Clinical trials
Chronic Pain Management clinical trials
Below are recruiting chronic pain management clinical trials, each written for real people, not researchers. We’re tracking 219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07267052Recruiting
Nerve stimulation at acupoints for pain relief
This trial uses a gentle electrical device on acupuncture points to study how it affects pain signals in the body. Healthy adults can join to help researchers understand a possible drug-free way to manage pain.
Taichung, Beitun, TaiwanAges 20 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT06899841RecruitingPhase 2/Phase 3
Dexmedetomidine in a nerve block for kidney stone surgery
This study tests whether adding a medicine called dexmedetomidine to a nerve block (an injection near the spine) can improve pain relief after kidney stone surgery. It is for people who are generally healthy and scheduled for a kidney stone procedure.
Asyut, Assiut GovernorateAges 18–70 - NCT07232108Recruiting
Pain medicine options for recovery after laparoscopic hysterectomy
This study compares two types of pain medicine given during laparoscopic hysterectomy: one is a morphine shot into the spine, the other is numbing medicine injected around the surgery cuts and into the belly. The goal is to see which helps you recover better and with less pain.
ErzurumAges 18–65 - NCT06913868Recruiting
Comparing two types of physical therapy for fibromyalgia pain
This study compares a standard physical therapy approach with one based on group consensus to see which works better for fibromyalgia pain. It may help find a more personalized treatment for your condition.
CairoAges 18–65 - NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT07208799RecruitingPhase 2
Steroid comparison for jaw fracture recovery
This trial compares two steroid medicines (dexamethasone and methylprednisolone) to see which one better reduces swelling, pain, and other symptoms after surgery for a broken lower jaw near the chin. It could help you recover faster and with less discomfort.
Multan, Punjab ProvinceAges 18–40 - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT07092566RecruitingPhase 3
Pain relief after robotic kidney surgery: R.E.C.K. vs Exparel
This trial tests two different pain-relief medicines (R.E.C.K. and Exparel) given during robotic kidney surgery. It aims to find which works better to control pain after the operation.
Charlotte, North CarolinaAges 18 years+ - NCT05779852Recruiting
Hypnosis to ease new foot amputation wound pain
This trial tests whether auto-hypnosis (a self-guided calming technique) can reduce pain after a toe or multiple toes are removed. It is for adults who are newly after an amputation and have moderate pain soon after the first dressing.
RennesAges 18 years+ - NCT07070050RecruitingPhase 4
NSAIDs after laparoscopic surgery: continuous or bolus?
This study compares giving NSAID pain relievers continuously through an IV versus as single doses (bolus) after laparoscopic surgery to find which method provides better pain relief with fewer side effects.
Moscow, Moscow OblastAges 18 years+ - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89 - NCT06995534Recruiting
Splint or Exercise for De Quervain's Wrist Pain
This trial compares wearing a splint versus doing specific exercises to treat De Quervain's tenosynovitis, a condition that causes wrist pain and swelling. It may help if you have new or worsening wrist pain without other injuries or diseases.
KonyaAges 18–65 - NCT06977321Recruiting
Taping vs mud therapy for carpal tunnel syndrome
This study tests whether taping therapy (kinesiotaping) or a mud pack treatment (peloidotherapy) can help reduce pain and improve function for people with mild to moderate carpal tunnel syndrome. It may be an option if you want non-surgical, drug-free relief.
KonyaAges 1.5 years–5.4 years - NCT06964282Recruiting
Comparing Two Nerve Blocks for Hip Replacement Pain Relief
This study compares two types of nerve blocks (iliopsoas block and PENG block) to see which one provides better pain relief and recovery after hip replacement surgery. If you are having a hip replacement with spinal anesthesia, you may be a good candidate.
LiègeAges 18 years+ - NCT06931743Recruiting
Electrical stimulation for pain after thyroid surgery
This trial tests if electrical stimulation can help reduce pain after thyroid surgery. It is for people who have at least moderate pain after their operation.
Shanghai, Changning DistrictAges 18 years+ - NCT06745388RecruitingPhase 4
Magnesium for cramping during hysteroscopy or D&C
This study tests whether magnesium can reduce cramping during a hysteroscopy or D&C. If you are having one of these procedures and are not on certain medications, you may qualify.
Royal Oak, MichiganAges 18 years+ - NCT06350409Recruiting
Opioid use after surgery in teens
This study looks at how teens aged 12–17 use opioids after a scheduled surgery. It aims to understand outcomes and help improve pain management.
Aurora, ColoradoAges 12–17 - NCT06283862Recruiting
Virtual cannabis coaching for veterans with chronic pain
This study tests a virtual program to help veterans with chronic pain who are using (or planning to use) CBD or cannabis. You'll join educational sessions and track your symptoms and cannabis use on your smartphone.
Ann Arbor, MichiganAges 18 years+ - NCT06213233RecruitingPhase 2
CBD oil for veterans with chronic pain
This study tests whether CBD oil can help veterans manage chronic pain. You would take a daily dose of CBD and report your symptoms using a smartphone app.
Ann Arbor, MichiganAges 18 years+ - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT05459402RecruitingPhase 2/Phase 3
Methadone dose testing for opioid use disorder pain relief
This study compares taking methadone as one dose versus split into two doses to see which approach works better for people who have pain. It’s meant for adults already on a steady methadone program and who can follow study visits and procedures.
Baltimore, MarylandAges 18–100 - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT07282392Recruiting
Emotional awareness therapy for lupus and fibromyalgia pain
This study tests if a therapy called Emotional Awareness and Expression Therapy (EAET) can help people with lupus and fibromyalgia or chronic widespread pain feel better by addressing emotional factors that may worsen their pain. You would attend sessions to learn how to understand and express your emotions in healthy ways.
Salt Lake City, UtahAges 18–65
Hear when a new Chronic Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic pain management?
- Yes. Clin2 currently lists 219 recruiting chronic pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.