 clinical trials, each written for real people, not researchers. We’re tracking 196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04397159Recruiting
Exercise program to reduce tiredness in some kidney patients
This trial studies whether doing a combination exercise program can reduce “fatigability,” meaning feeling unusually tired or weak during activity, in Veterans with moderate-to-advanced chronic kidney disease. It also compares results with people without kidney disease and checks for safety, especially for heart and joint health.
Washington D.C., District of ColumbiaAges 50–85 - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80 - NCT03573089Recruiting
Testing higher vs standard phosphate targets in dialysis patients
This trial compares two treatment goals for blood phosphate levels in people with end-stage kidney disease who are on dialysis. It may help determine which target is safer and works better in real-world care.
Camperdown, New South WalesAges 18 years+ - NCT03032835Recruiting
Research study for calciphylaxis skin lesions
This study collects and stores information from people with calciphylaxis, a serious condition that causes painful skin lesions. It may help researchers learn more about the disease and improve future care.
Boston, MassachusettsAges 18 years+ - NCT02947750RecruitingPhase 2
Exercise study in people with kidney disease
This Phase 2 study tests how engaging in supervised exercise affects the body’s blood-vessel responses in people with chronic kidney disease (CKD) who don’t exercise regularly. It may help researchers understand whether exercise could be beneficial for CKD-related health changes.
Atlanta, GeorgiaAges 18–75 - NCT03716401Recruiting
Imaging tests to predict kidney disease in type 2 diabetes
This study uses special kidney imaging to look for patterns that can predict how diabetic kidney disease may progress. It may help researchers find better ways to identify people at higher risk using noninvasive (and possibly biopsy-related) tests.
TurkuAges 18–80 - NCT07271186RecruitingPhase 2
Study of an experimental drug for kidney disease from type 2 diabetes
This study tests an investigational drug called ALN-ANG3 to see if it can help people with diabetic kidney disease. The drug may reduce kidney damage and slow down the loss of kidney function. If you join, you will get the study drug or a placebo (a dummy shot) and be followed by a study doctor.
Huntsville, AlabamaAges 18–80 - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06917950RecruitingPhase 1/Phase 2
Roxadustat for bone and brain health in dialysis patients
This study tests whether roxadustat, a medicine for anemia, can also help with bone problems and mood or thinking issues in people on hemodialysis.
Al Mansurah, DakahliyaAges 18 years+ - NCT07134595Recruiting
Comparing two peritoneal dialysis schedules in children with kidney failure
This trial tests a modified version of daily peritoneal dialysis (M-CAPD) versus the standard version (C-CAPD) for children in low-resource settings who have end-stage kidney disease. It aims to see if the modified schedule works better for clearing waste and fluid.
Manila, ErmitaAges 2–18 - NCT07661940RecruitingPhase 2
SP16 for kidney protection during heart surgery
This trial tests a drug called SP16 to see if it can prevent acute kidney injury in people with chronic kidney disease who are having elective heart surgery with a heart-lung machine. It aims to help preserve kidney function after surgery.
Erlangen, BavariaAges 18 years+ - NCT05715814RecruitingPhase 3
Test diabetes-pill type medicine on kidney dialysis safety
This Phase 3 trial studies the safety of an SGLT2 inhibitor (a diabetes medication that can affect kidney fluid handling) in people on peritoneal dialysis. The goal is to see how the treatment works in your type of dialysis and whether it causes any problems.
Toronto, OntarioAges 18 years+ - NCT05189925RecruitingPhase 1
Correcting a missing immune enzyme using an mRNA cell therapy
This early-phase trial tests whether an mRNA-based treatment can correct a key immune problem in people with chronic granulomatous disease (CGD). It may help your immune cells work better against infections, but this is mainly to check safety and early signs of benefit.
Bethesda, MarylandAges 18–75 - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT05878171Recruiting
Choices about life-saving treatment for kidney failure patients
This trial looks at what patients with kidney failure prefer for life-sustaining treatments (like whether they would want certain life-prolonging care). Your answers may help improve how future care plans are discussed and tailored to patients’ wishes.
TaipeiAges 20 years+ - NCT07454174Recruiting
Study of a dietary program for polycystic kidney disease
This study tests a special medical food (Ren-Nu) to see if it helps with metabolism and kidney health in people with ADPKD. You would follow a dietary program and attend online classes.
Cleveland, OhioAges 18 years+ - NCT06903559RecruitingPhase 1/Phase 2
Roxadustat for heart and nutrition in dialysis patients
This study tests whether roxadustat can help improve heart health, nutrition, and reduce inflammation in people on hemodialysis. It may offer a new treatment option for anemia related to kidney disease.
Al Mansurah, DakahliyaAges 18 years+ - NCT03979534Recruiting
Protecting Kidneys With a Low-Protein Diet
This study tests whether a step-by-step low-protein diet can help protect your kidneys if you have advanced chronic kidney disease (stages 4 or 5) or stage 3 that is getting worse quickly. The goal is to see if this diet approach can slow down kidney damage.
La FlècheAges 18 years+ - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT07854561RecruitingPhase 2
Romiplostim plus ESAs for dialysis anemia
This trial tests whether adding romiplostim (a medication that helps increase blood cells) to standard ESA therapy can improve anemia in people on dialysis who have not responded well to ESAs alone.
Hong KongAges 18 years+ - NCT06571344Recruiting
Vitamin D in dialysis patients
This trial checks if measuring vitamin D in dialysis patients can lead to better treatment, then gives vitamin D supplements to those who are low. It may help improve your bone and heart health.
GdanskAges 18 years+ - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT07374042RecruitingPhase 3
A supplement to protect muscle in advanced kidney disease
This trial tests whether a special diet supplement (Ketoanalogue) can help protect your muscles while you follow a moderate protein diet. It is for people with chronic kidney disease stage 4 or 5 who are not on dialysis or have not had a kidney transplant.
Clermont-FerrandAges 18–100 - NCT06886282Recruiting
How colon cancer and kidney disease are linked: a imaging and gene study
This trial uses advanced imaging and genetic tests to understand how colon cancer and chronic kidney disease may be connected. It may help decide the best treatment for people with both conditions.
NaplesAges 18 years+
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Common questions
- Are there clinical trials for chronic kidney disease stage 3?
- Yes. Clin2 currently lists 196 recruiting chronic kidney disease stage 3 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease stage 3 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease stage 3 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.