Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 212 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07122544Recruiting
Salt chamber pulmonary rehab for COPD
This study tests whether doing pulmonary rehab (breathing and exercise training) in a salt chamber can help people with COPD breathe and feel better. It is for people whose COPD is stable and who can move independently.
Krakow, MałopolskaAges 18 years+ - NCT07112235Recruiting
COPD and cold virus study
This study looks at how the common cold virus affects people with COPD to find new treatments. If you have moderate COPD and your symptoms flare up when you catch a cold, you may be able to help.
LondonAges 40–75 - NCT07082738RecruitingPhase 2
Study of AZD6793 for people with moderate to very severe COPD
This trial tests a new drug called AZD6793 for people with moderate to very severe COPD. It aims to see if the drug can help improve breathing and reduce flare-ups.
Birmingham, AlabamaAges 40 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT06247397Recruiting
High-flow therapy for long-term oxygen users
This trial tests if adding high-flow oxygen therapy to your usual long-term oxygen therapy can help you breathe better. It is for people with COPD or ILD who use oxygen at home for at least 15 hours a day.
Karlskrona, Blekinge CountyAges 18 years+ - NCT07068438Recruiting
Pulsed electric field for chronic bronchitis
This study tests a new treatment that uses brief electric pulses to clear blocked airways in people with chronic bronchitis. It might help if you have a long-term cough with mucus and standard medicines aren't enough.
Hefei, AnuiAges 35–80 - NCT07069829Recruiting
Living with COPD: A study on Breztri/Trixeo
This study looks at how well a triple-combination inhaler called Breztri/Trixeo works for people with moderate to severe COPD. If you have been prescribed this inhaler but haven't started it yet, and you are between 30 and 80 years old, you may be able to join.
Buenos AiresAges 30–80 - NCT07074093Enrolling by invitation
Smartphone app to help COPD patients with air pollution
This study tests whether a smartphone app can help people with COPD breathe better by giving them tips to avoid air pollution. If you live in Salamanca and can use a smartphone, this app might help you manage your condition.
Salamanca, SalamancaAges 18 years+ - NCT07059091RecruitingPhase 2
Allergy medicine for COPD with indoor allergies
This study tests if omalizumab, an allergy medicine, can help people with COPD who are allergic to common indoor allergens and have had recent flare-ups. It aims to see if reducing allergic reactions can improve COPD control.
Birmingham, AlabamaAges 40 years+ - NCT07051707Recruiting
Study of a new lung treatment for people with COPD
This trial tests a device called dNerva that targets nerves in the lungs to help people with COPD breathe easier. It is designed for those who have moderate to severe COPD and are not currently smoking.
Birmingham, AlabamaAges 40–80 - NCT07053423RecruitingPhase 4
Dupilumab for COPD with airway inflammation
This study tests if a drug called dupilumab, given as a shot under the skin, can reduce airway inflammation in people aged 40-85 with moderate-to-severe COPD who also have signs of a specific type of inflammation called Type 2. It may help if you have frequent flare-ups and are already using multiple inhalers.
Birmingham, AlabamaAges 40–85 - NCT07039669RecruitingPhase 3
Study of 611 for moderate to severe COPD in adults
This trial tests a new medicine called 611 for people with moderate to severe COPD. It aims to see if adding 611 to your current treatments can help prevent flare-ups and improve symptoms.
Beijing, Beijing MunicipalityAges 40–85 - NCT07022704Recruiting
Doxapram to help COPD patients breathe easier off the ventilator
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Cairo, Cairo GovernorateAges 20–65 - NCT04664491Recruiting
Program to reduce COPD flare-ups with standardized care
This study tests whether a structured care program for COPD can lower how often your symptoms flare up. It may help by improving everyday management and preventing future worsening.
Beijing, Beijing MunicipalityAges 40 years+ - NCT07000604Recruiting
How inhaler use affects oral health in COPD patients
This study looks at how using a metered dose inhaler (a common type of inhaler) might impact your mouth and teeth if you have COPD. It aims to help understand and improve oral care for people using these inhalers.
ÇankırıAges 35–80 - NCT06986070RecruitingPhase 1
Stem cell therapy for mild to moderate COPD
This study tests whether a new type of stem cell (SMS cells) can help people with mild or moderate COPD caused by smoking or pollution. You will receive the treatment by inhalation and be followed to see if your breathing improves.
Melbourne, VictoriaAges 39–69 - NCT06724315Recruiting
Studying severe COPD in Brazil
This study follows people with severe or very severe COPD to learn more about their health over time. You may qualify if your COPD causes many symptoms or frequent flare-ups.
São Paulo, São PauloAges 18 years+ - NCT06976762Enrolling by invitation
Light-based muscle oxygen measurements in COPD with kidney disease
This study uses a special light-based device (near-infrared spectroscopy) to measure muscle oxygen levels in people who have both COPD and chronic kidney disease. Researchers want to see if these measurements can help predict how the disease progresses, which could lead to better monitoring and treatment.
Tokat ProvinceAges 18–80 - NCT06974981Recruiting
Using lung cancer screening to find and treat COPD
This study looks at how lung cancer screening can also help find and manage COPD, a lung condition that often goes undetected. If you are a current or former smoker and meet certain age and smoking history criteria, you may join to help improve screening and care for both lung cancer and COPD.
Philadelphia, PennsylvaniaAges 50–80 - NCT06959095RecruitingPhase 3
Depemokimab for adults with COPD and type 2 inflammation
This trial tests a new biologic medicine called depemokimab, given as an injection, to see if it reduces flare-ups (exacerbations) in people with COPD who have a specific type of inflammation (high eosinophils). It may help if you have frequent flare-ups despite using your regular inhalers.
Bakersfield, CaliforniaAges 40–80 - NCT06961214RecruitingPhase 3
Depemokimab for COPD with type 2 inflammation
This study tests a new biologic medicine, given as an injection, to see if it can reduce flare-ups in adults with COPD who have a certain type of inflammation. It may help people who still have frequent exacerbations despite using their current inhalers.
Sheffield, AlabamaAges 40–80 - NCT06958666Recruiting
Comparing two breathing exercises for COPD symptoms
This study compares two breathing exercise methods (DITM vs IMT) for people with COPD to see which helps improve symptoms and quality of life better. It's for people who are already using a specific type of inhaler.
Hangzhou, ZhejiangAges 40 years+ - NCT06956742Recruiting
Breathing device study for COPD shortness of breath after exercise
This trial tests a device that briefly opens your airways to help release trapped air after exercise. It may reduce shortness of breath and improve your daily life with COPD.
Rouen, NormandyAges 18 years+ - NCT06944925RecruitingPhase 1
Study of BBT002 for COPD and Nasal Polyps
This trial tests a new drug, BBT002, first in healthy volunteers and then in people with chronic obstructive pulmonary disease (COPD) or chronic sinusitis with nasal polyps. It aims to see if the drug is safe and how it works in the body.
Bowling Green, KentuckyAges 18–80
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 212 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.