Clinical trials
Clinical clinical trials
Below are recruiting clinical clinical trials, each written for real people, not researchers. We’re tracking 5,427 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04675216Recruiting
Measure pressure in the back part of the brain in serious illness
This study measures pressure inside the skull (intracranial pressure) in adults with serious problems in the back part of the brain. Doctors want to better understand pressure patterns in emergencies like bleeding, tumors, or stroke-related injuries, which may help guide treatment.
Valencia, ValenciaAges 18–80 - NCT04599010Recruiting
Body composition and feeding help for large-for-birth babies
This study looks at how body composition may affect feeding in babies who were “large for gestational age” and have difficulty feeding by mouth. Results may help doctors better identify which babies need extra feeding support and why feeding difficulties happen.
Orlando, FloridaAges 1 week–2 months - NCT04661072Recruiting
Study genes and cancer risk in uterine birth differences
This study looks at how genetic factors and environment may relate to cancer risk in people with uterine birth differences. It also aims to improve clinical care by learning what patterns show up in real-world patients.
New Haven, ConnecticutAges 13 years+ - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04602806Enrolling by invitation
Precision medicine study for traumatic brain injury
This study is looking at people with traumatic brain injuries to improve how they are treated. If you join, you will get an MRI and other tests within the first two days after your injury, and the researchers will track your recovery over time.
San Francisco, CaliforniaAges 18–65 - NCT04598932Enrolling by invitation
Eye pressure and tissue testing for cornea health
This study uses a special, noninvasive microscope technique to study how your cornea tissue behaves. It may help doctors better understand keratoconus and corneal changes after common eye procedures.
Cleveland, OhioAges 18–60 - NCT04660955Enrolling by invitation
10-year follow-up MRI after ACL surgery in young athletes
This study uses an MRI scan to look at knees 10 years after ACL reconstruction. It helps researchers understand how the knee changes over time after sports-related ACL injury, and how well reconstruction lasts.
Cleveland, OhioAges 22–45 - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT04511013RecruitingPhase 2
Trial for BRAF-mutant melanoma spread to the brain
This Phase 2 study tests whether a 3-drug plan (encorafenib + binimetinib + nivolumab) works better than ipilimumab + nivolumab for melanoma that has spread to the brain. If you qualify, you’ll get either treatment and have frequent brain scans to track how well it controls the tumors.
Birmingham, AlabamaAges 18 years+ - NCT04521699Recruiting
CalmiGo stress device to improve heart blood vessel health
This study looks at whether a stress-management device (CalmiGo) can improve blood vessel function and heart disease risk in people recovering from recent heart procedures. You would use the device for 12 weeks and complete questionnaires, blood tests, and a heart-vessel test at the start and end.
Rochester, MinnesotaAges 18 years+ - NCT04517838Recruiting
Testing immune responses to anti-HER2 breast cancer treatments
This study looks at how your immune system reacts to anti-HER2 treatments in people with HER2-positive breast cancer. It may help doctors understand who responds best by studying immune signals in blood (and sometimes tissue) during or after treatment.
Jacksonville, FloridaAges 18 years+ - NCT04575688Enrolling by invitationPhase 4
Nerve-block injection options for ankle or heel surgery
This trial compares two methods of numbing pain—an injection near the joint versus a nerve block—during ankle or hindfoot surgery. It aims to see which approach helps with comfort and recovery after surgery.
Germantown, TennesseeAges 18–80 - NCT04565366Enrolling by invitation
Study of research care for new spinal cord injuries
This study looks at people after a recent, serious injury—especially a new spinal cord injury—to see how research and clinical knowledge can be improved. Depending on your group (spinal cord injury, other trauma, or healthy), you may be invited to participate if you meet age and injury timing needs.
Fresno, CaliforniaAges 18 years+ - NCT04543253Recruiting
Recovery study after Cushing surgery for cortisol excess
This study looks at how people recover after surgery to treat Cushing syndrome and mild cortisol overproduction. It may help doctors understand what recovery looks like and how treatment affects cortisol levels and symptoms.
Rochester, MinnesotaAges 18 years+ - NCT04521764RecruitingPhase 1
Vaccine for Metastatic Breast Cancer
This trial tests a vaccine (MV-s-NAP) that is injected directly into a tumor to stimulate your immune system against breast cancer. It is for people with metastatic breast cancer that has spread despite prior treatments.
Rochester, MinnesotaAges 18 years+ - NCT04588285RecruitingPhase 2
Ambroxol for new and early dementia with Lewy bodies
This trial tests whether ambroxol (a mouth medicine) can help people with new or early dementia with Lewy bodies (DLB) or mild cognitive impairment linked to DLB. Participants take the medicine for about 18 months while the study tracks safety and changes over time.
Haugesund, HaugesundAges 50–85 - NCT04582279Recruiting
Lung ultrasound test to rule out rejection after lung transplant
This study checks whether a painless lung ultrasound can help tell when rejection is unlikely after a lung transplant. If it works, it could reduce the need for other tests in people who feel well.
Jacksonville, FloridaAges 18 years+ - NCT04509050Recruiting
Testing a highly effective CF medicine in young children
This study looks at how well a highly effective cystic fibrosis (CF) medicine works in infants and young children, and what biological changes it causes. It may help families understand whether the medicine improves CF function and related measures early in life.
Birmingham, AlabamaAges Up to 10 years - NCT04503213Enrolling by invitation
Testing CSF1R brain disease after stem cell transplant
This study looks at how CSF1R-related leukoencephalopathy (a genetic brain condition) behaves after a stem cell transplant. It may help doctors understand expected brain and walking changes after treatment.
Jacksonville, FloridaAges 18 years+ - NCT04569162Recruiting
RCDP patient registry for children with related genetic conditions
This trial is a registry that collects medical and genetic information from people with rhizomelic chondrodysplasia punctata (RCDP) or closely related conditions. It helps researchers better understand the condition and plan future studies that could lead to better care.
Wilmington, DelawareAges Any age - NCT04576793RecruitingPhase 2
Imaging brain inflammation in Alzheimer’s and related variants over time
This Phase 2 study uses repeated brain MRI scans to track “microglial activation,” which is a marker of brain immune/inflammation activity, in different Alzheimer’s-related conditions. It may help researchers understand how brain inflammation changes over time and differs between people with these clinical variants.
New York, New YorkAges 50 years+ - NCT04521881RecruitingPhase 3
Testing an antifibrinolytic for mild head injury in older adults
This study tests whether an anti-bleeding medicine (given to reduce unwanted clot breakdown) can improve outcomes after a mild head injury in people 50 and older. It is looking for patients who arrive quickly after injury and have certain symptoms like brief loss of consciousness, confusion, or nausea.
London, LondonAges 50 years+ - NCT04567771Recruiting
Proton vs IMRT radiation after surgery for uterine or cervical cancer
This study compares two types of radiation therapy (proton and IMRT) given after surgery for endometrial or cervical cancer. It aims to see which treatment is better at reducing side effects while still being effective.
Scottsdale, ArizonaAges 18 years+ - NCT04513808RecruitingPhase 3
Compare IV versus inhaled anesthesia for esophageal surgery
This trial tests whether using IV anesthesia (given through a vein) or inhaled anesthesia helps people live longer without their esophageal cancer coming back after surgery. You’d be randomly assigned to one anesthesia type as part of potentially curative surgery.
ShanghaiAges 18–90
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Common questions
- Are there clinical trials for clinical?
- Yes. Clin2 currently lists 5,427 recruiting clinical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a clinical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a clinical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.