Clinical trials
Cognitive Functioning clinical trials
Below are recruiting cognitive functioning clinical trials, each written for real people, not researchers. We’re tracking 334 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07485816Enrolling by invitation
Heart-brain oxygen and thinking changes in heart failure
This study looks at how well your heart and brain work together to use oxygen, and how that relates to changes in thinking and memory for people with heart failure.
Kunming, YunnanAges 18–70 - NCT07164768Enrolling by invitation
Thinking and mood in kids with type 1 diabetes
This study looks at how type 1 diabetes affects thinking skills and emotional health in children, teens, and young adults. Both the young person and one of their parents will answer questions together.
Pune, MaharashtraAges 10–21 - NCT06888700Enrolling by invitation
tDCS to improve social thinking in heroin recovery
This study uses a gentle brain stimulation technique called tDCS (transcranial direct current stimulation) to improve social thinking skills in people recovering from heroin addiction. It's for adults in early recovery who are in a rehabilitation center.
Xi'an, ShaanxiAges 30–60 - NCT04042532Enrolling by invitation
Theta-burst brain stimulation for younger-onset Alzheimer’s
This trial tests whether a form of brain stimulation (theta-burst stimulation) can improve thinking and memory in people with younger-onset Alzheimer’s. It also compares results with people without dementia who meet similar age and health requirements.
Taoyuan, GuishanAges 50–75 - NCT04343157RecruitingPhase 2
Image-guided focused radiation to protect thinking in brain metastases
This Phase 2 trial tests a brain radiation technique that aims to treat up to a few brain metastases while sparing areas important for thinking and memory. It may help people keep cognitive abilities better than with more brain-wide radiation approaches.
San Diego, CaliforniaAges 18 years+ - NCT04201600Recruiting
Study how blood sugar swings affect thinking in prediabetes
This study looks at how “blood sugar variability” (how much glucose levels bounce around) may affect thinking and memory in people with prediabetes. You may be eligible if you’re older and don’t already have diabetes or conditions that can strongly affect the brain or blood vessels.
Baltimore, MarylandAges 50 years+ - NCT06604000Recruiting
Goal management training for cognitive control after brain injury
This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.
TrondheimAges 18–65 - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
New York, New YorkAges 55 years+ - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT05339438Recruiting
Brain scan mapping before epilepsy surgery
This study uses a special MRI scan to map parts of the front-temporal brain in people with drug-resistant epilepsy who may need surgery. The goal is to better plan surgery by showing which brain areas are involved.
NancyAges 18 years+ - NCT05062369Recruiting
Brain stimulation plus training to support alcohol abstinence
This study tests whether a combination of brain stimulation (tDCS) and cognitive training can help people with alcohol use disorder stay abstinent. You may be included if you are currently not drinking and can commit to the program timeline.
Minneapolis, MinnesotaAges 18–65 - NCT06937554Recruiting
Function and nutrition in fit leukemia patients
This trial looks at how exercise and nutrition affect fit adult leukemia patients during intensive chemotherapy. It aims to understand how to best support your recovery and well-being.
Rome, RMAges 18–70 - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT05895344Recruiting
Compare proton vs modern radiation effects on thinking
This study compares two types of radiation—proton therapy versus modern fractionated radiation—to see how they affect long-term thinking (cognitive function) and daily abilities in people with a specific skull-base tumor. It may help clarify which radiation approach best protects brain and nerve function over time.
CaenAges 18–70 - NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT06634147Recruiting
Exercise program to prevent decline in hospitalized older adults
This study is testing a gentle exercise program for older adults (75+) while they are in the hospital. The goal is to see if it helps prevent loss of strength, memory, or thinking skills.
Pamplona, NavarreAges 75 years+ - NCT04616300Recruiting
Exercise program to support brain function during breast cancer chemo
This trial studies whether a structured exercise program can help protect or improve thinking and memory in people with breast cancer while they are starting chemotherapy after surgery. It may help with “chemo brain” by targeting brain function during treatment.
Toronto, OntarioAges 18–65 - NCT04759326Recruiting
Hippotherapy after stroke to improve movement and function
This trial studies whether therapy using a horse (hippotherapy) can help adults who still have stroke-related physical difficulties more than 3 months after their stroke. It aims to improve daily function and movement when standard recovery has not been enough.
La CanourgueAges 18 years+ - NCT05619068Recruiting
Study tracking outcomes in Moyamoya disease
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
Beijing, Beijing MunicipalityAges 10–60 - NCT06236919Recruiting
Virtual reality for emotional regulation in kids and teens
This study tests a virtual reality program designed to help children and teens learn to manage their emotions. It's offered in schools and aims to improve emotional regulation skills.
BarcelonaAges 10–16 - NCT06850350Recruiting
Long COVID and Thinking & Walking
This study looks at how Long COVID affects thinking and movement skills. If you had COVID-19 more than 3 months ago and could walk before you got sick, you may be able to help researchers understand these lasting symptoms.
Chicago, IllinoisAges 18 years+ - NCT07181122Recruiting
Quality of life and thinking ability in men with advanced prostate cancer
This study looks at how treatment affects your daily life, mood, sleep, and thinking skills. It is for men starting hormone therapy combined with another drug for prostate cancer that has spread.
Ankara, YenimahalleAges 18 years+ - NCT07536503Recruiting
How Sleep Quality Affects Thinking and Function in MS
This study looks at whether better sleep helps people with multiple sclerosis (MS) think more clearly and stay more physically active. Researchers will measure your sleep quality and test your memory and everyday abilities to see if they're connected.
Ankara, AnkaraAges 18–65 - NCT07145294RecruitingPhase 1/Phase 2
Stem cell therapy to improve thinking after stroke
This trial tests whether tiny particles from stem cells can help people recover thinking and memory after a recent stroke. Doctors will check if the treatment is safe and if it boosts brain function.
ShanghaiAges 18 years+
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Common questions
- Are there clinical trials for cognitive functioning?
- Yes. Clin2 currently lists 334 recruiting cognitive functioning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive functioning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive functioning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.