Clinical trials · California
Cirrhosis clinical trials in California
We’re tracking 20 recruiting cirrhosis studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
San Francisco, CaliforniaAges 18–75 - NCT06632457RecruitingPhase 3
Survodutide for NASH/MASH cirrhosis: a phase 3 trial
This study tests an investigational drug called survodutide for people with a type of fatty liver disease (NASH or MASH) that has progressed to cirrhosis. The goal is to see if it can improve liver health.
Canoga Park, CaliforniaAges 18 years+ - NCT06419374RecruitingPhase 3
Testing a new drug for liver scarring from MASH
This trial tests a new drug called pegozafermin to see if it can help people with cirrhosis (scarring) of the liver caused by MASH (a fatty liver disease). If you have cirrhosis and either diabetes or multiple risk factors, this study might be an option for you.
Camarillo, CaliforniaAges 18–75 - NCT07029243Recruiting
Prehabilitation and supplement for frail cirrhosis patients
This study tests whether a prehabilitation program (exercise and nutrition planning) along with a supplement containing creatine and whey protein can help improve strength and well-being in people with cirrhosis who are frail. The goal is to see if this combination can help you feel stronger and more active.
San Francisco, CaliforniaAges 18 years+ - NCT04250259RecruitingPhase 2
SAMe treatment study for alcoholic cirrhosis
This Phase 2 study tests whether SAMe can help people with alcoholic cirrhosis (scarred liver) who are in early to mid stages. It may also include healthy volunteers to compare safety and blood/body measurements.
Los Angeles, CaliforniaAges 18–70 - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Los Angeles, CaliforniaAges 18–80 - NCT04873102RecruitingPhase 2
Danazol for low blood counts in some people with cirrhosis
This Phase 2 study tests danazol to improve low blood counts (low white blood cells and/or low platelets) in people with certain types of cirrhosis. It also looks at who may benefit, especially those with specific inherited blood-telomere changes.
Los Angeles, CaliforniaAges 18 years+ - NCT07325526RecruitingPhase 2
Testing a new drug for liver cirrhosis from fatty liver disease
This trial tests if a new medicine, BI 3802876, is safe and tolerable for people with compensated liver cirrhosis caused by MASH (a type of fatty liver disease). Participants must have early-stage cirrhosis without complications like fluid buildup or bleeding.
Coronado, CaliforniaAges 18–75 - NCT06084234RecruitingPhase 4
National liver cancer screening trial
This trial is testing a new way to screen for liver cancer in people with cirrhosis or chronic hepatitis B. It aims to find cancer earlier so it can be treated more effectively.
Los Angeles, CaliforniaAges 18–85 - NCT06051617RecruitingPhase 3
Testing seladelpar for PBC with compensated cirrhosis
This study tests an experimental oral drug called seladelpar for people with PBC who also have cirrhosis that is well-controlled. The goal is to see if it helps improve liver health and manage symptoms without causing serious side effects.
Lancaster, CaliforniaAges 18 years+ - NCT05967273Recruiting
Cirrhosis treatment support system for hospitalized adults
This trial studies a computer-based “CDS” system designed to support care decisions for people hospitalized with cirrhosis. It may help doctors deliver more consistent, safer treatment while you’re in the hospital.
San Francisco, CaliforniaAges 18 years+ - NCT05484206RecruitingPhase 1
Study how liver impairment affects two investigational medicines
This Phase 1 study tests how two investigational medicines move through the body and how safe they are in people with different levels of liver impairment, compared with healthy volunteers. It may help doctors understand dosing and safety for people with liver problems.
Rialto, CaliforniaAges 18–70 - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+ - NCT06528314RecruitingPhase 3
Efruxifermin for NASH-related cirrhosis
This study tests a new medication called efruxifermin for people with cirrhosis (liver scarring) caused by NASH, a type of fatty liver disease. The goal is to see if the drug can help improve liver health and prevent further damage.
Coronado, CaliforniaAges 18–80 - NCT05486572Recruiting
Ultrasound or MRI to help prevent liver cancer deaths
This study compares ultrasound scans versus MRI scans to see which one better helps prevent deaths from liver cancer in people with cirrhosis. You may be assigned to one of the two imaging tests and follow-up visits to track whether liver cancer develops or is caught early.
Sacramento, CaliforniaAges 18–75 - NCT05490888RecruitingPhase 1
Dose study of PHIN-214 for mild to moderate cirrhosis
This Phase 1 study tests how the medicine PHIN-214 behaves in the body and what dose is tolerable in people with Child-Pugh A or B liver cirrhosis. It may help doctors plan safer dosing for future studies.
Coronado, CaliforniaAges 18–75 - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT05199259Recruiting
Blood test study for people at risk for or with liver cancer
This trial tests a new blood test to help detect liver cancer (HCC) or confirm it’s not present in people with cirrhosis who are being monitored. It may help improve how doctors screen for liver cancer and decide who needs further imaging or treatment.
Escondido, CaliforniaAges 18 years+ - NCT06920043RecruitingPhase 2
Study of a new drug for cirrhosis from fatty liver disease
This trial tests a new medication (efimosfermin alfa) for people with cirrhosis (liver scarring) caused by MASH, a type of fatty liver disease. It aims to see if the drug can help improve liver health.
Fresno, CaliforniaAges 18–75 - NCT04539717Enrolling by invitation
Fast MRI test for liver cancer screening
This study tests a quicker MRI screening approach for people with cirrhosis to look for liver cancer early. It may help make liver cancer checkups faster and easier while still finding cancers when they are small.
Los Angeles, CaliforniaAges 18 years+
Cirrhosis trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting cirrhosis studies listed above.
- University of California, San Francisco · 5 studies
- Cedars-Sinai Medical Center · 4 studies
- Southern California Research Center · 3 studies
- 89bio Clinical Study Site · 2 studies
- Akero Clinical Study Site · 2 studies
- Catalina Research Institute · 2 studies
- Inland Empire Clinical Trials · 2 studies
- Kaiser Permanente Los Angeles Medical Center · 2 studies
What taking part in a cirrhosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cirrhosis trials in other states
Common questions
- Are there cirrhosis clinical trials in California?
- Yes. We're currently tracking 20 recruiting cirrhosis studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cirrhosis study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cirrhosis studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.