Clinical trials
Chronic Pain Management clinical trials
Below are recruiting chronic pain management clinical trials, each written for real people, not researchers. We’re tracking 219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07558278RecruitingPhase 4
LINQ procedure vs standard care for sacroiliac joint pain
This study compares a new procedure called LINQ—which stabilizes the sacroiliac joint (the joint where your spine connects to your pelvis)—against standard pain management for chronic sacroiliac joint pain. The trial tests whether this procedure reduces pain and disability better than medications and physical therapy alone.
Shenandoah, TexasAges 21 years+ - NCT06603792Recruiting
Brain training for diabetic nerve pain
This study tests whether a brain training method called neurofeedback can help reduce nerve pain caused by diabetes. It may offer a new, non-drug way to manage pain.
OdenseAges 18–82 - NCT07336849Recruiting
Embolization for chronic shoulder pain not helped by other treatments
This trial tests a minimally invasive procedure called transcatheter arterial embolization using tiny particles (Nexsphere-F) to reduce chronic shoulder pain that has not improved with physical therapy, medications, or injections. It aims to see if this treatment can safely improve pain and shoulder movement.
SeoulAges 19–85 - NCT07548567Recruiting
Nerve Block to Reduce Pain During Below-Knee Fracture Surgery
This study tests a nerve-blocking injection (numbing medicine around the femoral artery nerve in your groin area) to help reduce pain and blood pressure changes during below-knee fracture surgery when a tourniquet (pressure cuff) is used. The goal is to see if this approach makes surgery more comfortable and safer.
AthensAges 18 years+ - NCT07303998Recruiting
Brain stimulation and chair yoga for knee pain in Alzheimer's
This study tests two treatments together for people with Alzheimer's who also have chronic knee pain: a gentle brain stimulation (tDCS) and online chair yoga. The goal is to see if these can reduce knee pain and improve daily life.
Tucson, ArizonaAges 60 years+ - NCT07194967Enrolling by invitation
Virtual Reality for Pain Relief During Labor
This trial tests whether using virtual reality can help reduce pain and anxiety during labor. If you are having a low-risk pregnancy and plan a vaginal delivery, you may be able to use a VR headset during contractions to distract from pain.
Ben ArousAges 18–45 - NCT07338045Recruiting
Baduanjin exercise for chronic low back pain in office workers
This trial tests whether an eight-week Baduanjin exercise program can reduce chronic low back pain and improve daily function in office workers. Baduanjin is a gentle mind-body practice that involves slow movements and breathing, and it may help relieve pain caused by prolonged sitting.
Xi'an, ShaanxiAges 20–55 - NCT04734106RecruitingEarly Phase 1
Aloe vera for bladder pain and frequent urination
This early-stage study tests whether aloe vera can reduce symptoms of interstitial cystitis, such as bladder pain and frequent urination. You’d help researchers check both safety and symptom relief.
Winston-Salem, North CarolinaAges 18–80 - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT07860697Recruiting
MRI study of back pain and spine changes
This study looks at MRI images of the lower back to see how body fat, back muscles, and small spine joints relate to long-term back pain. It may help doctors understand back pain better and improve future treatments.
Istanbul, IstanbulAges 18–75 - NCT07812389Recruiting
Opioid-free anesthesia for sinus surgery
This trial tests whether avoiding opioid painkillers during and after sinus surgery helps patients recover faster and with fewer side effects, using a standard recovery plan called ERAS.
Ankara, ÇANKAYAAges 18–65 - NCT06265636Recruiting
Nerve stimulation for jaw pain and function in TMD
This trial tests whether gentle electrical stimulation of a nerve in your jaw can reduce pain and improve chewing, talking, and mouth opening for people with temporomandibular joint disorder (TMD).
Alcorcón, MadridAges 18–65 - NCT04733599Recruiting
Spinal cord stimulation for long-term arm nerve pain
This trial tests whether a high-frequency spinal cord stimulator can reduce long-term nerve pain in the arm after a brachial plexus injury. It may help people whose pain has lasted at least 3 months despite standard treatments.
Jacksonville, FloridaAges 18 years+ - NCT06169488Recruiting
Comparing fusion surgery to rehab for chronic low back pain
This trial compares two approaches for chronic low back pain caused by worn discs: lumbar fusion surgery versus a structured multidisciplinary rehabilitation program. It aims to see which treatment provides better long-term relief and function.
DrammenAges 20–65 - NCT05880212Recruiting
STOPS low back and leg pain approach for Bangladesh
This trial tests a specific physiotherapy program (“STOPS approach”) for people with long-lasting low back pain or leg pain from the back. It aims to see if the structured treatment, delivered by trained physiotherapists, improves pain and function over about 10 weeks.
Dhaka, UttaraAges 18–65 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT06366269Recruiting
Acupuncture first for bladder pain syndrome
This trial tests whether acupuncture can help relieve pain and pressure from bladder pain syndrome (also called interstitial cystitis). Researchers want to see if using acupuncture early can improve symptoms better than usual care.
Cleveland, OhioAges 18–89 - NCT06001541Recruiting
Web program for veterans and caregivers managing health
This study tests a web program to help Veterans and their caregivers work together to manage long-term health conditions like pain, diabetes, or depression. You will join with your live-in caregiver to learn self-management skills online.
Palo Alto, CaliforniaAges 18 years+ - NCT07639944Recruiting
REN Device Study for Jaw Pain and Headaches
This study tests whether a treatment called REN can help reduce headaches and jaw pain caused by temporomandibular disorders (TMD). You would use the REN device at home on your smartphone or tablet over several months.
Newark, DelawareAges 12 years+ - NCT07510269Recruiting
Nerve blocks for pain control during mastectomy
This study tests two different numbing shots for the chest wall to see which one provides better pain relief during and after mastectomy surgery.
Bursa, NilüferAges 18–75 - NCT07504705Recruiting
Comparing two nerve blocks for pain after gallbladder surgery
This trial compares two types of nerve blocks (intertransverse process block and erector spinae plane block) to see which provides better pain relief after gallbladder removal surgery using small incisions (laparoscopic cholecystectomy).
Konya, KonyaAges 18 years+ - NCT07147296Recruiting
Implant to manage blood pressure swings after spinal cord injury
This trial tests an implanted device that may help control drops in blood pressure caused by spinal cord injury. If you often feel dizzy or lightheaded due to low blood pressure, this study could explore whether the device improves stability.
Little Rock, ArkansasAges 18–75 - NCT03099850Recruiting
Studying chronic pancreatitis using follow-up tests
This study follows people with chronic pancreatitis to learn more about the disease and how to better diagnose it. You may have research-related scans or procedures and will be asked to stay in follow-up over time.
Houston, TexasAges 18–75
Hear when a new Chronic Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic pain management?
- Yes. Clin2 currently lists 219 recruiting chronic pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.