Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07382258Recruiting
Inhaled nitric oxide for COPD: a clinical study
This trial tests whether a gas called nitric oxide, breathed in through the nose or mouth, can help people with moderate to severe COPD. It could improve breathing and quality of life.
Nanjing, JiangsuAges 40–75 - NCT07382986Recruiting
Study of a herbal compound for COPD in China
This trial tests a traditional Chinese herbal compound formula for people with COPD. It aims to see if the herbal treatment can help improve lung health when used on top of standard inhaler therapy.
Hebi, HenanAges 40–80 - NCT07394712Recruiting
A health program for COPD patients after rehab
This study tests a community-based maintenance program for people with moderate to severe COPD who have finished an initial 8-week pulmonary rehab. The goal is to help you stay active and keep your health gains.
Lleida, CataloniaAges 40–75 - NCT01177618Recruiting
Study of early-onset severe COPD in younger adults
This study looks at people who develop COPD (a long-term lung breathing problem) at a younger age and have severe airflow limitation. It may help researchers better understand COPD in early-onset patients and find ways to improve care for this group.
Boston, MassachusettsAges Any age - NCT07406048Recruiting
Effectiveness of a triple inhaler for COPD in Brazil
This study looks at how well a triple inhaler (BDP/FF/GB) works for people with severe COPD in Brazil. It may help those who have had at least one flare-up in the past year.
São Paulo, São PauloAges 40 years+ - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07418736RecruitingPhase 2
CM326 for moderate to severe COPD
This trial tests a new medicine called CM326 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve lung function.
Beijing, Beijing MunicipalityAges 40–85 - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07441226RecruitingPhase 2
Stem cells for advanced COPD treatment
This trial tests whether adding umbilical cord stem cells to standard triple therapy can help people with Group E COPD. It aims to see if this approach improves lung function and quality of life.
Jakarta, Jakarta Special Capital RegionAges 40–75 - NCT07469111Recruiting
Low-weight arm exercises with blood flow restriction for COPD patients
This trial tests whether doing light arm exercises while wearing a cuff that slightly restricts blood flow can help people with COPD improve their arm strength and function without heavy weights.
Malatya, BattalgaziAges 40–80 - NCT07472738Recruiting
Studying treatable traits in chronic airway diseases
This trial is studying people with chronic lung conditions, like COPD or asthma, to find treatable traits. It also includes healthy volunteers for comparison, to better understand what makes these diseases different and how to personalize treatment.
Beijing, Beijing MunicipalityAges 20–75 - NCT07477600RecruitingPhase 1/Phase 2
Stem cell therapy for moderate to severe COPD
This trial tests a new stem cell therapy for people with moderate to severe COPD who have not improved with standard treatments. The goal is to see if the therapy is safe and can help improve lung function.
Shenzhen, GuangdongAges 40–80 - NCT07482475Recruiting
COPD study for people getting lung cancer screening
This study looks at COPD in people who are already getting lung cancer screening. If you have COPD or a high risk for it, joining this observational trial may help researchers learn more about your condition.
Ann Arbor, MichiganAges 50–80 - NCT07069829Recruiting
Living with COPD: A study on Breztri/Trixeo
This study looks at how well a triple-combination inhaler called Breztri/Trixeo works for people with moderate to severe COPD. If you have been prescribed this inhaler but haven't started it yet, and you are between 30 and 80 years old, you may be able to join.
Buenos AiresAges 30–80 - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT07509606Recruiting
Whole body vibration for healthy adults and COPD patients
This study tests if a vibrating platform can help people with COPD and healthy adults. You stand on a machine that gently vibrates to improve muscle function and breathing.
TainanAges 18 years+ - NCT07519603Recruiting
Exercise program for older adults with COPD and frailty
This study tests whether a structured exercise and training program called VIVIFRAIL can help older adults with COPD feel stronger and more independent. You'll participate in guided physical activities designed to improve your strength and daily functioning.
Hanoi, HanoiAges 60 years+ - NCT07576894Recruiting
How the Heart Responds to Exercise in COPD Patients
This study looks at how the right side of your heart responds when you exercise, in people with COPD (a chronic lung condition). The goal is to understand this response better and potentially improve treatments.
Aurora, ColoradoAges 40 years+ - NCT07579052Recruiting
Predicting When Severely Ill COPD Patients Can Stop Breathing Machines
This study tests a prediction tool called CLEAR to help doctors know when patients with severe COPD lung disease are ready to stop using breathing machines (ventilators) in the ICU. The tool may help doctors make faster, safer decisions about when patients can breathe on their own.
Asyut, Assuit EgyptAges 40 years+ - NCT07583849RecruitingPhase 3
Testing a new inhaled powder for COPD symptoms
This study tests whether a new inhaled medication called HSK39004 can help people with COPD breathe better and reduce shortness of breath. You'll receive either the medication or a placebo (inactive powder) and be monitored for safety and effectiveness.
Beijing, Beijing MunicipalityAges 40–80 - NCT07604103RecruitingPhase 3
Heart Attack and Pneumonia Recovery Study With Vaccination
This study looks at blood markers (special proteins) in patients who have had both a heart attack and pneumonia, to see how vaccination affects recovery. The goal is to understand whether flu and pneumonia vaccines are safe and helpful for people recovering from these two serious conditions together.
Malang, East JavaAges 18–65 - NCT07605117Recruiting
Special Exercise Training for COPD Patients
This study tests a new type of exercise training called isoinertial training (using special equipment that adjusts resistance as you move) for people with moderate to severe COPD. The goal is to see if this training can help improve your breathing, strength, and ability to do daily activities.
Bogotá, Bogotá, DCAges 50–80 - NCT07646587RecruitingPhase 2
Safety Study of WIN378 for Moderate-Severe COPD
This study tests a new drug called WIN378 in people with moderate-to-severe COPD (chronic lung disease). It will check if the drug is safe and how the body processes it, which may help improve breathing and reduce flare-ups.
Miami Lakes, FloridaAges 40–80 - NCT07665931Recruiting
Testing Simeox for severe COPD with lung hyperinflation
This trial tests if a device called Simeox can reduce trapped air in the lungs of people with severe COPD. It may help you breathe easier if you have pulmonary hyperinflation.
Codogno, LombardyAges 18 years+
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 197 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.