Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT05127616Recruiting
Trial for chronic pelvic pain: CBT vs education/support
This study tests whether structured talking therapy (CBT) or education/support helps reduce chronic pelvic pain problems in adults. It compares two approaches over time and uses symptom diaries and follow-up check-ins to see which works better.
Los Angeles, CaliforniaAges 18–70 - NCT05129150Recruiting
Assessing brain function with an ultrasound in a day hospital
This trial studies brain function in people who are already going to a day hospital for memory and thinking assessments. It may help researchers better understand cognitive problems and improve how they are evaluated. You would likely be asked to complete an ultrasound exam of the brain and allow your information to be used for the study.
ToursAges Any age - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80 - NCT04997642Recruiting
Parkinson’s patient database for memory and movement tracking
This study builds a research database of people who receive care for Parkinson’s disease, including those with mild memory problems or dementia. It aims to collect consistent information that researchers can use to better understand Parkinson’s and related thinking changes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04938349Recruiting
Dual-task training for memory and balance in older adults
This trial tests a type of training that challenges you to do two tasks at once to help with thinking and movement. It is for people over 55 who may have mild memory problems but do not have major brain, heart, or lung conditions.
Chicago, IllinoisAges 55 years+ - NCT04960566Enrolling by invitation
Behavior therapy for reflux symptoms tied to stress responses
This study tests a behavioral approach for people with GERD whose reflux symptoms keep coming back even after they tried an acid-blocking medicine (a PPI). It aims to help by targeting stress-related body responses that may worsen symptoms.
Chicago, IllinoisAges 18–80 - NCT03810794Recruiting
Acupuncture study for people with Alzheimer’s memory problems
This trial tests whether acupuncture can improve symptoms in people with Alzheimer’s disease. You may qualify if you have memory and thinking changes consistent with Alzheimer’s and meet imaging and brain-scan score requirements.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT04864080Recruiting
Online study to measure brain-related signals in pain or depression
This trial uses an online study platform to look for “cognitive biomarkers,” which are measurable patterns in thinking or brain-related responses. It compares people with pain or depression to healthy controls to see how these patterns differ and could help future research or care.
Minneapolis, MinnesotaAges 18 years+ - NCT04883255RecruitingEarly Phase 1
Study cannabis effects on brain function in adults with HIV
This early-phase study looks at how cannabis (and the body’s cannabinoid system) may affect thinking and brain-related measures in people with HIV. You may be asked to avoid cannabis and complete several brain and health assessments to see how these factors relate.
San Diego, CaliforniaAges 18–65 - NCT04906863Recruiting
Genetic study for early dementia in adults and families
This trial studies genes to better understand why some people develop dementia and memory problems earlier in life. It may help researchers find clearer causes and improve future testing and treatments for families affected by dementia.
New York, New YorkAges 35 years+ - NCT04898790Recruiting
Testing ways to improve thinking after bone marrow transplant
This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.
Omaha, NebraskaAges 19 years+ - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT04810858Recruiting
Study how chronic marijuana affects brain inflammation in HIV
This study looks at whether ongoing marijuana use changes “brain inflammation” and brain cell injury in people living with HIV. It may help researchers understand potential risks or protective effects and how treatment and brain health interact.
Winston-Salem, North CarolinaAges 25–59 - NCT04824248Recruiting
Weight-loss program for chronic low back pain
This trial studies whether weight loss can improve long-lasting, non-specific low back pain. It may help people whose back pain is partly related to extra weight by testing a structured approach over time.
BrusselsAges 18–65 - NCT04816006Recruiting
Breast cancer, thinking, and exercise study
This trial tests whether exercise can help thinking and reasoning in women over 50 who have had early-stage breast cancer. It compares a moderate exercise program with health education sessions.
Phoenix, ArizonaAges 50 years+ - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT04731519Recruiting
Group treatment to help Veterans after a recent suicidal crisis
This trial studies a “recovery-oriented” group therapy for Veterans who had a suicide attempt or started planning within the last year. It aims to help reduce risk and improve coping and recovery after a post-acute suicidal episode.
The Bronx, New YorkAges 18 years+ - NCT04757220Recruiting
Study of apathy in people with schizophrenia or depression
This study looks at “apathy,” or reduced motivation/interest, in people with schizophrenia or depression. It may help researchers understand what drives apathy and how to measure it in a clearer, more complete way.
StrasbourgAges 18–60 - NCT04751435Recruiting
Genetic testing education for cancer patients of diverse backgrounds
This study tests new educational materials about genetic testing for cancer patients. It aims to find the best ways to explain genetic testing to people from different backgrounds, especially Black, Latino, and non-Latino non-Black communities.
Brooklyn, New YorkAges 18 years+ - NCT04715984Recruiting
Testing brain-circuit targets during DBS surgery in Parkinson’s
This study looks at how brain connections involved in movement may relate to thinking and memory problems in Parkinson’s disease. It happens during a deep brain stimulation (DBS) operation, using tests while the surgeon is placing an electrode.
Nashville, TennesseeAges 40 years+ - NCT04653012Recruiting
Testing brain-activity recordings in people with drug-resistant epilepsy
This study looks at brain activity using electrodes placed inside the brain in people with focal, drug-resistant epilepsy before surgery. It may help doctors better map where seizures start and improve planning for treatment.
ParisAges 18 years+ - NCT04639336Recruiting
Pompe disease study of brain and nerve effects
This study looks at how Pompe disease affects the brain and nervous system. You may be able to join if you have a confirmed diagnosis of infantile or late-onset Pompe disease and agree to participate.
Durham, North CarolinaAges birth–18 years
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.