Clinical trials
Chronic Neuropathic Pain clinical trials
Below are recruiting chronic neuropathic pain clinical trials, each written for real people, not researchers. We’re tracking 119 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06689345Enrolling by invitation
Brain stimulation study for chronic pain including post-COVID
This study tests if a non-invasive brain stimulation technique can reduce pain in people with chronic pain conditions like fibromyalgia, headaches, or pain that started after COVID-19. It is looking for healthy people and people with ongoing pain to see if the treatment helps.
Sâo Bernardo Do Campo, São PauloAges 18–64 - NCT06023706RecruitingPhase 3
Capsaicin patch for tailbone pain
This trial tests a capsaicin 8% patch — a pain-relieving skin patch — to see if it can reduce tailbone pain that has lasted more than 3 months. You may be eligible if you have tried other treatments without success and have nerve-related pain symptoms.
BrestAges 18 years+ - NCT06264297Recruiting
Nerve radiofrequency treatment for chronic leg pain
This trial tests a new type of treatment (high-voltage pulsed radiofrequency) that uses a special needle to deliver energy to the nerve root in your lower back. The goal is to see if it can reduce chronic leg pain caused by a pinched or irritated nerve.
Terrassa, BarcelonaAges 18 years+ - NCT06490484RecruitingPhase 2
A new capsule for diabetic nerve pain when pregabalin doesn't work
This trial tests an experimental drug (HSK16149) for people with long-term diabetic nerve pain that hasn't been helped enough by pregabalin. It aims to see if the new capsule can reduce pain more effectively.
Hangzhou, ZhejiangAges 18–75 - NCT06438471RecruitingPhase 1
Study of a new drug for nerve pain after spinal cord injury
This trial tests an experimental pill for people with spinal cord injury who have long-term nerve pain. It aims to see if the drug can reduce pain and be safe.
Augusta, GeorgiaAges 18 years+ - NCT07493226Recruiting
NSAIDs for Frozen Shoulder Pain Study
This study tests different types of nonsteroidal anti-inflammatory drugs (NSAIDs) to see which works best for people with frozen shoulder. It may help you if you have ongoing shoulder pain and stiffness without other shoulder injuries.
Konya, SelçukluAges 18–75 - NCT06044584Recruiting
AI tool for tracking pain after injury or nerve pain
This study tests a smartphone-based tool that uses artificial intelligence to track your pain and how it affects your daily life. It may help you and your doctor better understand your pain over time.
Pietra Ligure, SavonaAges 18–80 - NCT06430918Enrolling by invitation
Nerve pain and sleep quality in knee osteoarthritis
This study looks at how nerve pain and sleep quality are related in people with knee osteoarthritis. It aims to help doctors better understand and treat pain.
IzmirAges 18–80 - NCT06398847Recruiting
Virtual reality self-hypnosis for HIV-related pain
This study tests if using a virtual reality (VR) headset for self-hypnosis can help people with HIV manage chronic pain. You would practice at home with a smartphone app, and researchers will track your pain levels over time.
New York, New YorkAges 18 years+ - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT07408193RecruitingEarly Phase 1
Lidocaine and ketamine for severe cancer pain not helped by opioids
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
Athens, AtticaAges 18 years+ - NCT05052541RecruitingPhase 3
Oral cannabis for long-term spine pain
This trial studies whether taking cannabis by mouth can safely reduce chronic spine pain and improve daily comfort. You may be eligible if you have long-lasting spine pain and can follow study rules about stopping or limiting other cannabis and certain other treatments.
Aurora, ColoradoAges 21–84 - NCT06466330Recruiting
Knee embolization for post-replacement pain
This trial tests a non-surgical treatment called microparticle geniculate artery embolization for people with persistent knee pain after a total knee replacement. It aims to reduce pain by blocking tiny blood vessels that may be causing inflammation.
CréteilAges 40–80 - NCT06596681RecruitingEarly Phase 1
Study of GA for hard-to-treat nerve pain
This early-phase trial tests a new treatment called GA for people with hard-to-treat neuropathic pain that hasn't improved with standard therapies. The goal is to see if it is safe and tolerable.
Beijing, Beijing MunicipalityAges 18–65 - NCT06185816RecruitingPhase 2/Phase 3
Non-invasive pulsed radiofrequency for nerve pain
This trial tests a non-invasive treatment called pulsed radiofrequency for people with chronic nerve pain after an injury. It uses a device that sends short bursts of energy to the painful area to help reduce pain without surgery.
Redwood City, CaliforniaAges 18 years+ - NCT07677631Recruiting
Emotional allodynia in fibromyalgia: a questionnaire study
This study compares how people with fibromyalgia and those with other long-term pain conditions experience emotional pain (like feeling hurt by emotions). You will fill out a questionnaire about emotional sensitivity. The goal is to see if emotional allodynia (pain from emotions) is more common in fibromyalgia.
BariAges 18 years+ - NCT06614322RecruitingPhase 2
Testing Pain Sensitivity and Pain Relief for Nerve Pain in Feet
This study looks at how people with long-term nerve pain in their feet respond to pain relief. It aims to match the right treatment to each person based on their pain sensitivity.
Boston, MassachusettsAges 18–80 - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT07544108Recruiting
Understanding What Affects Neck Pain Recovery
This study helps researchers understand which patients with long-term neck pain recover better and why. By learning more about your neck pain and how it affects your daily life, the study may help doctors predict outcomes and improve treatment.
Kütahya, KütahyaAges 18–65 - NCT06209645Recruiting
Personalized brain stimulation for stubborn nerve pain relief
This study tests a non-invasive, personalized brain stimulation technique to reduce nerve pain that has not responded to standard treatments. It may be a good option if you have had nerve pain for over a year and have already tried other pain medications without enough relief.
BronAges 18–80 - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT06603792RecruitingEarly Phase 1
Neurofeedback for diabetic nerve pain
This trial tests whether a brain-training technique called neurofeedback can help reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have had moderate-to-severe nerve pain for at least 3 months.
OdenseAges 18–82 - NCT07000409Recruiting
Ultrasound-guided nerve block for shingles pain
This trial tests if a nerve block with betamethasone can reduce long-term shingles pain on the trunk. It may help people who still have pain more than 3 months after the rash appeared.
CairoAges 18–75 - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+
Hear when a new Chronic Neuropathic Pain trial opens
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Common questions
- Are there clinical trials for chronic neuropathic pain?
- Yes. Clin2 currently lists 119 recruiting chronic neuropathic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic neuropathic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic neuropathic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.