Clinical trials
Cognitive Functioning clinical trials
Below are recruiting cognitive functioning clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07267845Recruiting
Effect of alpha-GPC on thinking and exercise performance
This study tests whether a supplement called alpha-GPC (a nutrient that supports brain health) can improve memory, thinking, and physical performance in healthy adults. You would take the supplement and complete cognitive tests and exercise tasks over several visits.
Cork, County CorkAges 25–55 - NCT07268768Recruiting
Personality, thinking, and sensitivity in headache
This study looks at how personality, thinking skills, and heightened nerve sensitivity are connected in people with headache. It aims to better understand these relationships to improve care.
Messina, SicilyAges 18–60 - NCT07267559RecruitingPhase 4
Daridorexant and emotion brain testing study
This study tests a medication called daridorexant, which affects the brain's sleep-wake system, to see how it influences emotions and thinking. You will take one dose and complete computer tasks that measure how you process emotional information.
OxfordAges 18–40 - NCT06897553Recruiting
ACT for Better Mental Health with Neurologic Illness
This study tests a type of talk therapy (ACT) to help people with neurological conditions like Parkinson’s, MS, or epilepsy feel better emotionally. It's for those who are struggling with depression, anxiety, or stress and are ready to work on their mental health.
BielefeldAges 18 years+ - NCT07233941Recruiting
Cognitive and psychological study in migraine patients
This study looks at thinking abilities and psychological factors in people with migraines. It aims to understand how migraine affects memory, attention, and emotions.
MilanAges 18–65 - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT06250842Recruiting
Benzodiazepine impact on brain function study
This study uses brain scans to understand how long-term benzodiazepine use affects thinking and memory. It compares people who have taken benzodiazepines for at least 3 months with those who have not.
Dalian, LiaoningAges 18–80 - NCT07208916Recruiting
Can eating grapes boost strength and thinking in older women?
This study tests whether eating grapes daily can help improve muscle strength and memory in healthy women aged 65 and older. If you join, you will need to follow a special diet that limits certain foods and supplements.
Springfield, MassachusettsAges 65 years+ - NCT07164768Enrolling by invitation
Thinking and mood in kids with type 1 diabetes
This study looks at how type 1 diabetes affects thinking skills and emotional health in children, teens, and young adults. Both the young person and one of their parents will answer questions together.
Pune, MaharashtraAges 10–21 - NCT07154199Recruiting
Ultrasound for brain fog after COVID-19
This trial tests if gentle ultrasound waves to the head can help clear brain fog that lasts after a COVID-19 infection. If you've had COVID and still feel mentally slow or forgetful, this treatment might help your thinking get sharper.
Beijing, Beijing MunicipalityAges 18–75 - NCT07084701Recruiting
Lymphatic drainage for memory in sleep-deprived college students
This study tests if a gentle, non-invasive neck and head massage technique, called lymphatic drainage, can help improve memory and thinking in college students who are not sleeping enough. It is a preliminary study to see if the idea works.
TianjinAges 18 years+ - NCT07071181Recruiting
Milk-based drinks for better sleep and health
This trial tests whether drinking a milk-based drink every day for four weeks can improve gut health, sleep quality, and heart health. It may be a good option if you have trouble sleeping and are overweight.
Leeds, West YorkshireAges 40–70 - NCT07051655Recruiting
Ketone drink for thinking and memory
This study tests whether a drink containing ketones (a natural energy source for the brain) can improve thinking and memory. It involves three groups: people with obesity, lean people, and athletes.
Birmingham, AlabamaAges 19–55 - NCT07034794Recruiting
Lysoveta for memory in healthy adults with mild memory concerns
This study tests whether a supplement called Lysoveta can help with memory and thinking in healthy adults who have mild memory problems. You would take the supplement or a placebo daily for several weeks and visit a clinic for memory tests and questionnaires.
London, OntarioAges 50–75 - NCT06677359Recruiting
Creatine and exercise for older adults
This study tests whether a creatine supplement, taken with or without a gentle exercise program, can help older adults stay stronger and more independent. It's designed for people aged 75 and older who can still walk.
Pamplona, NavarreAges 75 years+ - NCT04490733Recruiting
Test dual-task walking to improve thinking in colorectal cancer
This study looks at a walking exercise that makes you do two tasks at once (for example, walking while focusing on something) to see if it can improve thinking and memory. It is for people newly diagnosed with early to mid-stage colorectal cancer, and excludes people with other cancers or cancer coming back.
TaipeiAges 40–75 - NCT06888700Enrolling by invitation
tDCS to improve social thinking in heroin recovery
This study uses a gentle brain stimulation technique called tDCS (transcranial direct current stimulation) to improve social thinking skills in people recovering from heroin addiction. It's for adults in early recovery who are in a rehabilitation center.
Xi'an, ShaanxiAges 30–60 - NCT06747689Recruiting
Sleep quality and self-care in heart failure
This study looks at how sleep quality affects the ability of people with heart failure to manage their own health. It aims to find if better sleep leads to better self-care.
IzmirAges 18 years+ - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06700187Recruiting
Does reducing sitting time improve thinking?
This study looks at whether taking short breaks from sitting can help your brain work better. You will visit a lab 4 times and will be asked to sit or take short breaks while your thinking is tested.
MaastrichtAges 18–35 - NCT05982730Recruiting
Segway training for balance and thinking in Parkinson's
This study tests whether practicing balance on a Segway can improve walking and thinking for people with moderate Parkinson's. You will train on a Segway while getting special sensory cues, and researchers will see if it helps your motor skills and cognitive function.
Dallas, TexasAges 50–85 - NCT06615973Recruiting
Stroke recovery and social factors study
This study looks at how social factors (like where you live or your income) might affect thinking and memory after a stroke. If you had a stroke before and joined a related study, you may be able to join this one.
Bethesda, MarylandAges 18–99 - NCT04694534Recruiting
Serious game program to help thinking skills in multiple sclerosis
This trial tests whether a computer “serious game” can improve thinking and memory skills in people with multiple sclerosis (MS). It’s designed for adults who report thinking problems and show weaker-than-average results on specific brain tests.
Arras, Hauts-de-FranceAges 18–65
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Common questions
- Are there clinical trials for cognitive functioning?
- Yes. Clin2 currently lists 315 recruiting cognitive functioning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive functioning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive functioning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.