Clinical trials · Ohio
Cirrhosis clinical trials in Ohio
We’re tracking 17 recruiting cirrhosis studies with a site in Ohio — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
Cleveland, OhioAges 18–75 - NCT03225677Recruiting
Testing a new scan to study muscle breakdown in cirrhosis
This study looks at how your body uses protein in your muscles when you have cirrhosis (a scarred liver). It uses a special “tracer” method (a substance that can be tracked) and may help researchers better understand muscle loss in people with milder cirrhosis.
Cleveland, OhioAges 18 years+ - NCT03121404Recruiting
Study causes of poor nutrition in people with liver scarring
This study looks at why some people with cirrhosis (liver scarring) develop malnutrition, especially when blood flow is redirected during certain surgeries. It may help explain what contributes to low body weight and muscle so better treatments can be planned in the future.
Cleveland, OhioAges 18–70 - NCT06632457RecruitingPhase 3
Survodutide for NASH/MASH cirrhosis: a phase 3 trial
This study tests an investigational drug called survodutide for people with a type of fatty liver disease (NASH or MASH) that has progressed to cirrhosis. The goal is to see if it can improve liver health.
Columbus, OhioAges 18 years+ - NCT06419374RecruitingPhase 3
Testing a new drug for liver scarring from MASH
This trial tests a new drug called pegozafermin to see if it can help people with cirrhosis (scarring) of the liver caused by MASH (a fatty liver disease). If you have cirrhosis and either diabetes or multiple risk factors, this study might be an option for you.
Akron, OhioAges 18–75 - NCT03208868Recruiting
Amino acid drink to help rebuild muscle in cirrhosis
This trial tests whether a special mix of amino acids (building blocks for muscle) can help reverse muscle loss in people with cirrhosis. It aims to improve muscle health while keeping you safe from known complications of liver disease.
Cleveland, OhioAges 18–70 - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Cincinnati, OhioAges 18–80 - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65 - NCT05982769Recruiting
Exercise for cirrhosis patients
This study tests whether a supervised exercise program can help people with cirrhosis (scarred liver) feel stronger and improve their health. You'll be asked to exercise regularly and have tests to see how your muscles and liver respond.
Cleveland, OhioAges 21–65 - NCT06528314RecruitingPhase 3
Efruxifermin for NASH-related cirrhosis
This study tests a new medication called efruxifermin for people with cirrhosis (liver scarring) caused by NASH, a type of fatty liver disease. The goal is to see if the drug can help improve liver health and prevent further damage.
Akron, OhioAges 18–80 - NCT06084234RecruitingPhase 4
National liver cancer screening trial
This trial is testing a new way to screen for liver cancer in people with cirrhosis or chronic hepatitis B. It aims to find cancer earlier so it can be treated more effectively.
Cleveland, OhioAges 18–85 - NCT06051617RecruitingPhase 3
Testing seladelpar for PBC with compensated cirrhosis
This study tests an experimental oral drug called seladelpar for people with PBC who also have cirrhosis that is well-controlled. The goal is to see if it helps improve liver health and manage symptoms without causing serious side effects.
Cleveland, OhioAges 18 years+ - NCT05486572Recruiting
Ultrasound or MRI to help prevent liver cancer deaths
This study compares ultrasound scans versus MRI scans to see which one better helps prevent deaths from liver cancer in people with cirrhosis. You may be assigned to one of the two imaging tests and follow-up visits to track whether liver cancer develops or is caught early.
Cleveland, OhioAges 18–75 - NCT05490888RecruitingPhase 1
Dose study of PHIN-214 for mild to moderate cirrhosis
This Phase 1 study tests how the medicine PHIN-214 behaves in the body and what dose is tolerable in people with Child-Pugh A or B liver cirrhosis. It may help doctors plan safer dosing for future studies.
Cleveland, OhioAges 18–75 - NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT07122700Recruiting
Better tests for fatty liver disease in people with metabolic issues
This study compares new, non-invasive tests to standard liver biopsy for diagnosing fatty liver disease in people with type 2 diabetes or other signs of metabolic syndrome. It aims to see if these simpler tests can replace biopsies.
Columbus, OhioAges 18–75 - NCT07610837RecruitingPhase 2
Testing AZD2389 for fatty liver disease with scarring
This study tests whether a new drug called AZD2389 is safe and well-tolerated in adults with steatotic liver disease (fatty liver) that has progressed to advanced scarring. The trial aims to see if this drug might help slow or improve liver damage in people with this condition.
Westlake, OhioAges 18 years+
Cirrhosis trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting cirrhosis studies listed above.
- Cleveland Clinic · 11 studies
- Clinical Study Site · 2 studies
- The Ohio State University Wexner Medical Center · 2 studies
- 89bio Clinical Study Site
- Akero Clinical Study Site
- Case Western Reserve University
- Clinical Study Site (Various Sponsors)
- DSI Research, LLC
What taking part in a cirrhosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cirrhosis trials in other states
Common questions
- Are there cirrhosis clinical trials in Ohio?
- Yes. We're currently tracking 17 recruiting cirrhosis studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cirrhosis study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cirrhosis studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.