Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07339280Enrolling by invitation
Probiotics for COPD: symptoms, lungs, and inflammation
This study tests whether taking a probiotic can improve symptoms, lung function, and inflammation in people with COPD. It is for adults with stable COPD who have not had a flare-up or treatment change in the last two months.
KarlovacAges 18 years+ - NCT07074093Enrolling by invitation
Smartphone app to help COPD patients with air pollution
This study tests whether a smartphone app can help people with COPD breathe better by giving them tips to avoid air pollution. If you live in Salamanca and can use a smartphone, this app might help you manage your condition.
Salamanca, SalamancaAges 18 years+ - NCT06976762Enrolling by invitation
Light-based muscle oxygen measurements in COPD with kidney disease
This study uses a special light-based device (near-infrared spectroscopy) to measure muscle oxygen levels in people who have both COPD and chronic kidney disease. Researchers want to see if these measurements can help predict how the disease progresses, which could lead to better monitoring and treatment.
Tokat ProvinceAges 18–80 - NCT06882863Enrolling by invitation
Study to help reduce sitting in severe COPD
This study tests whether a nurse can help you sit less during the day if you have severe COPD. A nurse will visit you at home for motivational interviews to help you become more active.
RoskildeAges 65 years+ - NCT06851195Enrolling by invitation
Electrical stimulation for leg strength in COPD
This trial tests whether a gentle electrical stimulation applied to your leg muscles can help you feel less breathless and less tired during daily activities, and improve your confidence in exercising. It is for people with stable COPD who are already in a pulmonary rehab program.
Kaohsiung, TaiwanAges 18 years+ - NCT06820749Enrolling by invitationPhase 2
Study of HSK31858 tablets for lung mucus conditions
This trial tests an investigational tablet for people with chronic lung diseases like bronchiectasis, COPD, or asthma who produce at least 10 mL of sputum (mucus coughed up from the lungs) each day. The goal is to see if the drug safely reduces excess airway mucus.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05632120Enrolling by invitation
Testing how COPD affects daily movement and participation
This study looks at how chronic obstructive pulmonary disease (COPD) may affect your body function, walking, and ability to take part in everyday life. It may help researchers understand what support or therapies could improve daily activities.
Istanbul, Fatih/İstanbulAges 35–80 - NCT03044847Enrolling by invitation
Long-term study of COPD in adults in China
This study follows people with COPD (chronic lung disease) over many years to better understand the condition. It may help doctors learn what factors predict worsening over time.
Beijing, Beijing MunicipalityAges 40–75 - NCT04911491Recruiting
Breathing muscle training for people with kidney disease
This study tests whether training your breathing muscles can improve health in people with chronic kidney disease (stage 3–4). It may help how your body handles daily activity and circulation-related measurements, compared with usual care.
Aurora, ColoradoAges 50 years+ - NCT06523608Recruiting
Predicting liver problems in advanced chronic liver disease
This study looks at people with advanced chronic liver disease to find ways to predict when they might get worse or develop liver cancer. Researchers hope to use this information to prevent complications and improve care.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06456450Recruiting
Taiwan severe asthma biologic registry study
This study is creating a registry to track the long-term safety and effectiveness of biologic treatments for severe asthma in Taiwan. If you are taking a biologic like omalizumab, mepolizumab, or benralizumab, joining this registry helps doctors learn how well these medicines work over time.
TaichungAges 18 years+ - NCT05846490RecruitingPhase 4
Sleep apnea treatment to improve blood pressure in kidney disease
This study tests whether treating obstructive sleep apnea can help control blood pressure in people with chronic kidney disease. If your sleep apnea is not currently being treated, participation may help your care team see whether safer breathing at night improves blood pressure control.
São PauloAges 18 years+ - NCT06966271Recruiting
Lung medication study for asthma or COPD patients
This study uses computer modeling to see how much of your inhaled medication reaches your lungs. It helps doctors understand how to better treat breathing conditions like asthma or COPD.
BudapestAges 18 years+ - NCT05249634RecruitingPhase 2
Testosterone treatment study for men with chronic kidney disease
This Phase 2 study tests whether testosterone therapy can help men with chronic kidney disease who have low testosterone and related symptoms. It looks to see if treatment is safe and beneficial, while carefully checking heart, blood, prostate, and clotting risks.
St Louis, MissouriAges 18–85 - NCT06985225Recruiting
Study of mucus plugs and lung function in mucus-related lung disease
This study looks at how mucus plugs affect air flow in the lungs. It may help find new ways to treat people with lung conditions like cystic fibrosis, severe asthma, COPD, or bronchiectasis.
Kansas City, KansasAges 18–65 - NCT02777879Recruiting
Study gut-like lung bacteria and inflammation in early COPD
This study looks at the lung’s tiny bacteria (microbiome) and inflammation in people with early COPD who have a smoking history. It compares them with smokers who have normal breathing tests, to better understand what may drive COPD early on.
New York, New YorkAges 18–70 - NCT06090838Recruiting
Balloon angioplasty for blood clots in the lungs after pulmonary embolism
This trial tests whether balloon angioplasty can improve breathing and exercise ability in people who still have symptoms and blood flow problems 3 months or more after a pulmonary embolism. It is for those who have completed a pulmonary rehabilitation program.
Amsterdam, North HollandAges 18–80 - NCT06644144Recruiting
P4O2: A study for people with lung scarring
This study is testing a new way to track lung scarring (fibrosis) over time in people with conditions like IPF, other fibrotic lung diseases, or early signs of scarring. It might help doctors understand how the disease changes.
Amsterdam, North HollandAges 18–80 - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Glendale, CaliforniaAges 18–75 - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT07356076Recruiting
Using electrical impedance tomography to look at lung disease
This study uses a special imaging test called electrical impedance tomography (EIT) to look at how well the lungs work in people with lung diseases like COPD, asthma, pneumonia, or long-term effects from COVID-19. It also includes healthy volunteers to compare results.
OlomoucAges 18 years+ - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Houma, LouisianaAges 18–85 - NCT05798923RecruitingPhase 2
LAM-001 for lung scarring with high blood pressure
This trial tests a new medication called LAM-001 for people with high blood pressure in the lungs caused by lung scarring. It aims to see if it can improve symptoms and help you feel better.
Tucson, ArizonaAges 18–80 - NCT06980584Recruiting
Treating nonthrombotic pulmonary hypertension from fibrosing mediastinitis
This study tests a treatment for a rare lung condition called fibrosing mediastinitis, where scar tissue in the chest presses on the lung artery, causing high blood pressure in the lungs. The goal is to see if the treatment can improve your symptoms and quality of life.
BeijingAges 18–85
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 197 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.