Clinical trials
Chronic Neuropathic Pain clinical trials
Below are recruiting chronic neuropathic pain clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05537935RecruitingPhase 4
Low-dose naltrexone for nerve pain in people with HIV
This trial studies whether a low dose of naltrexone can reduce long-lasting nerve-related pain in adults living with HIV. It may help if your pain has been ongoing and you have stable HIV control.
Atlanta, GeorgiaAges 18–75 - NCT06129890Recruiting
Brain stimulation for nerve pain and depression
This trial tests whether a noninvasive brain stimulation technique (rTMS) can help people with long-term nerve pain who also have depression. It aims to see if this treatment can reduce pain and improve mood.
Saint-EtienneAges 18–85 - NCT06250491Recruiting
Deep rTMS for Nerve Pain or Fibromyalgia
This study is testing a special type of brain stimulation (deep rTMS) for people with long-term nerve pain or fibromyalgia. The goal is to see if it can help reduce pain that hasn't gotten better with usual treatments.
Boulogne-BillancourtAges 18–80 - NCT06452615Recruiting
Shock wave therapy for nerve pain after mastectomy
This study tests if a treatment called extracorporeal shock wave therapy (using sound waves from outside the body) can help relieve nerve pain that some women have after a mastectomy. It may be an option if you have burning, tingling, or numbness in your chest, armpit, or upper arm that started after your surgery.
CairoAges 40–65 - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT06969456Recruiting
Exercise and nerve stimulation for chronic back pain
This study looks at whether combining exercise with a type of nerve stimulation (called neuromodulation) can help people with long-term spinal pain that has nerve involvement. It may be an option if you have had pain for at least 6 months and it is severe.
Valencia, ValenciaAges 18–70 - NCT07301177Recruiting
Magnetic stimulation for veterans with nerve pain after injury
This study tests whether a non-invasive magnetic stimulation treatment can help veterans with long-term nerve pain after an injury or surgery. It may offer a drug-free option to reduce pain and improve quality of life.
San Diego, CaliforniaAges 18 years+ - NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Scottsdale, ArizonaAges 18 years+ - NCT06029075Recruiting
Brain stimulation for nerve pain after spinal injury
This study tests whether a gentle electrical current applied to the scalp can help relieve nerve pain that continues after an injury to the spinal cord, arm or leg amputation, or brain injury. Participants will continue their usual pain medications during the trial.
Houston, TexasAges 18–75 - NCT07497425Recruiting
Exercise and Immune Response in Chronic Back Pain
This study looks at how a single session of exercise affects your immune system and nervous system. It may help researchers find new ways to treat chronic low back pain.
Montreal, QuebecAges 18–75 - NCT05811312Recruiting
Spinal cord stimulation and brain changes in chronic pain
This study uses non-invasive brain monitoring to see how spinal cord stimulation may change brain activity in people with chronic nerve pain. It aims to better understand how treatment affects the brain and pain over time.
Cleveland, OhioAges 18 years+ - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT06155916Recruiting
Sleep and nerve pain: a pregabalin study
This study tests whether a nerve pain medication (pregabalin) helps people with long-term nerve pain sleep better. It involves brain scans to see how the medication affects the brain.
Helsinki, HUSAges 18–75 - NCT06531317Recruiting
EEG and brain stimulation for nerve pain after spinal cord injury
This study tests whether a personalized brain stimulation treatment (using a non-invasive technique called tDCS) can help reduce nerve pain in people with spinal cord injury. The researchers will also use EEG (a cap that records brain activity) to see how your brain responds.
Badalona, BarcelonaAges 18–99 - NCT07214844Recruiting
Freezing vs. heating nerves for chronic low back pain
This study compares two procedures to treat long-term low back pain from the small joints in your spine. One uses extreme cold, the other uses heat to stop pain signals. It may help if you have had at least three months of back pain and other treatments haven't worked.
The Bronx, New YorkAges 18 years+ - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT07493213Recruiting
Ultrasound-guided shoulder injections for frozen shoulder
This study tests whether ultrasound-guided injections into the shoulder can improve pain and movement in people with frozen shoulder. It may help if you have had shoulder pain for at least 3 months and other treatments haven't worked well.
Konya, SelçukluAges 18–75 - NCT06817018RecruitingPhase 2
Ginger root extract for chronic sciatica pain
This study tests whether a ginger root extract can reduce pain in people with long-term sciatica. If you have had sciatic pain for at least 3 months and are not on blood thinners, you may be able to join.
Lubbock, TexasAges 18–85 - NCT06420141Recruiting
Nerve pain after ankle fracture surgery
This study looks at why some people develop nerve pain (neuropathic pain) after breaking their ankle and having surgery. If you have an ankle fracture that needs surgery, you may be able to join and help researchers understand this type of pain better.
Indianapolis, IndianaAges 18–85 - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT05484635Recruiting
Test removing mesh versus leaving it for groin pain
This study compares removing the pre-surgery mesh versus not removing it in people who have long-lasting groin pain after inguinal hernia repair. It may help doctors learn which approach best reduces ongoing pain.
Cleveland, OhioAges 18 years+ - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT06856642Recruiting
Comparing belly drawing exercises with ultrasound for chronic back pain
This study compares two types of physical therapy for chronic low back pain: one uses real-time ultrasound to help you learn a special belly-drawing maneuver, the other is standard physical therapy. The goal is to see which method reduces pain better.
BoluAges 18–65
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Common questions
- Are there clinical trials for chronic neuropathic pain?
- Yes. Clin2 currently lists 120 recruiting chronic neuropathic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic neuropathic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic neuropathic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.