Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07039669RecruitingPhase 3
Study of 611 for moderate to severe COPD in adults
This trial tests a new medicine called 611 for people with moderate to severe COPD. It aims to see if adding 611 to your current treatments can help prevent flare-ups and improve symptoms.
Beijing, Beijing MunicipalityAges 40–85 - NCT07051707Recruiting
Study of a new lung treatment for people with COPD
This trial tests a device called dNerva that targets nerves in the lungs to help people with COPD breathe easier. It is designed for those who have moderate to severe COPD and are not currently smoking.
Birmingham, AlabamaAges 40–80 - NCT07053423RecruitingPhase 4
Dupilumab for COPD with airway inflammation
This study tests if a drug called dupilumab, given as a shot under the skin, can reduce airway inflammation in people aged 40-85 with moderate-to-severe COPD who also have signs of a specific type of inflammation called Type 2. It may help if you have frequent flare-ups and are already using multiple inhalers.
Birmingham, AlabamaAges 40–85 - NCT07059091RecruitingPhase 2
Omalizumab for COPD with allergies
This trial tests if omalizumab, an allergy medication, can help people with COPD who have allergies to common indoor triggers like cat, dog, mouse, cockroach, or dust mite. It aims to reduce flare-ups and improve breathing.
Birmingham, AlabamaAges 40 years+ - NCT07068438Recruiting
Pulsed electric field for chronic bronchitis
This study tests a new treatment that uses brief electric pulses to clear blocked airways in people with chronic bronchitis. It might help if you have a long-term cough with mucus and standard medicines aren't enough.
Hefei, AnuiAges 35–80 - NCT07112235Recruiting
COPD and cold virus study
This study looks at how the common cold virus affects people with COPD to find new treatments. If you have moderate COPD and your symptoms flare up when you catch a cold, you may be able to help.
LondonAges 40–75 - NCT07118306Recruiting
COPD flare-up follow-up study
This study is for people with COPD who go to the emergency room for a moderate or severe flare-up. It looks at how they are doing after their visit and whether their current inhaler treatment is working well.
Park Ridge, IllinoisAges 40 years+ - NCT07122544Recruiting
Salt chamber pulmonary rehab for COPD
This study tests whether doing pulmonary rehab (breathing and exercise training) in a salt chamber can help people with COPD breathe and feel better. It is for people whose COPD is stable and who can move independently.
Krakow, MałopolskaAges 18 years+ - NCT07140328RecruitingPhase 2
Testing a new inhaler for COPD symptoms
This trial tests two forms of a new medication (HSK39004) in people with COPD. The goal is to see if they help improve breathing and are safe. Eligible participants must be between 40 and 80, have moderate to severe COPD, and be able to stop other COPD treatments during the study.
Nanchang, JiangsuAges 40–80 - NCT07177976Recruiting
Comparing two breathing exercises for COPD
This study compares two breathing techniques—Pilates breathing and pursed lip breathing—to see which one improves chest expansion and peak expiratory flow rate (how fast you can blow air out) in people with mild COPD.
RawalpindiAges 40–64 - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Chandler, ArizonaAges 40–80 - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Birmingham, AlabamaAges 40–80 - NCT07195838Recruiting
Mindful breathing for people with COPD
This study tests a mindful breathing program for people with COPD. It aims to help reduce stress and improve breathing. Participants use a smartphone or tablet to take part from home.
Hong KongAges 50–80 - NCT07212439Recruiting
Monitoring coughs to detect worsening COPD early
This study tests if monitoring your cough sounds can help detect a sudden worsening of COPD (a lung condition) sooner. It aims to find early warning signs so you can get treatment faster.
Pamplona, NavarreAges 18 years+ - NCT07259174Recruiting
Ultrasound for diaphragm in COPD flare-ups
This study uses ultrasound to measure how well your diaphragm muscle works during a COPD flare-up. The goal is to see if this measurement can help predict how you will recover.
Zwolle, OverijsselAges 18 years+ - NCT07285642Recruiting
Oxygen levels in muscles and brain in COPD patients
This study measures oxygen levels in your brain and leg muscles during exercise to understand how COPD affects them.
IstanbulAges 40–70 - NCT07292714RecruitingPhase 2
Testing 9MW1911 for people with moderate to severe COPD
This trial tests a new medication called 9MW1911 to see if it can help people with moderate to severe COPD who have had recent flare-ups. It is for current or former smokers ages 40 to 75 who are already on standard COPD treatments.
Chizhou, AnhuiAges 40–75 - NCT07293429Recruiting
Posture and breathing training for COPD with forward head posture
This study tests a program that combines posture correction and breathing muscle exercises for people with COPD who also have a forward head posture. It aims to improve breathing and reduce shortness of breath.
LahoreAges 40–60 - NCT07307781Recruiting
Study of COPD patients with frequent flare-ups in Moscow
This study tests a new treatment for people with COPD who still have frequent flare-ups despite using two maintenance inhalers. It aims to see if the study medicine can reduce these flare-ups.
MoscowAges 18–100 - NCT07319039Recruiting
Brain scan study of breathlessness in cancer, COPD, and heart failure
This study uses a brain scan (fMRI) to learn how the brain processes shortness of breath in people with advanced heart failure, COPD, or lung cancer. It aims to help doctors better understand and treat breathlessness.
Geneva, Canton of GenevaAges 18 years+ - NCT06944925RecruitingPhase 1
Study of BBT002 for COPD and Nasal Polyps
This trial tests a new drug, BBT002, first in healthy volunteers and then in people with chronic obstructive pulmonary disease (COPD) or chronic sinusitis with nasal polyps. It aims to see if the drug is safe and how it works in the body.
Bowling Green, KentuckyAges 18–80 - NCT07349524RecruitingPhase 2
A study of an oral tablet for COPD
This study tests an oral tablet called RSS0343 for people with moderate to severe COPD. It aims to see if the tablet can improve lung function and reduce flare-ups when added to your current breathing treatments.
Guangzhou, GuangdongAges 40–80 - NCT07351734RecruitingPhase 2
Testing JKN2403 for COPD: a new treatment option
This study tests an experimental drug called JKN2403 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve breathing compared to a placebo (a dummy pill).
Guangzhou, GuangdongAges 40–80 - NCT07355868RecruitingEarly Phase 1
Cell therapy for COPD
This trial is testing a new type of cell therapy called REGEND007 for people with COPD. It looks at whether the treatment can help improve how far you can walk and your overall breathing.
Yiwu, ZhejiangAges 40–80
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 197 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.